全文获取类型
收费全文 | 546篇 |
免费 | 12篇 |
国内免费 | 1篇 |
专业分类
化学 | 329篇 |
晶体学 | 4篇 |
力学 | 16篇 |
数学 | 76篇 |
物理学 | 134篇 |
出版年
2023年 | 8篇 |
2022年 | 14篇 |
2021年 | 11篇 |
2020年 | 11篇 |
2019年 | 17篇 |
2018年 | 8篇 |
2017年 | 6篇 |
2016年 | 20篇 |
2015年 | 20篇 |
2014年 | 27篇 |
2013年 | 41篇 |
2012年 | 31篇 |
2011年 | 43篇 |
2010年 | 25篇 |
2009年 | 23篇 |
2008年 | 19篇 |
2007年 | 24篇 |
2006年 | 23篇 |
2005年 | 31篇 |
2004年 | 25篇 |
2003年 | 19篇 |
2002年 | 13篇 |
2001年 | 15篇 |
2000年 | 10篇 |
1999年 | 9篇 |
1998年 | 7篇 |
1997年 | 3篇 |
1996年 | 3篇 |
1995年 | 3篇 |
1994年 | 9篇 |
1993年 | 4篇 |
1992年 | 8篇 |
1991年 | 3篇 |
1990年 | 2篇 |
1989年 | 2篇 |
1988年 | 2篇 |
1987年 | 2篇 |
1986年 | 3篇 |
1985年 | 4篇 |
1984年 | 2篇 |
1983年 | 1篇 |
1980年 | 1篇 |
1979年 | 2篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1973年 | 1篇 |
1972年 | 1篇 |
排序方式: 共有559条查询结果,搜索用时 15 毫秒
81.
The objectives of this study were to produce sodium alginate (SA)-based cryogel beads filled with different concentrations (0, 0.4, 1.0, and 2.5%, w/w) of hydroxypropyl distarch phosphate (HDP) as a curcumin delivery system and to investigate the physicochemical, structural, and in vitro gastrointestinal tract release properties of the cryogel beads. According to FT-IR analysis, the formation of ionic crosslinking between SA and Ca2+ and the presence of HDP were found. XRD analysis demonstrated the successful encapsulation of curcumin in the beads by observing the disappearance of the characteristic peaks of curcumin. SEM analysis results revelated that SA-based cryogel beads exhibited a denser internal structure as the HDP concentration was increased. The encapsulation efficiency of curcumin in SA cryogel beads filled with HDP concentration from 0% to 2.5% was increased from 31.95% to 76.66%, respectively, indicating that HDP can be a suitable filler for the encapsulation of curcumin in the production of SA-based cryogel beads. After exposure to simulated gastric fluid (SGF) and simulated intestinal fluid (SIF), the release rate of curcumin was decreased as HDP concentration was increased. Accordingly, SA-based cryogel beads filled with HDP can be utilized for the delivery system of curcumin in the food industry. 相似文献
82.
Jagadeesh Nagarajappa Masagalli Melanayakanakatte Kuberappa BasavanaGowda Hee-Sung Chae Won Jun Choi 《Molecules (Basel, Switzerland)》2021,26(5)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key factor in several cardiovascular diseases, as it is responsible for the elevation of circulating low-density lipoprotein cholesterol (LDL-C) levels in blood plasma by direct interaction with the LDL receptor. The development of orally available drugs to inhibit this PCSK9-LDLR interaction is a highly desirable objective. Here, we report the synthesis of naturally occurring moracin compounds and their derivatives with a 2-arylbenzofuran motif to inhibit PCSK9 expression. In addition, we discuss a short approach involving the three-step synthesis of moracin C and a divergent method to obtain various analogs from one starting material. Among the tested derivatives, compound 7 (97.1%) was identified as a more potent inhibitor of PCSK9 expression in HepG2 cells than berberine (60.9%). These results provide a better understanding of the structure–activity relationships of moracin derivatives for the inhibition of PCSK9 expression in human hepatocytes. 相似文献
83.
Dongho Chae 《Journal of Differential Equations》2006,227(2):640-651
We obtain new continuation principle of the local classical solutions of the 3D Euler equations, where the regularity condition of the direction field of the vorticiy and the integrability condition of the magnitude of the vorticity are incorporated simultaneously. The regularity of the vorticity direction field is most appropriately measured by the Triebel-Lizorkin type of norm. Similar result is also obtained for the inviscid 2D quasi-geostrophic equation. 相似文献
84.
Jae-Ou Chae Vladimir Demidiouk Jae-Won Hwang Tae Gyun Jung V. Ravi 《Reaction Kinetics and Catalysis Letters》2005,85(1):167-173
Summary A number of supported metal oxide catalysts were prepared and tested for nitrogen oxide removal from diesel engine exhaust. More than 50% of nitrogen oxides were removed using many prepared catalysts in the temperature range of 150oC-350oC. 相似文献
85.
The atomic structure of Cs atoms adsorbed on the Si(0 0 1)(2 × 1) surface has been investigated by coaxial impact collision ion scattering spectroscopy. When 0.5 ML of Cs atoms are adsorbed on Si(0 0 1) at room temperature, it is found that Cs atoms occupy a single absorption site on T3 with a height of 3.18 ± 0.05 Å from the second layer of Si(0 0 1)(2 × 1) surface, and the bond length between Cs and the nearest Si atoms is 3.71 ± 0.05 Å. 相似文献
86.
Li F Buchnev O Cheon CI Glushchenko A Reshetnyak V Reznikov Y Sluckin TJ West JL 《Physical review letters》2006,97(14):147801
We investigated the physical properties of low concentration ferroelectric nematic colloids, using calorimetry, optical methods, infrared spectroscopy, and capacitance studies. The resulting homogeneous colloids possess a significantly amplified nematic orientational coupling. We find that the nematic orientation coupling increases by approximately 10% for particle concentrations of 0.2%. A manifestation of the increased orientational order is that the clearing temperature of a nematic colloid increases by up to 40 degrees C compared to the pure liquid crystal host. A theoretical model is proposed in which the ferroelectric particles induce local dipoles whose effective interaction is proportional to the square of the orientational order parameter. 相似文献
87.
Seung Wook Shin In Young Kim K.V. Gurav Chae Hwan Jeong Jae Ho Yun P.S. Patil Jeong Yong Lee Jin Hyeok Kim 《Current Applied Physics》2013,13(8):1837-1843
Cu2ZnSn(SxS1?x)4 (CZTSSe) thin films were prepared by annealing a stacked precursor prepared on Mo coated glass substrates by the sputtering technique. The stacked precursor thin films were prepared from Cu, SnS2, and ZnS targets at room temperature with stacking orders of Cu/SnS2/ZnS. The stacked precursor thin films were annealed using a tubular two zone furnace system under a mixed N2 (95%) + H2S (5%) + Se vaporization atmosphere at 580 °C for 2 h. The effects of different Se vaporization temperature from 250 °C to 500 °C on the structural, morphological, chemical, and optical properties of the CZTSSe thin films were investigated. X-ray diffraction patterns, Raman spectroscopy, and X-ray photoelectron spectroscopy results showed that the annealed thin films had a single kesterite crystal structure without a secondary phase. The 2θ angle position for the peaks from the (112) plane in the annealed thin films decreased with increasing Se vaporization temperature. Energy dispersive X-ray results showed that the presence of Se in annealed thin films increased from 0 at% to 42.7 at% with increasing Se vaporization temperatures. UV–VIS spectroscopy results showed that the absorption coefficient of all the annealed thin films was over 104 cm?1 and that the optical band gap energy decreased from 1.5 eV to 1.05 eV with increasing Se vaporization temperature. 相似文献
88.
89.
We present the compatibility of elastomeric stamp, poly(dimethylsiloxane) (PDMS), with inks for non-photolithography. This ink limitation is important in considering the lamination of hydrophilic solution on the patterned ink surface using an elastomeric stamp. We focus on an increase of the hydrophobicity of the patterned surface due to diffusion of low molecular weight (LMW) silicone polymer chains. This hydrophobicity increases inversely with the PDMS–ink interaction parameter (χ), which is correlated with the solubility parameter (δ). This study's results translate into proposed design factors for ink used in the patterned functional layer for PDMS-based lithography. Both the XPS and the contact angle measurement show that the hydrophobicity can be increased by LMW PDMS chains transfer from stamps, and this increase can cause the expansion of the free volume in PDMS pores through a swelling effect. 相似文献
90.
Ohgew Kweon Seong-Jae Kim Songjoon Baek Jong-Chan Chae Michael D Adjei Dong-Heon Baek Young-Chang Kim Carl E Cerniglia 《BMC biochemistry》2008,9(1):11