全文获取类型
收费全文 | 1290篇 |
免费 | 36篇 |
国内免费 | 2篇 |
专业分类
化学 | 798篇 |
晶体学 | 8篇 |
力学 | 37篇 |
数学 | 173篇 |
物理学 | 312篇 |
出版年
2024年 | 3篇 |
2023年 | 10篇 |
2022年 | 37篇 |
2021年 | 36篇 |
2020年 | 32篇 |
2019年 | 31篇 |
2018年 | 30篇 |
2017年 | 22篇 |
2016年 | 59篇 |
2015年 | 32篇 |
2014年 | 56篇 |
2013年 | 90篇 |
2012年 | 78篇 |
2011年 | 94篇 |
2010年 | 70篇 |
2009年 | 97篇 |
2008年 | 82篇 |
2007年 | 76篇 |
2006年 | 51篇 |
2005年 | 35篇 |
2004年 | 35篇 |
2003年 | 27篇 |
2002年 | 19篇 |
2001年 | 30篇 |
2000年 | 28篇 |
1999年 | 17篇 |
1998年 | 14篇 |
1997年 | 12篇 |
1996年 | 26篇 |
1995年 | 15篇 |
1994年 | 11篇 |
1993年 | 7篇 |
1992年 | 10篇 |
1991年 | 11篇 |
1990年 | 3篇 |
1989年 | 7篇 |
1988年 | 3篇 |
1986年 | 4篇 |
1985年 | 4篇 |
1984年 | 4篇 |
1983年 | 4篇 |
1982年 | 4篇 |
1977年 | 2篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1973年 | 1篇 |
1956年 | 1篇 |
1955年 | 1篇 |
1937年 | 1篇 |
1933年 | 1篇 |
排序方式: 共有1328条查询结果,搜索用时 15 毫秒
91.
R. M. Parr A. Fajgelj R. Dekner H. Vera Ruiz F. P. Carvalho P. P. Povinec 《Analytical and bioanalytical chemistry》1998,360(3-4):287-290
For many years the International Atomic Energy Agency (IAEA) has been promoting analytical quality assurance and quality control in its Member States with emphasis on measurands that are amenable to analysis by nuclear and related techniques, i.e. radionuclides, trace elements, and stable isotopes. This paper reviews briefly the rationale for some of these activities, particularly in relation to the needs of participants in developing countries arising out of co-ordinated research programmes, technical co-operation projects and global and regional networks. Emphasis is given to biological and environmental reference materials with a matrix of natural origin. Also described are some activities arising out of the requirements of ISO-25 and other relevant international quality standards. 相似文献
92.
Rangel TB Assreuy AM Pires Ade F Carvalho AU Benevides RG Simões Rda C Silva HC Bezerra MJ Nascimento AS Nascimento KS Nagano CS Sampaio AH Delatorre P Rocha BA Fernandes PM Cavada BS 《Molecules (Basel, Switzerland)》2011,16(6):5087-5103
DwL, a lectin extracted from the seeds of Dioclea wilsonii, is a metalloprotein with strong agglutinating activity against rabbit and ABO erythrocytes, inhibited by glucose and mannose. DwL was purified by affinity chromatography on a Sephadex G-50 column and ion exchange chromatography on a HiTrap SP XL column. SDS-PAGE revealed three electrophoretic bands corresponding to the α (25,634 ± 2 Da), β (12,873 ± 2 Da) and γ (12,779 ± 2 Da) chains. Protein sequencing was done by Tandem Mass Spectrometry. The primary sequence featured 237 amino acids and was highly homologous to other reported Diocleinae lectins. A complete X-ray dataset was collected at 2.0 ? for X-Man-complexed DWL crystals produced by the vapor diffusion method. The crystals were orthorhombic and belonged to the space group I222, with the unit-cell parameters a = 59.6, b = 67.9 and c = 109.0 ?. DWL differed in potency from other ConA-like lectins and was found to induce neutrophil migration in rats, making it particularly useful in structural/functional studies of this class of proteins. 相似文献
93.
Mónica S. EstevãoLuísa C. Carvalho Luísa M. FerreiraEduarda Fernandes M. Manuel B. Marques 《Tetrahedron letters》2011,52(1):101-106
The electrochemical behavior of an indole library of compounds, including several tryptophan and tryptamine derivatives previously demonstrated to be active against several reactive oxygen species (ROS), was investigated. For this purpose, a voltammetry study was undertaken and the oxidation potential was correlated to the scavenging activity reported for the studied indoles. All the compounds showed an oxidation potential peak lower than that observed for indole (Epox = 1.035 V), but higher than that described for the antioxidant melatonin (Epox = 0.715 V). The electrochemical behavior showed a high correlation with the scavenging activity of peroxyl radical, for selected compounds. 相似文献
94.
Evaluation of grinding methods for pellets preparation aiming at the analysis of plant materials by laser induced breakdown spectrometry 总被引:1,自引:0,他引:1
It has been demonstrated that laser induced breakdown spectrometry (LIBS) can be used as an alternative method for the determination of macro (P, K, Ca, Mg) and micronutrients (B, Fe, Cu, Mn, Zn) in pellets of plant materials. However, information is required regarding the sample preparation for plant analysis by LIBS. In this work, methods involving cryogenic grinding and planetary ball milling were evaluated for leaves comminution before pellets preparation. The particle sizes were associated to chemical sample properties such as fiber and cellulose contents, as well as to pellets porosity and density. The pellets were ablated at 30 different sites by applying 25 laser pulses per site (Nd:YAG@1064 nm, 5 ns, 10 Hz, 25 J cm−2). The plasma emission collected by lenses was directed through an optical fiber towards a high resolution echelle spectrometer equipped with an ICCD. Delay time and integration time gate were fixed at 2.0 and 4.5 μs, respectively. Experiments carried out with pellets of sugarcane, orange tree and soy leaves showed a significant effect of the plant species for choosing the most appropriate grinding conditions. By using ball milling with agate materials, 20 min grinding for orange tree and soy, and 60 min for sugarcane leaves led to particle size distributions generally lower than 75 μm. Cryogenic grinding yielded similar particle size distributions after 10 min for orange tree, 20 min for soy and 30 min for sugarcane leaves. There was up to 50% emission signal enhancement on LIBS measurements for most elements by improving particle size distribution and consequently the pellet porosity. 相似文献
95.
Carvalho AP Gomes JA Cordeiro MN 《Journal of chemical information and computer sciences》2000,40(3):588-592
Molecular simulation methods such as molecular dynamics and Monte Carlo are fundamental for the theoretical calculation of macroscopic and microscopic properties of chemical and biochemical systems. These methods often rely on heavy computations, and one sometimes feels the need to run them in powerful massively parallel machines. For moderate problem sizes, however, a not so powerful and less expensive solution based on a network of workstations may be quite satisfactory. In the present work, the strategy adopted in the development of a parallel version is outlined, using the message passing model, of a molecular simulation code to be used in a network of workstations. This parallel code is the adaptation of an older sequential code using the Metropolis Monte Carlo method. In this case, the message passing interface was used as the interprocess communications library, although the code could be easily adapted for other message passing systems such as the parallel virtual machine. For simple systems it is shown that speedups of 2 can be achieved for four processes with this cheap solution. For bigger and more complex simulated systems, even better speedups might be obtained, which indicates that the presented approach is appropriate for the efficient use of a network of workstations in parallel processing. 相似文献
96.
Hellyda K. T. A. Silva Thiago Chellappa Fabíola C. Carvalho Edjane F. B. Silva Tarcísio A. Nascimento Antônio S. Araújo Valter J. FernandesJr. 《Journal of Thermal Analysis and Calorimetry》2011,106(3):731-733
Biodiesel is defined as a mixture of mono- or di-alquil esters of vegetable oil or animal fats. During long-term storage,
oxidation caused by contact with air (autoxidation) presents a legitimate concern in relation to monitoring and maintaining
fuel quality. Extensive oxidative degradation may compromise the quality by adversely affecting kinematic viscosity, acid
value, or peroxide value. The oxidation susceptibility of biodiesel, due to the presence of triacilglycerides of poly-unsaturated
fatty acids, was evaluated in this study. Samples of sunflower, castor, and soybean biodiesels were obtained through the transesterification
reaction, with the intention of achieving the thermal stability study through thermogravimetrical analyses and differential
scanning calorimetry high pressure. It was furthermore observed through thermogravimetry and pressure differential scanning
calorimetry curves that castor biodiesel exhibited the highest thermal and oxidative stability. 相似文献
97.
The disrupting effect of three different ionic carbohydrates (xanthan, pectin and gum arabic) on the formation of tannin-protein insoluble aggregates was assessed by nephelometry using bovine serum albumin (BSA) and several procyanidin fractions previously extracted from grape seeds. The presence in solution of any of the carbohydrates studied was found to restrain the formation of insoluble protein-tannin aggregates for every procyanidin fraction used. Xanthan was the most effective carbohydrate, whereas gum arabic was the least effective. The present work has revealed that the disrupting effect of carbohydrates is quite different depending on the procyanidin structure complexity. In general, the three carbohydrates studied revealed a similar trend in that their disrupting effect on tannin-BSA aggregate formation decreased with increase of the procyanidin degree of polymerization. 相似文献
98.
Carlos E. M. Carvalho Solange M. S. V. Wardell James L. Wardell Janet M. S. Skakle John N. Low Christopher Glidewell 《Acta Crystallographica. Section C, Structural Chemistry》2004,60(1):o28-o32
Molecules of the title compounds N2‐(benzoyloxy)benzamidine, C14H12N2O2, (I), N2‐(2‐hydroxybenzoyloxy)benzamidine, C14H12N2O3, (II), and N2‐benzoyloxy‐2‐hydroxybenzamidine, C14H12N2O3, (III), all have extended chain conformations, with the aryl groups remote from one another. In (I), the molecules are linked into chains by a single N—H⋯N hydrogen bond [H⋯N = 2.15 Å, N⋯N = 3.029 (2) Å and N—H⋯N = 153°] and these chains are linked into sheets by means of aromatic π–π stacking interactions. There is one intramolecular O—H⋯O hydrogen bond in (II), and a combination of one three‐centre N—H⋯(N,O) hydrogen bond [H⋯N = 2.46 Å, H⋯O = 2.31 Å, N⋯N = 3.190 (2) Å, N⋯O = 3.146 (2) Å, N—H⋯N = 138° and N—H⋯O = 154°] and one two‐centre C—H⋯O hydrogen bond [H⋯O = 2.46 Å, C⋯O = 3.405 (2) Å and C—H⋯O = 173°] links the molecules into sheets. In (III), an intramolecular O—H⋯N hydrogen bond and two N—H⋯O hydrogen bonds [H⋯O = 2.26 and 2.10 Å, N⋯O = 2.975 (2) and 2.954 (2) Å, and N—H⋯O = 138 and 163°] link the molecules into sheets. 相似文献
99.
100.
Maurício Hilgemann Fritz Scholz Heike Kahlert Leandro Machado de Carvalho Marcelo Barcellos da Rosa Ulrike Lindequist Martina Wurster Paulo C. do Nascimento Denise Bohrer 《Electroanalysis》2010,22(4):406-412
A new electrochemical assay has been developed which is based on quantifying the attack of OH. radicals on a self‐assembled thiol monolayer on electrodes in the presence and absence of antioxidants. The OH. radicals were produced in Fenton solutions. The radical scavengers diminish the concentration of the OH. radicals in the Fenton solution, and the extent of thiol layer destruction is monitored with the help of a redox probe in solution, the signal of which is only generated at SAM‐free electrode surface. The results of the electrochemical assay were compared with those of the standard DPPH. assay. In case of each plant extract, an excellent linear correlation was observed between the radical scavenging activity and the concentration of plant extracts; however, the scavenging properties of different plants strongly differ in the electrochemical and the DPPH. assay. Since the proposed new method probes the reactivity of radical scavengers towards OH., one of the most important reactive oxygen radicals in tissues, it is supposed to provide much more relevant information than the DPPH. or other assays. 相似文献