全文获取类型
收费全文 | 521篇 |
免费 | 24篇 |
专业分类
化学 | 333篇 |
晶体学 | 2篇 |
力学 | 9篇 |
数学 | 60篇 |
物理学 | 141篇 |
出版年
2023年 | 2篇 |
2022年 | 24篇 |
2021年 | 18篇 |
2020年 | 16篇 |
2019年 | 21篇 |
2018年 | 15篇 |
2017年 | 11篇 |
2016年 | 28篇 |
2015年 | 18篇 |
2014年 | 23篇 |
2013年 | 34篇 |
2012年 | 45篇 |
2011年 | 37篇 |
2010年 | 28篇 |
2009年 | 27篇 |
2008年 | 36篇 |
2007年 | 17篇 |
2006年 | 28篇 |
2005年 | 12篇 |
2004年 | 18篇 |
2003年 | 7篇 |
2002年 | 9篇 |
2001年 | 6篇 |
2000年 | 6篇 |
1999年 | 8篇 |
1998年 | 6篇 |
1997年 | 10篇 |
1996年 | 4篇 |
1995年 | 2篇 |
1994年 | 7篇 |
1992年 | 1篇 |
1991年 | 7篇 |
1990年 | 2篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1987年 | 3篇 |
1984年 | 1篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1977年 | 1篇 |
1975年 | 2篇 |
1973年 | 1篇 |
排序方式: 共有545条查询结果,搜索用时 15 毫秒
101.
Ademar B. Lugao Lucia Noda Elisabeth. C. L. Cardoso Beatriz Hustzler Shinichi Tokumoto Ana Nery F. Mendes 《Radiation Physics and Chemistry》2002,63(3-6):509-512
It is well known that polypropylene undergoes simultaneous crosslinking and degradation under irradiation. However, there are speculations regarding the formation of branching under special conditions. It is also well known that the melt-strength property of a polymer increases with molecular weight and with long-chain branching due to the increase in the entanglement level. This study was a contribution to the understanding of the following points: the role of molecular weight, the role of structural modifications on nucleation properties; the structural changes on polypropylene.
The results showed that degradation was the major reaction in the initial step of irradiation, however, the largely modified molecules concentrated in the high molecular weight fraction. The results also confirm that the branching formation is likely to occur. 相似文献
102.
During an exothermic reaction in a fluid, convection may ensue on a local scale and then develop to the scale of the entire vessel. In this work, we study the effects of both localised and global convection on thermal explosions occurring between parallel plates. Analytical relations are derived for the various transitions in regimes of convective and thermal behaviours. We show that these relations agree well with previous numerical work and with new simulations in the present investigation. We also determine analytically the time for onset of convection, as well as the temperature increase at that time, for stable and explosive systems. The effects of the Prandtl number of the fluid on the transitions between regimes are noted. 相似文献
103.
Martins PT Velazquez-Campoy A Vaz WL Cardoso RM Valério J Moreno MJ 《Journal of the American Chemical Society》2012,134(9):4184-4195
Passive transport across cell membranes is the major route for the permeation of xenobiotics through tight endothelia such as the blood–brain barrier. The rate of passive permeation through lipid bilayers for a given drug is therefore a critical step in the prediction of its pharmacodynamics. We describe a detailed study on the kinetics and thermodynamics for the interaction of chlorpromazine (CPZ), an antipsychotic drug used in the treatment of schizophrenia, with neutral and negatively charged lipid bilayers. Isothermal titration calorimetry was used to study the partition and translocation of CPZ in lipid membranes composed of pure POPC, POPC:POPS (9:1), and POPC:Chol:POPS (6:3:1). The membrane charge due to the presence of POPS as well as the additional charge resulting from the introduction of CPZ in the membrane were taken into account, allowing the calculation of the intrinsic partition coefficients (K(P)) and the enthalpy change (ΔH) associated with the process. The enthalpy change upon partition to all lipid bilayers studied is negative, but a significant entropy contribution was also observed for partition to the neutral membrane. Because of the positive charge of CPZ, the presence of negatively charged lipids in the bilayer increases both the observed amount of CPZ that partitions to the membrane (KP(obs)) and the magnitude of ΔH. However, when the electrostatic effects are discounted, the intrinsic partition coefficient was smaller, indicating that the hydrophobic contribution was less significant for the negatively charged membrane. The presence of cholesterol strongly decreases the affinity of CPZ for the bilayer in terms of both the amount of CPZ that associates with the membrane and the interaction enthalpy. A quantitative characterization of the rate of CPZ translocation through membranes composed of pure POPC and POPC:POPS (9:1) was also performed using an innovative methodology developed in this work based on the kinetics of the heat evolved due to the interaction of CPZ with the membranes. 相似文献
104.
César IC Byrro RM de Santana E Silva Cardoso FF Mundim IM de Souza Teixeira L Rezende KR da Silva EP Gomes SA de Sousa VA Bonfim RR Pianetti GA 《Biomedical chromatography : BMC》2012,26(7):851-856
A rapid method for the quantification of glucosamine in human plasma using high‐performance liquid chromatography coupled to tandem mass spectrometry was developed and validated. The sample preparation includes a simple deproteinization step, using d ‐[1‐13C] glucosamine hydrochloride as an internal standard. Chromatographic separation was performed on an ACE Ciano column using isocratic elution with acetonitrile and aqueous 2 mm ammonium acetate containing 0.025% formic acid (80:20). Selected reaction monitoring was performed using the transitions m/z 180.1 → m/z 72.1 and m/z 181.0 → m/z 74.6 to quantify glucosamine and internal standard, respectively. The method was validated and proved to be linear, accurate and precise over the range 50–5000 ng/mL of glucosamine. Recovery rates higher than 90% were obtained for both glucosamine and internal standard. No matrix effect was detected in the samples. The validated method was successfully applied to a pharmacokinetic study after oral administration of a powder for oral solution formulation containing glucosamine sulfate. Copyright © 2011 John Wiley & Sons, Ltd. 相似文献
105.
In the present paper we study Anderson localization of Bose-Einstein condensate with a weakly positive nonlinearity under the influence of chaotic potentials. We investigate the one-dimensional Gross-Pitaevskii equation numerically, in order to unveil the influence of the parameters that describe the potential and nonlinearity on the localization of the condensate. The results show that matter localization is possible, in certain regions in parameter space. Similarities to chaotically disordered photonic lattices suggest that the results are of direct interest to such photonic lattices as well. 相似文献
106.
Josepha Yohanna de Jesus Eliane Santos de Carvalho Dantas Mairim Russo Serafini Paula dos Passos Menezes Juliana Cordeiro Cardoso Ricardo Luiz Cavalcanti Albuquerque-Jr Jivaldo do Rosário Matos Juliana Ferreira de Oliveira Irwin Rose Alencar de Menezes Francilene Amaral da Silva Adriano Antunes de Souza Araújo 《Journal of Thermal Analysis and Calorimetry》2016,123(3):2003-2012
107.
108.
Vanessa F. Cardoso Ana R. Machado Vânia C. Pinto Paulo J. Sousa Gabriela Botelho Graça Minas Senentxu Lanceros‐Méndez 《Journal of Polymer Science.Polymer Physics》2016,54(18):1802-1810
The manufacture of three‐dimensional patterned electroactive poly(vinylidene fluoride‐co‐chlorotrifluoroethylene) microstructures with tailored architecture, morphology, and wettability is presented. The patterned microstructures are fabricated using a simple, effective, low cost, and reproducible technique based on microfluidic technology. These novel structures can represent innovative platforms for advanced strategies in a wide range of biotechnological applications, including tissue engineering, drug delivery, microfluidic, and sensors and actuators devices. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2016 , 54, 1802–1810 相似文献
109.