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61.
62.
A series of 2,1,3‐ and 1,2,4‐benzothiadiazine derivatives were synthesized by alkylation via Mitsunobu reaction and evaluated for their antiviral activity against ADV, HHV‐6, Cox‐B5 and H‐CMV. Most of them were active at micromolar level against one or more viral strains. All the molecules studied are poorly cytotoxic (maximum non toxic concentrations were >25μM), except one compound that presents a higher cytotoxicity (maximum non toxic concentration was 6 μM). 相似文献
63.
Bruni Giovanna Monteforte Francesco Maggi Lauretta Friuli Valeria Ferrara Chiara Mustarelli Piercarlo Girella Alessandro Berbenni Vittorio Capsoni Doretta Milanese Chiara Marini Amedeo 《Journal of Thermal Analysis and Calorimetry》2020,140(4):1859-1869
Journal of Thermal Analysis and Calorimetry - The eco-friendly method of kneading was here used to synthesize a cocrystal of probenecid, an uricosuric drug used in treating gout and hyperuricemia,... 相似文献
64.
Remarks on Singularities, Dimension and Energy Dissipation for Ideal Hydrodynamics and MHD 总被引:1,自引:0,他引:1
Russel E. Caflisch Isaac Klapper Gregory Steele 《Communications in Mathematical Physics》1997,184(2):443-455
For weak solutions of the incompressible Euler equations, there is energy conservation if the velocity is in the Besov space
B
3
s
with s greater than 1/3. B
3
s
consists of functions that are Lip(s) (i.e., H?lder continuous with exponent s) measured in the L
p
norm. Here this result is applied to a velocity field that is Lip(α0) except on a set of co-dimension on which it is Lip($agr;1), with uniformity that will be made precise below. We show that the Frisch-Parisi multifractal formalism is valid (at least
in one direction) for such a function, and that there is energy conservation if . Analogous conservation results are derived for the equations of incompressible ideal MHD (i.e., zero viscosity and resistivity)
for both energy and helicity . In addition, a necessary condition is derived for singularity development in ideal MHD generalizing
the Beale-Kato-Majda condition for ideal hydrodynamics.
Received: 21 March 1995 / Accepted: 6 August 1996 相似文献
65.
66.
Salceanu Daniela-Crina Pincu Elena Bruni Giovanna Marini Amedeo Meltzer Viorica 《Journal of Thermal Analysis and Calorimetry》2018,132(2):1095-1103
Journal of Thermal Analysis and Calorimetry - The physico-chemical characterization of norfloxacin commercial sample (NF), norfloxacin anhydrous form A (NFanhA), norfloxacin pentahydrate... 相似文献
67.
Bruni Giovanna Sakaj Mirena Berbenni Vittorio Maggi Lauretta Friuli Valeria Girella Alessandro Milanese Chiara Marini Amedeo 《Journal of Thermal Analysis and Calorimetry》2019,136(5):2063-2070
Journal of Thermal Analysis and Calorimetry - Sulindac is a nonsteroidal anti-inflammatory drug with poor water solubility. This study presents a way to increase its dissolution rate while reducing... 相似文献
68.
Maria Carmela Lombardo Russel E. Caflisch Marco Sammartino 《Journal of statistical physics》2008,130(1):69-82
In this paper we study the interaction of a fluid with a wall in the framework of the kinetic theory. We consider the possibility
that the fluid molecules can penetrate the wall to be reflected by the inner layers of the wall. This results in a scattering
kernel which is a non-local generalization of the classical Maxwell scattering kernel. The proposed scattering kernel satisfies
a global mass conservation law and a generalized reciprocity relation. We study the hydrodynamic limit performing a Knudsen
layer analysis, and derive a new class of (weakly) nonlocal boundary conditions to be imposed to the Navier–Stokes equations. 相似文献
69.
It has been proposed recently to observe the change in cosmological redshift of distant galaxies or quasars with the next generation of large telescope and ultra-stable spectrographs (the so-called Sandage–Loeb test). Here we investigate the possibility of observing the change in peculiar velocity in nearby clusters and galaxies. This “peculiar acceleration” could help reconstructing the gravitational potential without assuming virialization. We show that the expected effect is of the same order of magnitude of the cosmological velocity shift. Finally, we discuss how to convert the theoretical predictions into quantities directly related to observations. 相似文献
70.
Amedeo Premoli 《Mathematical Programming》1986,36(2):210-227
A compact algorithm is presented for solving the convex piecewise-linear-programming problem, formulated by means of a separable
convex piecewise-linear objective function (to be minimized) and a set of linear constraints. This algorithm consists of a
finite sequence of cycles, derived from the simplex method, characteritic of linear programming, and the line search, characteristic
of nonlinear programming. Both the required storage and amount of calculation are reduced with respect to the usual approach,
based on a linear-programming formulation with an expanded tableau. The tableau dimensions arem×(n+1), wherem is the number of constraints andn the number of the (original) structural variables, and they do not increase with the number of breakpoints of the piecewise-linear
terms constituting the objective function. 相似文献