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61.
Membrane preparations from growing regions of pea stems and actively-dividing mouse L-cells form lipid-linked saccharides from GDP-mannose and UDP-N-acetylglucosamine. These lipids have properties which are consistent with those of mono- and di-phosphoryl polyisoprenyl derivatives. In experiments using plant membranes, the monophosphoryl derivative labeled with GDP-(14C) mannose contains mannose only, while the diphosphoryl derivative labeled with the same nucleotide sugar is heterogeneous, containing oligosaccharides corresponding to mannosaccharides of 5, 7, and 9--12 residues. Only the diphosphoryl polyisoprenyl derivatives are labeled with UDP-(14C)glucosamine and these contain predominantly chitobiose and N-acetylglucosamine itself. Unlabeled GDP-mannose added after UDP-N-acetyl-(14C)glucosamine results in the formation of higher lipid-linked oligosaccharides which are apparently the same as those which are labeled with GDP-(14C)mannose alone. Incubation of the membranes with GDP-(14C)mannose in the presence of Mn2+, unlabeled UDP-glucose or unlabeled UDP-N-acetylglucosamine results in marked changes in the accumulation of both the polyisoprenyl monophosphoryl mannose and polyisoprenyl diphosphoryl oligosaccharides. Animal cell membranes synthesise lipid-linked oligosaccharides when incubated with UDP-N-acetylglucosamine and GDP-mannose. These oligosaccharides are similar in size to those synthesised by the plant membranes but their formation is more efficient. The potential roles of these compounds in glycoprotein biosynthesis in both plant and animal tissues is discussed. 相似文献
62.
Acosta D Affolder T Albrow MG Ambrose D Amidei D Anikeev K Antos J Apollinari G Arisawa T Artikov A Ashmanskas W Azfar F Azzi-Bacchetta P Bacchetta N Bachacou H Badgett W Barbaro-Galtieri A Barnes VE Barnett BA Baroiant S Barone M Bauer G Bedeschi F Behari S Belforte S Bell WH Bellettini G Bellinger J Benjamin D Beretvas A Bhatti A Binkley M Bisello D Bishai M Blair RE Blocker C Bloom K Blumenfeld B Bocci A Bodek A Bolla G Bolshov A Bortoletto D Boudreau J Bromberg C Brubaker E Budagov J 《Physical review letters》2005,94(17):171802
We report the first largely model independent measurement of charged particle multiplicities in quark and gluon jets, Nq and Ng, produced at the Fermilab Tevatron in pp collisions with a center-of-mass energy of 1.8 TeV and recorded by the Collider Detector at Fermilab. The measurements are made for jets with average energies of 41 and 53 GeV by counting charged particle tracks in cones with opening angles of theta(c) = 0.28, 0.36, and 0.47 rad around the jet axis. The corresponding jet hardness Q = Ejet theta c varies in the range from 12 to 25 GeV. At Q = 19.2 GeV, the ratio of multiplicities r = Ng/Nq is found to be 1.64+/-0.17, where statistical and systematic uncertainties are added in quadrature. The results are in agreement with resummed perturbative QCD calculations. 相似文献
63.
[structure: see text] A convergent, stereoselective total synthesis of the macrolide antitumor agent rhizoxin D is described. (+)-DIPCl-promoted asymmetric aldol reaction, Evans-Tishchenko 1,3-diol synthesis, modified Julia coupling, and Horner-Wadsworth-Emmons reactions are featured. 相似文献
64.
For a given excited state there exist densities that arise from more than one external potential. This is due to a qualitatively different energy-density relationship from that of the ground state and is related to positive eigenvalues in the nonlocal susceptibility for excited states. Resulting problems with the generalization of the density functional methodology to excited states are discussed. 相似文献
65.
Abe K Abe K Abe T Adam I Akimoto H Aston D Baird KG Baltay C Band HR Barklow TL Bauer JM Bellodi G Berger R Blaylock G Bogart JR Bower GR Brau JE Breidenbach M Bugg WM Burke D Burnett TH Burrows PN Calcaterra A Cassell R Chou A Cohn HO Coller JA Convery MR Cook V Cowan RF Crawford G Damerell CJ Daoudi M de Groot N de Sangro R Dong DN Doser M Dubois R Erofeeva I Eschenburg V Fahey S Falciai D Fernandez JP Flood K Frey R Hart EL Hasuko K Hertzbach SS Huffer ME Huynh X Iwasaki M Jackson DJ 《Physical review letters》2003,90(14):141804
We present an improved direct measurement of the parity-violation parameter A(b) in the Z boson-b-quark coupling using a self-calibrating track-charge technique applied to a sample enriched in Z-->bb events via the topological reconstruction of the B hadron mass. Manipulation of the Stanford Linear Collider electron-beam polarization permits the measurement of A(b) to be made independently of other Z-pole coupling parameters. From the 1996-1998 sample of 400,000 hadronic Z decays, produced with an average beam polarization of 73.4%, we find A(b)=0.906+/-0.022(stat)+/-0.023(syst). 相似文献
66.
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68.
On Borel Sets in Function Spaces with the Weak Topology 总被引:1,自引:0,他引:1
It is proved that the duality map ,:(, weak)x(()*, weak*)R isnot Borel. More generally, the evaluation e:(C)(K),x KR, e(f,x) = f(x), is not Borel for any function space C(K) on a compactF-space. It is also shown that a non-coincidence of norm-Boreland weak-Borel sets in a function space does not imply thatthe duality map is non-Borel. 相似文献
69.
We show that with the weak topology is not an intersection of Borel sets in its Cech-Stone extension (and hence in any compactification). Assuming (CH), this implies that has no continuous injection onto a Borel set in a compact space, or onto a Lindelöf space. Under (CH), this answers a question of Arhangel'ski.
70.
Although they are simple techniques from the early days of timetabling research, graph colouring heuristics are still attracting
significant research interest in the timetabling research community. These heuristics involve simple ordering strategies to
first select and colour those vertices that are most likely to cause trouble if deferred until later. Most of this work used
a single heuristic to measure the difficulty of a vertex. Relatively less attention has been paid to select an appropriate
colour for the selected vertex. Some recent work has demonstrated the superiority of combining a number of different heuristics
for vertex and colour selection. In this paper, we explore this direction and introduce a new strategy of using linear combinations
of heuristics for weighted graphs which model the timetabling problems under consideration. The weights of the heuristic combinations
define specific roles that each simple heuristic contributes to the process of ordering vertices. We include specific explanations
for the design of our strategy and present the experimental results on a set of benchmark real world examination timetabling
problem instances. New best results for several instances have been obtained using this method when compared with other constructive
methods applied to this benchmark dataset. 相似文献