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811.
Irene Ara Fatima El Bahij Mohamed Lachkar Najib Ben Larbi 《Acta Crystallographica. Section C, Structural Chemistry》2003,59(5):m199-m200
The Pd atom in the title compound, [Pd(C3H5OS2)2], lies on an inversion center and adopts a square‐planar coordination geometry defined by the four S atoms of the two dithiocarbonate (xanthate) ligands. In the solid state, the molecules aggregate into layers in which the rows of molecules alternate their orientation to allow each Pd atom to interact with two symmetry‐equivalent S atoms of the xanthate ligands of adjacent molecules, generating a pseudo‐octahedral environment around each Pd atom. This weak interaction of 3.3579 (7) Å can be classified as a closed‐shell electrostatic intermolecular interaction. 相似文献
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815.
816.
María Rodríguez-García Guillermo Fernndez-Varo Susana Hidalgo Gabriela Rodríguez Irene Martínez Muling Zeng Eudald Casals Manuel Morales-Ruiz Gregori Casals 《Molecules (Basel, Switzerland)》2022,27(6)
Circulating levels of 2-hydroxybutyrate (2HB) are highly related to glycemic status in different metabolomic studies. According to recent evidence, 2HB is an early biomarker of the future development of dysglycemia and type 2 diabetes mellitus and may be causally related to the progression of normal subjects to impaired fasting glucose or insulin resistance. In the present study, we developed and validated a simple, specific and sensitive gas chromatography-mass spectrometry (GC-MS) method specifically intended to quantify serum levels of 2HB. Liquid–liquid extraction with ethyl acetate was followed by 2 min of microwave-assisted derivatization. The method presented acceptable accuracy, precision and recovery, and the limit of quantification was 5 µM. Levels of 2HB were found to be stable in serum after three freeze-thaw cycles, and at ambient temperature and at a temperature of 4 °C for up to 24 h. Extracts derivatized under microwave irradiation were stable for up to 96 h. No differences were found in 2HB concentrations measured in serum or plasma EDTA samples. In summary, the method is useful for a rapid, precise and accurate quantification of 2HB in serum samples assessed for the evaluation of dysglycemia and diabetes mellitus. 相似文献
817.
Hugo L. Bianchi Irene Dujovne Roberto Fernández-Prini 《Journal of solution chemistry》2000,29(3):237-253
Conductivity equations, based on the mean spherical approximation (MSA), haverecently been derived. We compare their performance with that of classicalequations at the level of experimental uncertainty using conductivity data forsome typical electrolyte solutions. For symmetrical electrolytes, the pictureisconsistent showing a better performance for the classical equations. The Leeand Wheaton equation also shows advantages at moderate concentrations. Forunsymmetrical electrolytes, the differences between MSA and classical equationsis larger. There is, however, an inherent inconsistency with the equilibriuminformation, which cannot be resolved at present. 相似文献
818.
Symmetric branching random walk on a homogeneous tree exhibits a weak survival phase: For parameter values in a certain interval, the population survives forever with positive probability, but, with probability
one, eventually vacates every finite subset of the tree. In this phase, particle trails must converge to the geometric boundaryΩ of the tree. The random subset Λ of the boundary consisting of all ends of the tree in which the population survives, called
the limit set of the process, is shown to have Hausdorff dimension no larger than one half the Hausdorff dimension of the entire geometric
boundary. Moreover, there is strict inequality at the phase separation point between weak and strong survival except when the branching random walk is isotropic. It is further shown that in all cases there is a distinguished probability measure μ supported by Ω such that the Hausdorff
dimension of Λ∩Ωμ, where Ωμ is the set of μ-generic points of Ω, converges to one half the Hausdorff dimension of Ωμ at the phase separation point. Exact formulas are obtained for the Hausdorff dimensions of Λ and Λ∩Ωμ, and it is shown that the log Hausdorff dimension of Λ has critical exponent 1/2 at the phase separation point.
Received: 30 June 1998 / Revised version: 10 March 1999 相似文献
819.
Hongxia Wang Meiyan Cui Gaoliang Fu Jiaye Zhang Xingyu Ding Irene Azaceta Matthew Bugnet Demie M.Kepaptsoglou Vlado K.Lazarov Victor A.de la Pe?a O'Shea Freddy E.Oropeza Kelvin H.L.Zhang 《中国科学:化学(英文版)》2022,65(10):1885-1894
The design of heterostructured transition metal-based electrocatalysts with controlled composition and interfaces is key to increasing the efficiency of the water electrolysis and the elucidation of reaction mechanisms.In this work,we report the synthesis of well-controlled vertically aligned Ni/NiO nanocomposites consisting of Ni nanoclusters embedded in NiO,which result in highly efficient electrocatalysts for overall water splitting.We show that such a high catalytic efficiency toward both th... 相似文献
820.
Graham J. Moore Harry Ridgway Konstantinos Kelaidonis Christos T. Chasapis Irene Ligielli Thomas Mavromoustakos Joanna Bojarska John M. Matsoukas 《Molecules (Basel, Switzerland)》2022,27(15)
Angiotensin receptor blockers (ARBs) used in the treatment of hypertension and potentially in SARS-CoV-2 infection exhibit inverse agonist effects at angiotensin AR1 receptors, suggesting the receptor may have evolved to accommodate naturally occurring angiotensin ‘antipeptides’. Screening of the human genome has identified a peptide (EGVYVHPV) encoded by mRNA, complementary to that encoding ANG II itself, which is an inverse agonist. Thus, opposite strands of DNA encode peptides with opposite effects at AR1 receptors. Agonism and inverse agonism at AR1 receptors can be explained by a receptor ‘switching’ between an activated state invoking receptor dimerization/G protein coupling and an inverse agonist state mediated by an alternative/second messenger that is slow to reverse. Both receptor states appear to be driven by the formation of the ANG II charge-relay system involving TyrOH-His/imidazole-Carboxylate (analogous to serine proteases). In this system, tyrosinate species formed are essential for activating AT1 and AT2 receptors. ANGII is also known to bind to the zinc-coordinated metalloprotease angiotensin converting enzyme 2 (ACE2) used by the COVID-19 virus to enter cells. Here we report in silico results demonstrating the binding of a new class of anionic biphenyl-tetrazole sartans (‘Bisartans’) to the active site zinc atom of the endopeptidase Neprilysin (NEP) involved in regulating hypertension, by modulating humoral levels of beneficial vasoactive peptides in the RAS such as vasodilator angiotensin (1–7). In vivo and modeling evidence further suggest Bisartans can inhibit ANG II-induced pulmonary edema and may be useful in combatting SARS-CoV-2 infection by inhibiting ACE2-mediated viral entry to cells. 相似文献