Reaction of alkyl splitting of 4-acetylamino-N-(3,5-di-tert-butyl-4-hydroxybenzyl)-benzenesulfonamide

Russian Journal of General Chemistry - Alkyl splitting of 4-acetylamino-N-(3,5-di-tert-butyl-4-hydroxybenzyl)benzenesulfonamide with alkali solution has been discovered, the reaction being uncommon...     

The Proximity and Josephson Effects in Niobium Nitride–Aluminum Bilayers

Physics of the Solid State - Highly disordered thin films of niobium nitride and the specific features of the proximity effect in NbN (S)–aluminum (N) bilayers with a large resistivity ratio,...     

Isatin Derivatives Containing Sterically Hindered Phenolic Fragment and Water-Soluble Acyl Hydrazones on Their Basis: Synthesis and Antimicrobial Activity

Condensation reactions of isatin derivatives with 3,5-di(tert-butyl)-4-hydroxybenzyl acetate and the Girard’s reagent T has afforded a series of novel water-soluble isatin-3-acyl hydrazones containing a sterically hindered phenolic fragment in position 1 of the heterocycle; antimicrobial activity of the products has been estimated. It has been shown that the isatin derivatives with bromine or methoxy substituent in the benzo fragment as well as the acyl hydrazones containing 5-methyl or 5-ethyl group are the most active against Staphylococcus aureus and Bacillus cereus.     

An efficient method for the N-arylation of phenylurea via copper catalyzed amidation

The coupling reaction of phenylurea with different functionalized aryl halides in the presence of air stable CuI,N,N-dimethylethylenediamine as a ligand,and K₃PO₄ as a base gives symmetrical and unsymmetrical diarylureas in relatively high yields.This method is milder than the palladium catalyzed arylation and avoids the use of toxic phosphine ligands.     

Synthesis of novel “hybrid” structures based on phosphorylacetic acid hydrazides and sterically hindered phenols

Abstract

The insertion of fragments of sterically hindered phenols into the structure of phosphorylacetic acids hydrazides in their reactions with 3,5-di-tert-butyl-4-hydroxybenzylacetates and sterically hindered 2- and 4-hydroxybenzaldehydes has been carried out. The synthesis of 3,5-di-tert-butyl-4-benzyl derivatives of 5-[(diphenylphosphoryl) methyl]-2,4-dihydro-3H-1,2,4-triazol-3-thiones was also carried out.