Numerical analyses of flow around airfoils subjected to flow induced vibration

This paper describes extensive computer-based analytical studies on the details of unsteady flow behavior around airfoils subjected to flow induced vibration in turbo-machinery. To consider the time-dependent motions of airfoils, a complete Navier-Stokes solver incorporating a moving mesh based on an analytic solution of motion equation for airfoil translation and rotation was applied. The drag and lift coefficients for the cases of stationary airfoils and airfoils subjected to flow induced vibration were examined. From the numerical results in non-coupling case as out of consideration of the airfoil motion, it was found that the separation vortex consisted of large-scale rolls with axes in the span direction, and rib substructures with axes in the stream direction. In the coupling simulation including the airfoil motion, both the translation and the rotation displacement were gradually increased when the airfoil translation and rotation natural frequencies synchronize exactly with the oscillation frequency of the fluid force. In addition, the transformation from complex structure with rolls and ribs to two-dimensional aspect of only rolls could be visualized in three-dimensional simulation.     

Calculation of CWKB envelope in boson and fermion productions

We present the calculation of envelope of boson and of both low-and high-mass fermion production at the end of inflation when the coherently oscillating inflatons decay into bosons and fermions. We consider three different models of inflation and use CWKB technique to calculate the envelope to understand the structure of resonance band formation. We observe that though low-mass fermion production is not effective in preheating because of Pauli blocking, it is quite probable for high-mass fermion to take part in pre-heating.      

Propagation of arbitrary initial wave packets in a quantum parametric oscillator: Instability zones for higher order moments

We consider the dynamics of a particle in a parametric oscillator with a view to exploring any quantum feature of the initial wave packet that shows divergent (in time) behaviour for parameter values where the classical motion dynamics of the mean position is bounded. We use Ehrenfest's theorem to explore the dynamics of nth order moment which reduces exactly to a linear non autonomous differential equation of order $n+1$. It is found that while the width and skewness of the packet is unbounded exactly in the zones where the classical motion is unbounded, the kurtosis of an initially non-gaussian wave packet can become infinitely large in certain additional zones. This implies that the shape of the wave packet can change drastically with time in these zones.     

Thermodynamics of Lema$$\hat{i}$$ tre−Tolman−Bondi Model

Here we consider our universe as inhomogeneous spherically symmetric Lema [^(i)]{\hat{i}} tre−Tolman−Bondi Model and analyze the thermodynamics of this model of the universe. The trapping horizon is calculated and is found to coincide with the apparent horizon. The Einstein field equations are shown to be equivalent with the unified first law of thermodynamics. Finally assuming the first law of thermodynamics validity of the generalized second law of thermodynamics is examined at the apparent horizon for the perfect fluid and at the event horizon for holographic dark energy.     

Evaluation of methods for measuring amino acid hydrophobicities and interactions

The concept of hydrophobicity has been addressed by researchers in all aspects of science, particularly in the fields of biology and chemistry. Over the past several decades, the study of the hydrophobicity of biomolecules, particularly amino acids has resulted in the development of a variety of hydrophobicity scales. In this review, we discuss the various methods of measuring amino acid hydrophobicity and provide explanations for the wide range of rankings that exist among these published scales. A discussion of the literature on amino acid interactions is also presented. Only a surprisingly small number of papers exist in this rather important area of research; measuring pairwise amino acid interactions will aid in understanding structural aspects of proteins.     

Chlorin e6 Derivative Radachlorin Mainly Accumulates in Mitochondria,Lysosome and Endoplasmic Reticulum and Shows High Affinity toward Tumors in Nude Mice in Photodynamic Therapy

The efficacy of photodynamic therapy (PDT) depends upon the amount of photosensitizer accumulated in the malignant tissues. Radachlorin is a popular photosensitizer used in photodynamic therapy to treat various types of cancer. In this study, we have studied the main organelles responsible for the accumulation of radachlorin in human anaplastic thyroid cancer in vitro and in vivo. The optimal time window for uptake and clearance of radachlorin also was studied. Confocal microscopic images confirmed that the radachlorin is mainly acquired by mitochondria and partially by lysosome and endoplasmic reticulum. Studies also showed that the maximum amount of radachlorin was accumulated within 3–6 h after the treatment. Radachlorin also showed a higher affinity toward malignant tumors compared to the other organs in mice xenograft model. Uptake of radachlorin reached an optimum amount within 6 h and most of the radachlorins were also cleared from the body in next 48 h. Therefore, detailed information regarding exact accumulation sites and a time window in which maximum amount of drug is accumulated and cleared were obtained by this study. Hence, not only the efficacy of the treatment can be increased but the phototoxicity after the treatment also can be controlled.