Optimized Extraction of Artemisinin from Artemisia annua L. and Corroborated Quantitative Analysis Using High-Performance Thin-Layer Chromatography

JPC – Journal of Planar Chromatography – Modern TLC - An optimized method for the extraction and quantification of artemisinin using high-performance thin-layer chromatography (HPTLC)...     

Iron Oxide Supported on Al2O3 Catalyst for Methane Decomposition Reaction: Effect of MgO Additive and Calcination Temperature

Production of hydrogen is a challenging task and have significant impact in the recent scenario. The alumina supported iron oxide nanoparticle synthesized using non‐ionic surfactant Triton‐X was found very effective for steady production of hydrogen through methane decomposition reaction. The high surface area, easily reducible catalyst calcined at 500 °C and 800 °C temperature showed steady activity towards methane decomposition reaction. At a higher reaction temperature there was catalyst deactivation. The doping of MgO facilitated particle growth rendering the poor catalytic activity. The TPR study showed that reducibility of TPR was difficult in presence of MgO additive. The formation of Fe? Mg? Al solid solution confirmed by XRD study was found mainly responsible for the lower catalytic activity. The bamboo‐shaped carbon nanotube formed from 20 % Fe/Al₂O₃ catalyst which is mainly because of the poor wetting property of quasi‐liquid metal and carbon nanotube.     

Interaction of surface water waves with a vertical elastic plate: a hypersingular integral equation approach

In this paper, we present an alternative method to investigate scattering of water waves by a submerged thin vertical elastic plate in the context of linear theory. The plate is submerged either in deep water or in the water of uniform finite depth. Using the condition on the plate, together with the end conditions, the derivative of the velocity potential in the direction of normal to the plate is expressed in terms of a Green’s function. This expression is compared with that obtained by employing Green’s integral theorem to the scattered velocity potential and the Green’s function for the fluid region. This produces a hypersingular integral equation of the first kind in the difference in potential across the plate. The reflection coefficients are computed using the solution of the hypersingular integral equation. We find good agreement when the results for these quantities are compared with those for a vertical elastic plate and submerged and partially immersed rigid plates. New results for the hydrodynamic force on the plate, the shear stress and the shear strain of the vertical elastic plate are also evaluated and represented graphically.     

BRST symmetry for Regge–Teitelboim-based minisuperspace models

The Einstein–Hilbert action in the context of higher derivative theories is considered for finding their BRST symmetries. Being a constraint system, the model is transformed in the minisuperspace language with the FRLW background and the gauge symmetries are explored. Exploiting the first order formalism developed by Banerjee et al. the diffeomorphism symmetry is extracted. From the general form of the gauge transformations of the field, the analogous BRST transformations are calculated. The effective Lagrangian is constructed by considering two gauge-fixing conditions. Further, the BRST (conserved) charge is computed, which plays an important role in defining the physical states from the total Hilbert space of states. The finite field-dependent BRST formulation is also studied in this context where the Jacobian for the functional measure is illustrated specifically.     

A short and efficient synthesis of 5-hydroxymethylcyclopent-2-enol from d-glucose and its elaboration to the carbanucleoside (−)-carbovir

Introduction of an allyl functionality at C-3 of 1,2:5,6-di-O-isopropylidene-α-d-glucofuranose followed by olefination at C-5 and C-6 provided 1,6-diene 5 which, upon ring closing metathesis and subsequent functional group manipulation, furnished the key cyclopentene diacetate 7, which was elaborated to carbanucleoside (−)-carbovir 1.     

Nonlinear Dispersive and Dissipative Electrostatic Structures in Two-Dimensional Electron-Positron-Ion Quantum Plasma

The nonlinear features of two-dimensional ion acoustic(IA) solitary and shock structures in a dissipative electron-positron-ion(EPI) quantum plasma are investigated. The dissipation in the system is taken into account by incorporating the kinematic viscosity of ions in plasmas. A quantum hydrodynamic(QHD) model is used to describe the quantum plasma system. The propagation of small but finite amplitude solitons and shocks is governed by the Kadomtsev-Petviashvili-Burger(KPB) equation. It is observed that depending on the values of plasma parameters(viz.quantum diffraction, positron concentration, viscosity), both compressive and rarefactive solitons and shocks are found to exist. Furthermore, the energy of the soliton is computed and possible solutions of the KPB equation are presented numerically in terms of the monotonic and oscillatory shock profiles     

Mitigation of edgewise vibrations in wind turbine blades by means of roller dampers

Edgewise vibrations in wind turbine blades are lightly damped, and large amplitude vibrations induced by the turbulence may significantly shorten the fatigue life of the blade. This paper investigates the performance of roller dampers for mitigation of edgewise vibrations in rotating wind turbine blades. Normally, the centrifugal acceleration of the rotating blade can reach to a magnitude of 7–8g, which makes it possible to use this kind of damper with a relatively small mass ratio for suppressing edgewise vibrations effectively. The parameters of the damper to be optimized are the mass ratio, the frequency ratio, the coefficient of rolling friction and the position of the damper in the blade. The optimization of these parameters has been carried out on a reduced 2-DOF nonlinear model of the rotating wind turbine blade equipped with a roller damper in terms of a ball or a cylinder, ignoring the coupling with other degrees of freedom of the wind turbine. The edgewise modal loading on the blade has been calculated from a more sophisticated 13-DOF aeroelastic wind turbine model with due consideration to the indicated couplings, the turbulence and the aerodynamic damping. Various turbulence intensities and mean wind speeds have been considered to evaluate the effectiveness of the roller damper in reducing edgewise vibrations when the working conditions of the wind turbine are changed. Further, the optimized roller damper is incorporated into the 13-DOF wind turbine model to verify the application of the decoupled optimization. The results indicate that the proposed damper can effectively improve the structural response of wind turbine blades.     

Design,synthesis, preliminary pharmacological evaluation,and docking studies of pyrazoline derivatives

Ten derivatives of N1 substituted/unsubstituted 5-(4-chlorophenyl)-3-(2-thienyl) pyrazoline were synthesised from chalcone-like intermediate and substituted phenyl hydrazines, hydrazine hydrate, and semi/thiosemicarbazide. The chemical structure of compounds was confirmed by means of IR, ¹H NMR, mass spectroscopy, and elemental analysis. The antidepressant and anticonvulsant activities were investigated by Porsolt’s behavioural despair test (forced swimming) and maximum electroshock seizure test, respectively. Rota-Rod test was performed to assess any probable changes in motor coordination induced by the test compounds. Four compounds (IId, IIg, IIi, and IIj) exhibited good activity profile against depression and docking studies confirmed their consensual interaction with monoamine oxidase A. In addition, compounds IIc and IIe showed protection against MES-induced seizures.