全文获取类型
收费全文 | 21944篇 |
免费 | 821篇 |
国内免费 | 9篇 |
专业分类
化学 | 14496篇 |
晶体学 | 160篇 |
力学 | 367篇 |
数学 | 3722篇 |
物理学 | 4029篇 |
出版年
2023年 | 147篇 |
2022年 | 126篇 |
2021年 | 212篇 |
2020年 | 325篇 |
2019年 | 333篇 |
2018年 | 463篇 |
2017年 | 408篇 |
2016年 | 831篇 |
2015年 | 645篇 |
2014年 | 674篇 |
2013年 | 1449篇 |
2012年 | 1416篇 |
2011年 | 1392篇 |
2010年 | 830篇 |
2009年 | 763篇 |
2008年 | 1226篇 |
2007年 | 1262篇 |
2006年 | 1123篇 |
2005年 | 1047篇 |
2004年 | 955篇 |
2003年 | 734篇 |
2002年 | 642篇 |
2001年 | 491篇 |
2000年 | 445篇 |
1999年 | 329篇 |
1998年 | 227篇 |
1997年 | 217篇 |
1996年 | 286篇 |
1995年 | 201篇 |
1994年 | 229篇 |
1993年 | 190篇 |
1992年 | 195篇 |
1991年 | 178篇 |
1990年 | 172篇 |
1989年 | 152篇 |
1988年 | 141篇 |
1987年 | 134篇 |
1986年 | 136篇 |
1985年 | 198篇 |
1984年 | 195篇 |
1983年 | 124篇 |
1982年 | 129篇 |
1981年 | 142篇 |
1980年 | 137篇 |
1979年 | 98篇 |
1978年 | 96篇 |
1977年 | 105篇 |
1976年 | 83篇 |
1975年 | 88篇 |
1973年 | 71篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
971.
Vera C.M. Duarte Hélio Faustino Maria J. Alves António Gil Fortes Nuno Micaelo 《Tetrahedron: Asymmetry》2013,24(18):1063-1068
Two d-erythrose 1,3-butadienes were reacted with electrophilic achiral t-butyl 2H-azirine 3-carboxylate giving cycloadducts with good yields and moderate selectivity. The isomers could be separated to give the major (R)-isomers at C-2 in approximately 50% yield in both cases. Alternatively LACASA-DA methodology was applied to one of the reactions leading to homochiral (R)- and (S)-products by changing the chiral nature of an extra chiral BINOL inductor used. 相似文献
972.
María Mar Quesada-Moreno Ana África Márquez-García Juan Ramón Avilés-Moreno Juan Jesús López-González 《Tetrahedron: Asymmetry》2013,24(24):1537-1547
The biological relevance of amino acids is well known. They can be used as zwitterionic, cationic or anionic forms according to the pH of the medium where they are. Thus, our aim herein was to study the conformational preference of the polar amino acid l-threonine [C4H9NO3, (2S,3R)-2-amino-3-hydroxybutyric acid] under different pH conditions. A conformational study in an aqueous solution of the dissociation equilibrium of the amino acid l-threonine was carried out for this purpose. We recorded, at room temperature, the Mid-IR, Far-IR, Raman and VCD spectra of l-threonine from the aqueous solutions at pH values 5.70 (zwitterionic species), 1.00 (protonated species) and 13.00 (deprotonated species). The number of conformers found with the conformational search was 9 zwitterions, 27 anions and 52 cations. Both the study of the conformational landscape and the theoretical analysis of the vibrational features were accomplished by using DFT and ab initio calculations, that is, B3LYP/6-311++G(d,p) level of theory for all the conformers obtained from the conformational search, M062X/6-311++G(d,p) and MP2/6-311++G(d,p) levels of theory for the most stable conformers. The presence of water was included with the IEF-PCM implicit hydration model. With regard to the zwitterion, the importance of the analysis of the low frequency region (700–30 cm–1) in the Far-IR spectra should be noted, because it provides relevant information that can be used to determine the presence of the most stable structures. 相似文献
973.
Annamaria Varga Valentin Zaharia Mihály Nógrádi László Poppe 《Tetrahedron: Asymmetry》2013,24(21-22):1389-1394
Ethyl (S)-3-hydroxy-3-phenylpropionate (S)-2 was obtained by the asymmetric reduction of ethyl 3-phenyl-3-oxopropionate 1 with the yeast Saccharomyces cerevisiae (ATCC 9080). The kinetic resolution of racemic ethyl 2-acetoxy-3-phenyl-propionate rac-3 with the same microorganism, gave after hydrolysis ethyl (R)- and (S)-3-hydroxy-3-phenylpropionates (R)-2 and (S)-2 which were converted by a straightforward series of reactions to the enantiomers of 3-amino-3-phenyl-propionic acids (S)-6 and (R)-6. The asymmetric reduction and hydrolytic kinetic resolution were also tested with several other whole cell systems under a variety of conditions. 相似文献
974.
The enantiospecific syntheses of both enantiomers of bacillamide C and neobacillamide A are described, along with the measurement of their optical activities, leading to the revision of the proposed absolute configurations of these natural products. 相似文献
975.
976.
Carlos Conceição António 《Memetic Computing》2014,6(2):113-131
The mechanical properties of composite structures are sensitive to the choice of the material systems, the distribution of laminates on the structure, and the sizing at the laminate level. This sensitivity depends on many variables. To overcome the difficulties in attaining a global solution for the optimisation problem of composite structures, a new strategy is proposed based on the hybridisation of the memetic algorithm (MA) and the selfish gene (SG) algorithm. Instead of a local search, as performed in MAs, the selfish gene (SG) theory is applied, which follows a different learning scheme in which the conventional population of the individuals is replaced by a virtual population of alleles. The proposed approach, which is called the memetic-based selfish gene algorithm (MA + SG), is a mixed model that applies multiple learning procedures to explore the synergy of different cultural transmission rules in the evolutionary process. The principal aspects of the approach are as follows: co-evolution of multiple populations, species conservation, migration rules, self-adaptive multiple crossovers, local search in hybrid crossover with local genetic improvements, controlled mutation, individual age control, and feature-based allele statistical analysis. To discuss the capabilities of the proposed approach, numerical examples are represented to compare the results of MA + SG with those obtained using genetic algorithms (GA) and MA. The numerical results of the comparison tests showed that the GA and the MA maintained long periods without the evolution of the best-fitted individual/solutions. This behaviour during evolution is associated with the slow maturation of the elite group of populations in the GA and MA approaches. This behaviour is avoided when the MA + SG proposed approach is used with computational cost benefits. 相似文献
977.
Dr. Paula Gómez‐Álvarez Prof. Sofia Calero 《Chemistry (Weinheim an der Bergstrasse, Germany)》2016,22(52):18705-18708
The separation of carbon dioxide from flue gas is essential for the reduction of greenhouse gas emissions. In adsorptive methods, the challenge lies in the choice of suitable porous materials. Among all zeolite topologies, a number of adsorbents with pore dimensions in the range of the guest molecules were identified to allow an excellent separation by diffusion, and MRE and AFO zeolite topologies appear to be the best candidates based on equilibrium adsorption. Also, it was found that the behavior of this gas mixture in DFT and APD zeolites differed from the normal behavior. 相似文献
978.
979.
980.