Reactions of 1-Allenylpyrazole and 1-Allenyl-1,2,4-triazole with Hydrogen Chloride and Metal Chlorides

1-Allenylpyrazole and 1-allenyl-1,2,4-triazole react with hydrogen chloride via proton addition at the pyridine-like nitrogen atom (N² and N⁴, respectively). In the reaction with 1-allenylpyrazole, 1-[(E)-3-chloro-1-propenyl]pyrazole is also formed via regio- and stereoselective addition of hydrogen chloride to the propadienyl group. 1-Allenylpyrazole and 1-allenyl-1,2,4-triazole act as unidentate ligands with respect to Co, Ni, Cu, Zn, Cd, Pd, and Sn, the donor centers being N² and N⁴, respectively. Apart from mononuclear coordination compounds, 1-allenylpyrazole gives rise to polymeric complexes which contain units and blocks formed by the free ligand.     

Atomic spectroscopy for detection in thermal analysis

An atomic absorption spectrophotometer is coupled to a conventional thermoanalytical quartz furnace as used for TG and DTG to detect the thermally evolved products. In this combined system, the dry aerosol (smoke) obtained by cooling the vapour evolved is transported from the furnace to the flame for metal-specific atomic absorption detection. The particular design of the furnace outlet promotes the formation of stable aerosols. Optimum experimental conditions were determined, using zinc chloride solution, by varying the specimen mass, the heating rate and the flow rate of the furnace gas at a linear temperature program. The absorbancevs. temperature curves obtained with this method for various zinc compounds are compared with the corresponding DTG curves. The applicability of the technique for studying heterogeneous reactions with carbon tetrachloride and hexane vapours is presented. The utilization of an atomic absorption spectrophotometer equipped with a quartz cuvette for detecting the thermal evolution of mercury vapours is described, as well as detection potentials by molecular absorption (for NO and NH₃) and light scattering (for smoke evolved from organic matter). The results obtained with the suggested methods may, in some respects, valuably complement the results achieved with DTG and with flame ionization detection.

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Zusammenfassung Ein Atomabsorptionsspektrometer wurde mit einem konventionellen thermoanalytischen Quarzofen gekoppelt um thermische Abspaltprodukte nachzuweisen. In diesem kombinierten System wird das durch Kühlung des entwickelten Dampfes erhaltene Aerosol (Rauch) vom Ofen in die Flamme für den metallspezifischen Atomabsorptionsnachweis übergeleitet. Die spezielle Ausbildung der Austrittsöffnung gewährleistet die Bildung eines stabilen Aerosols. Die optimalen Versuchsbedingungen wurden durch Zinkchloridlösungen bei Anderung der Probenmasse, der Aufheizgeschwindigkeit und der Strömungsgeschwindigkeit des Ofengases im linearen Temperaturprogramm ermittelt. Die mit dieser Methode für verschiedene Zinkverbindungen erhaltenen Absorptions—Temperatur-Kurven wurden mit den entsprechenden DTG-Kurven verglichen. Die Anwendbarkeit dieser Technik bei dem Studium heterogener Reaktionen mit Kohlenstofftetrachlorid und Hexandämpfen wird gezeigt. Der Einsatz eines mit einer Quarzküvette zum Nachweis der thermischen Entwicklung von Quecksilberdampf versehenen Atomabsorptionsspektrometers wird beschrieben, sowie die Nachweisgrenze durch molekulare Absorption (für NO und NH₃) und Lichtstreuung (für aus organischem Material entwickelten Rauch). Die bei den beschriebenen Methoden erhaltenen Ergebnisse können, in mancher Hinsicht, die durch DTG und Flammenionisationsnachweis erhaltenen Ergebnisse wertvoll ergänzen.

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- , , . (), , . . , . — , , -. . - , , , ( NO NH₃) ( , ). , , , - .

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Presented in part at the 24th Hungarian Conference on Analytical Sptecroscopy, Miskolc, June 15–18, 1981. Abstracts pp. 159–162.

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The authors wish to express their thanks to S. Gál for his assistance in the present application of the temperature programmer developed by him and his group, and for the valuable discussions on the subject. Thanks are also due to K. Tomor and J. Kmives who participated in the comparative thermoanalytical measurements and their analysis.     

Improvements to the distance geometry algorithm for conformational sampling of cyclic structures

Modifications to the distance geometry algorithm as embodied in the program DGEOM have been made to improve sampling capabilities. Specifically, torsion angle sampling replaces distance sampling for 1,4 atomic relationships and correlated distance sampling is disabled. The effects of these modifications are illustrated by comparing the different sets of conformations produced for butane. In addition, these changes are shown to increase the conformational sampling of two medium-sized rings, cycloheptadecane and caprylolactam. The current results for these molecules are compared to those of other conformational searching methods.     

Benzindoles. 23. 2-formyl- and 3-formyl-4,5-benzindoles

It is shown that, in addition to the usually formed 3-formyl-4,5-benzindole, 2-formyl-4,5-benzindole can be obtained via the Vilsmeier reaction. The IR, PMR, and UV spectra of the 2- and 3-formyl isomers are compared, and their possible conformations are discussed.See [1] for Communication 22.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 343–345, March, 1984.     

Mass-spectrometric determination of metal chelates

Zusammenfassung Aus digitalisierten Raman- und Infrarotspekten von 70 Steroiden wurden die Summenspektren der Substanzen mit übereinstimmenden Strukturmerkmalen berechnet. In diesen Spektren sind Banden geringer Standardabweichung dann charakteristisch für ein Strukturmerkmal, wenn sie bei anderen Strukturmerkmalen fehlen. Sie sind dann für die Strukturaufklärung von Substanzen unbekannter Struktur geeignet.

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Raman spectroscopy and molecular structureIII. Selection of characteristic bands of polyatomic molecules by means of a computer

Digitized Raman and infrared spectra of 70 steroids are used for the calculation of summarized spectra of all substances with the same structural details. In these spectra bands with low standard deviation are characteristic for the structural detail if they are absent in the other groups of spectra. They can be used for the elucidation of unknown structures.

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Wir danken Herrn Dipl.-Phys. H. Barentzen für die Aufstellung des Computerprogramms sowie Frl. G. Pannek und Frau E. von Bühlow für die Hilfe bei der Verschlüsselung und Aufbereitung der Daten. — Der Deutschen Forschungsgemeinschaft und dem Landesamt für Forschung, Nordrhein-Westfalen, danken wir für Sachbeihilfen.     

Application of Molecular Weight and Particle Growth Measurements in Continuously Uniform Latices to Kinetic Studies of Styrene Emulsion Polymerization

It is possible to generate, in specially formulated styrene emulsion polymerizations, latices in which the monomer—polymer particles are uniform through all stages of growth. These latices are kinetically similar to their polydispersed counterparts and can therefore be used as model systems in generalized kinetic studies of emulsion polymerization. The most important feature of these systems is the fact that the particles are uniform throughout the reaction with regard to all intrinsic properties and rate processes, and the particles can be characterized by this complete, continuous uniformity. Certain remarkably simple, but precise, relationships exist between the overall, measurable kinetic parameters and the individual particle kinetic parameters, thereby resulting in a heretofore unrealized analytic accessibility. Molecular weight kinetic analyses are an order of magnitude more accurate than in non-uniform systems. Application of these continuously uniform systems in actual kinetic studies indicates an inconsistency in the current concepts of emulsion polymerization, i.e., the generation of polymer at a constant molecular weight is predicted while an increase of several fold is observed. Before the situation can be clarified, further studies with continuously uniform systems are needed to evaluate molecular weight development, molecular weight distribution, and molecular structure and also to re-evaluate the rate and diffusion processes which control these structural features.     

Emission studies of pyrene solutions

Emission spectra of pyrene in hexane have been obtained over a temperature range (from 130 to 260 K) that has not been explored before for concentrations ranging from 10^?4 mole/? to 2 × 10^?2 mole/?. A conventional and new approximation which does not depend on the experimental set-up response functions has been used for evaluating pyrene excimer association energy W_DM and other pyrene parameters. In both methods W_DM agrees quite satisfactorlly, at all concentrations used, with that reported in the literature and obtained by other techniques. However, both approximation fail to yield the right values of the rate parameters at concentrations ? 2 g/?. This set the upper limit of sample solubility to be at C = 2g/? for our range of temperature. Furthermore, the new approximation can probably be used at higher concentration (for higher range of temperature) and even may be used for other organic molecules. There was also no difference in the ratio of the excimer (I_D) to monomer (I_M) quantum yields when an intense laser beam was used as a source of excitation rather than a super-pressure Hg-lamp. This suggested that the concentrations we used might not be large enough. As a result, the laser beam would not create enough density of excited molecules to affect the ratio of I_D/I_M.     

A study of solar erythema radiation doses

Abstract —Using semi-empirical analytic formulas for the transmitted and scattered ultraviolet spectral irradiance at the ground (Green, A. E. S., T. Sawada and E. P. Shettle, Photochem. Photobiol. 19 , 251–259, 1974), we calculate erythema dose rates and daily erythema doses. Results are illustrated graphically, and for the purpose of photobiological applications are given in terms of approximate analytic forms, with parameters presented in tabular form. The relative erythema data assembled by W. W. Coblentz and R. Stair (U.S. Bureau of Standards J. Res. 12 , 13–14, 1934), as fit by an analytic form, is taken as a standard spectrum in our calculations. Other forms of erythema spectra are also compared.     

Chlorination of α-sulfonyl carbanions with hexachloroethane: A novel preparation of α-halosulfones

The cyclic sulfones1,2, and3 are lithiated in benzene with n-butyllithium. Lithiation is demonstrated to lead to α-mono, α,α′-di and/or α,α-di and α,α,α′ trimetallation. The lithiated sulfones are chlorinated with hexachloroethane (HCE). Some mechanistic aspects of the reaction of the lithiosulfones with vicinal dihalides are discussed.     

Eine neue Methode zur Ermittlung der Zusammensetzung schwacher Komplexe

Zusammenfassung Die Zusammensetzung schwacher Komplexe der Form AB _n — wobei n auch ein Bruch sein kann — läßt sich mit den heute üblichen Methoden nur ungenau oder sogar überhaupt nicht ermitteln. Es wird eine neue Methode beschrieben, bei der zu einer konstanten Menge der Komponente A steigende Mengen der Komponente B hinzugesetzt werden und eine, der Menge des gebildeten Komplexes AB _n proportionale Größe beobachtet wird. Aus den Meßwerten werden bestimmte Funktionen gebildet, die in einem passend gewählten Koordinatensystem nur dann als gerade Linien erscheinen, wenn ein Parameter identisch mit dem Werte n ist.Es werden Beispiele für die Ermittlung der Zusammensetzungsverhältnisse 11, 12 und 13 gebracht.Die Methode ist nicht nur bei schwachen Komplexen, sondern auch bei stärker dissoziierten Verbindungen anwendbar. Auch die Koeffizienten einer Redoxgleichung lassen sich in speziellen Fällen auf diese Weise ermitteln.Für die Durchführung dieser Arbeit wurden dankenswerterweise Forschungsmittel aus dem ERP-Sondervermögen bereitgestellt.Dem Verbande der Chemischen Industrie und der Deutschen Forschungsgemeinschaft, die diese Arbeit unterstützt haben, danke ich bestens.