Interaction ofZ-1,2-borylphosphinoalkene with ketenimine

N-Phenyl-C,C-diphenylketenimine adds toZ-1-butyl-I-dibutylboryl-2-diphenylphosphino-2-phenylethene to give 2,2,3-tributyl-6-diphenylmethylideno-1,4,5,5-tetraphenyl-1-aza-5-phosphonia-2-borataeyclohex-3-ene, which rearranges into 4,6-dibutyl-2-diphenylphosphino-1,1,3,5-tetraplienyl-3-aza-4-boradeca-1,5-diene upon heating. Its crystal structure has been established by X-ray analysis.Deceased in 1995.Translated from IIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. l, pp. 183–187, January, 1996.     

Interaction of E-2-dibutylboryl-1-phenyl-1-diphenylphosphinohex-1-ene with diphenylketene and benzoyl(phenyl)diazomethane

A new betaine, 5,6,6-tributyl-2-diphenylmethylene-3,3,4-triphenyl-1-oxa-3-phosphonia-6-boratacyclohex-4-ene, and1-(benzoyl(phenyl)methyleneamino]-4,5,5-tributyl-2,2,3-triphenyl-2-phospha-I-azonia-5-boratacyclopenta-1,3-diene were synthesized upon interaction of E-2-dibutylboryl-1-phenyl-1-diphenylphosphinohex-1-ene with diphenylketene and benzoyl(phenyl)diazomethane, respectively. The structure of the latter product was established by IR spectroscopy and X-ray structural analysis.DeceasedTranslated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 2070–2074, August, 1996     

Synthesis of 3,4,6-borataoxaphosphoniacyclohexenes

Conclusions 1,12-Tributyl-3,4,4-triphenyl-1-borata-4-phosphoniacyclobutene-2 adds to aldehydes with formation of P and B containing heterocyclic compounds of a new type, 3,4,6-borataoxaphosphonia-cyclohexenes.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 1, pp. 163–165, January, 1988.     

Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence

Background  

Opioid agonist drugs produce analgesia. However, long-term exposure to opioid agonists may lead to opioid dependence. The analgesic and addictive properties of opioid agonist drugs are mediated primarily via the mu-opioid receptor (MOR). Opioid agonists appear to alter neuronal morphology in key brain regions implicated in the development of opioid dependence. However, the precise role of the MOR in the development of these neuronal alterations remains elusive. We hypothesize that identifying and characterizing novel MOR interacting proteins (MORIPs) may help to elucidate the underlying mechanisms involved in the development of opioid dependence.     

Complexes of Phosphorus-containing Cyclophanes and Cryptands with Metals,Anions, and Organic Substrates

Russian Journal of Organic Chemistry - New data since about 2010 concerning complex formation of phosphorus-containing cyclophanes and cryptands with transition metals, as well as guest-host...     

High precision delta(17)O isotope measurements of oxygen from silicates and other oxides: method and applications

The use of infrared laser-assisted fluorination to release oxygen from milligram quantities of silicates or other oxide mineral grains is a well-established technique. However, relatively few studies have reported the optimisation of this procedure for oxygen-17 isotope measurements. We describe here details of an analytical system using infrared (10 μm) laser-assisted fluorination, in conjunction with a dual inlet mass spectrometer of high resolving power ( approximately 250) to provide (17)O and (18)O oxygen isotope measurements from 0.5-2 mg of silicates or other oxide mineral grains. Respective precisions (1) of typically 0.08 and 0.04 per thousand are obtained for the complete analytical procedure. Departures from the mass-dependent oxygen isotope fractionation line are quantified by Delta(17)O; our precision (1) of such measurements on individual samples is shown to be +/-0.024 per thousand. In turn, this permits the offset between parallel, mass-dependent fractionation lines to be characterised to substantially greater precision than has been possible hitherto. Application of this system to investigate the (17)O versus (18)O relationship for numerous terrestrial whole-rock and mineral samples, of diverse geological origins and age, indicates that the complete data set may be described by a single, mass-dependent fractionation line of slope 0.5244+/- 0.00038 (standard error). Copyright 1999 John Wiley & Sons, Ltd.     

Test of bell’s inequality using the one-atom micromaser

We examine a local realist bound in the case of a one-atom micromaser. It is shown that such a bound is violated using a simplified treatment of the micromaser. We consider the effect of dissipation in a proposed experiment with the real micromaser. It is seen that the magnitude of violation of a Bell-type inequality depends significantly on the cavity parameters.     

Synthesis of New Phosphines and P-Heterocycles from Phosphonates Containing Allyl Group

Addition of phenylphosphine to allylphosphonate followed by reduction of the resulting diphosphonate gives a new branched phosphine, bis(3-phosphinopropyl)phenylphosphine. Its reaction with paraform and p-toluidine yields oligomeric 3-[3-(propylenophenylphosphino)propyl]-1,5-di-p-tolyl-1,5,3,7-diazadiphosphacyclooctane. Diethyl (5-allyl-2-ethoxybenzyl)phosphonate was obtained. Its reduction gives unsaturated (5-allyl-2-ethoxybenzyl)phosphine. This product adds two moles of formaldehyde to give bis(hydroxymethyl)(5-allyl-2-ethoxybenzyl)phosphine. The reaction of this compound with p-toluidine yielded, depending on the conditions, the corresponding bis(aminomethyl)phosphine, 1,3,5-diazaphosphorinane, and 1,5,3,7-diazadiphosphacyclooctane, and also their derivatives containing allyl substituents.