全文获取类型
收费全文 | 8500篇 |
免费 | 1731篇 |
国内免费 | 1989篇 |
专业分类
化学 | 6191篇 |
晶体学 | 257篇 |
力学 | 623篇 |
综合类 | 166篇 |
数学 | 994篇 |
物理学 | 3989篇 |
出版年
2024年 | 31篇 |
2023年 | 126篇 |
2022年 | 296篇 |
2021年 | 349篇 |
2020年 | 371篇 |
2019年 | 358篇 |
2018年 | 319篇 |
2017年 | 361篇 |
2016年 | 432篇 |
2015年 | 475篇 |
2014年 | 516篇 |
2013年 | 678篇 |
2012年 | 748篇 |
2011年 | 755篇 |
2010年 | 655篇 |
2009年 | 673篇 |
2008年 | 705篇 |
2007年 | 638篇 |
2006年 | 590篇 |
2005年 | 515篇 |
2004年 | 399篇 |
2003年 | 275篇 |
2002年 | 312篇 |
2001年 | 313篇 |
2000年 | 307篇 |
1999年 | 186篇 |
1998年 | 99篇 |
1997年 | 85篇 |
1996年 | 105篇 |
1995年 | 74篇 |
1994年 | 79篇 |
1993年 | 52篇 |
1992年 | 54篇 |
1991年 | 36篇 |
1990年 | 43篇 |
1989年 | 48篇 |
1988年 | 23篇 |
1987年 | 17篇 |
1986年 | 21篇 |
1985年 | 13篇 |
1984年 | 14篇 |
1983年 | 10篇 |
1982年 | 14篇 |
1981年 | 5篇 |
1980年 | 8篇 |
1979年 | 9篇 |
1978年 | 6篇 |
1977年 | 3篇 |
1971年 | 3篇 |
1965年 | 2篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
Ning Liu Shunzhong Luo Yuanyou Yang Taiming Zhang Jiannan Jin Jiali Liao 《Journal of Radioanalytical and Nuclear Chemistry》2002,252(1):187-191
The biosorption of radionuclide 241Am from solution by Saccharomyces cerevisiae (S. cerevisiae), and the effects of experimental conditions on the adsorption were investigated. The preliminary results showed thatS. cerevisiae is a very efficient biosorbent. An average of more than 99% of the total 241Am could be removed by S. cerevisiae of 2.1 g/l (dry weight) from 241Am solutions of 17.54–4386.0 mg/l (2.22 MBq/l–555 MBq/l) with adsorption capacities of 7.45–1880.0 mg/g biomass (dry weight) (0.94 MBq/g–237.9 MBq/g). The adsorption equilibrium was achieved within 1 hour and the optimum pH ranged 1–3. No significant differences on 241Am adsorption were observed at 10–45 °C, or in solutions containing Au3+ or Ag+, even 2000 times above 241Am concentration. The relationship between concentrations and adsorption capacities of 241Am indicated the biosorption process should be described by the Freundlich adsorption isotherm. 相似文献
22.
Synthesis of lipid A derivatives and their interactions with polymyxin B and polymyxin B nonapeptide 总被引:5,自引:0,他引:5
Yin N Marshall RL Matheson S Savage PB 《Journal of the American Chemical Society》2003,125(9):2426-2435
Lipid A is the causative agent of Gram-negative sepsis, a leading cause of mortality among hospitalized patients. Compounds that bind lipid A can limit its detrimental effects. Polymyxin B, a cationic peptide antibiotic, is one of the simplest molecules capable of selectively binding lipid A and may serve as a model for further development of lipid A binding agents. However, association of polymyxin B with lipid A is not fully understood, primarily due to the low solubility of lipid A in water and inhomogeneity of lipid A preparations. To better understand lipid A-polymyxin B interaction, pure lipid A derivatives were prepared with incrementally varied lipid chain lengths. These compounds proved to be more soluble in water than lipid A, with higher aggregation concentrations. Isothermal titration calorimetric studies of these lipid A derivatives with polymyxin B and polymyxin B nonapeptide indicate that binding stoichiometries (peptide to lipid A derivative) are less than 1 and that affinities of these binding partners correlate with the aggregation states of the lipid A derivatives. These studies also suggest that cooperative ionic interactions dominate association of polymyxin B and polymyxin B nonapeptide with lipid A. 相似文献
23.
合成子Ni替代铁酸稀土复合氧化物LaF31-xNixO3(x=0.1-0.6),对样品进行了XRD、IR及Mossbauer谱测试,结果表明:x=0\1,0\2,0\3的样品为正交相,x=0.5,0.6的样品为菱方相;伴随相结构从正交向菱方结构的转变,IR谱上Fe(Ni)-O键伸振动谱带向高频移动近20cm^-1,Mossbauer谱测试表明Fe均处于+3自旋态,Ni离子以+3价进入晶格。 相似文献
24.
Guoyi Bai Chenfang Zhang Yuecheng Zhang Haijun Yu Fei He Huisen Ning Ligong Chen 《Reaction Kinetics and Catalysis Letters》2007,90(2):373-380
The racemization of R-(-)-2-amino-1-butanol in a reaction using Co/γ-Al2O3 catalysts and catalysts modified by Mg or Ca was investigated in this paper. Complete racemization was achieved with a yield
of over 83% at using the Mg modified Co/γ-Al2O3 catalyst under optimized reaction conditions of 170°C and 2.5 MPa of H2. The catalysts were thoroughly characterized by XRD, XPS, TPR, SEM and TEM. The addition of Mg and Ca may be advantageous
for dispersing and stabilizing the active species of the Co/γ-Al2O3 catalyst, protecting from sintering, significantly improving its catalytic activity and stability. 相似文献
25.
1INTRODUCTIONRecentlyorganicnonlinearoptical(NLO)materialsarebeingdevelopedforfre-quencyconversionoflaserinopto-electrics-Especiallybluelightisrequiredforopti-calmemoryofhighdensityrecording.Becauseadiodelaserisusedasalightsource,thenonlinearmaterialswhichhaveextremelyhighvalueofNLOcoefficientsandthetransmissionofblueregionarenecessary.Sincethesecond-orderNLOpropertyoforganiccompoundisderivedfromconjugateddelocalizedrrelectrons,thecompoundswhichhavebeenreportedhavefocusedonthenitroanil… 相似文献
26.
27.
LI Rui ZHANG Duan-Ming HUANG Ming-Tao SU Xiang-Ying CHEN Zhi-Yuan ZHU Hong-Ying ZHANG Lin 《理论物理通讯》2007,48(8):343-347
We propose a two-dimensional model of polydisperse granular mixtures with a power-law size distribution in the presence of stochastic driving. A fractal dimension D is introduced as a measurement of the inhomogeneity of the size distribution of particles. We define the global and partial granular temperatures of the multi-component mixture. By direct simulation Monte Carlo, we investigate how the inhomogeneity of the size distribution influences the dynamic properties of the mixture, focusing on the granular temperature, dissipated energy, velocity distribution, spatial clusterization, and collision time. We get the following results: a single granular temperature does not characterize a multi-component mixture and each species attains its own "granular temperature"; The velocity deviation from Gaussian distribution becomes more and more pronounced and the partial density of the assembly is more inhomogeneous with the increasing value of the fractal dimension D; The global granular temperature decreases and average dissipated energy per particle increases as the value of D augments. 相似文献
28.
汽车车轮流场的数值模拟 总被引:1,自引:1,他引:0
首先以独立车轮为研究对象,以商用计算流体力学软件STAR—CD为工具,利用移动边界条件,并依据k-ε双方程高雷诺数湍流模型对三维定常不可压缩流N-S方程进行数值模拟计算.然后在合适尺寸的计算域下对3种不同宽度的静止和滚动车轮分别进行数值模拟计算,研究车轮宽度和来流速度对阻力系数的影响,将计算结果与实验结果进行了对比分析.计算结果表明,车轮宽度的减小以及来流速度的减小均明显降低汽车的气动阻力系数. 相似文献
29.
Jing-Yuan Chang Yen-Jin Pan Pei-Yu Huang Yi-Ting Sun Chen-Hsu Yu Zhi-Jun Ning Shou-Ling Huang Shing-Jong Huang Richard P. Cheng 《Molecules (Basel, Switzerland)》2022,27(13)
The β-sheet is one of the common protein secondary structures, and the aberrant aggregation of β-sheets is implicated in various neurodegenerative diseases. Cross-strand interactions are an important determinant of β-sheet stability. Accordingly, both diagonal and lateral cross-strand interactions have been studied. Surprisingly, diagonal cross-strand ion-pairing interactions have yet to be investigated. Herein, we present a systematic study on the effects of charged amino acid side-chain length on a diagonal ion-pairing interaction between carboxylate- and ammonium-containing residues in a β-hairpin. To this end, 2D-NMR was used to investigate the conformation of the peptides. The fraction folded population and the folding free energy were derived from the chemical shift data. The fraction folded population for these peptides with potential diagonal ion pairs was mostly lower compared to the corresponding peptide with a potential lateral ion pair. The diagonal ion-pairing interaction energy was derived using double mutant cycle analysis. The Asp2-Dab9 (Asp: one methylene; Dab: two methylenes) interaction was the most stabilizing (−0.79 ± 0.14 kcal/mol), most likely representing an optimal balance between the entropic penalty to enable the ion-pairing interaction and the number of side-chain conformations that can accommodate the interaction. These results should be useful for designing β-sheet containing molecular entities for various applications. 相似文献
30.