SYNTHESES AND PROPERTIES OF POLYPHENYL-1,2,4-TRIAZINES

A series of aromatic poly--1, 2, 4-triazines have been prepared. Experimental results showedthat these polymers exhibited good thermally oxidative stability as determined by isothermal agingat 30℃for 200 hours in air. After submerging the coated wire in boiling water for 240 hours nochange in electrical insulation was detected. Polymer films also showed good tensile strength (1050-1400 kg/cm~2) at room temperature. Therefore aromatic poly-1, 2, 4-triazines demonstrate highperformance showing good potential for use as functional and structural resins in the environmentsdemanding high thermal stability and hydrolytic stability.     

O~6-METHYLGUANINE-DNA METHYLTRANSFERASE AND HUMAN CANCER CHEMOTHERAPY

Two kinds of human tumor cell strains having different activity of O~6-methylguanine-DNA methyltransferase (O~6-MT) were transplanted into nude mice. Then the mice were inject-ed intraperitoneally with bifunctional alkylating agent 1--(4--amino--2-methyl--5--pyrimidinyl)methy1-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU). The tumors with low O~6-MTactivity were quickly suppressed or cured. The result suggests that some tumors, if previ-sionally determined with low O~6-MT activity, might be efficiently cured by treatment withACNU. This probably opens a new way for human cancer chemotherapy.     

绿色化学实验

绿色化学实验的研究和设计将实现对环境没有或只有很少负作用的理想与目标 ,微型实验、小量 -半微量实验、微波化学实验和计算机辅助的绿色化学实验设计是实现这一目标的一些可能途径。     

神木煤有机显微组分的结构特征与热转化性质的关系

通过手选和重液浮选分离相结合的方法，从神木煤中分离得到了纯度较高的镜质组和惰质组，并对其进行元素分析、FT-IR、13CNMR和TG/DTG等表征分析。结果表明，神木煤镜质组和惰质组的最佳分离密度为1.320 g/cm3～1.324 g/cm3和1.378 g/cm3～1.382 g/cm3，此时分离纯度分别为97.55%和96.90%。镜质组有较高的H含量，较低的芳香度0.51和数量较多的氢键；惰质组有较高的碳含量，较高的芳香度0.76，原煤的芳香度介于两者之间为0.68。FT-IR分析表明，镜质组比惰质组有较多的氢键，脂肪氢含量和较少的Har/Hal比。随温度增加，镜质组和惰质组的芳香氢含量和Har/Hal比增加，而脂肪氢含量减少。相同温度下，惰质组的Har/Hal比始终高于镜质组。TG/DTG分析表明惰质组比镜质组有较高的热稳定性，原煤的热稳定性介于两者之间，在相同的Har/Hal比时镜质组中剩余挥发分比惰质组的少，反映出惰质组的组成（较高的芳香度和较低的脂肪氢含量）对热稳定性的影响。     

An Unexpected Discovery in the Willgerodt-Kindler Reaction of Acetophenone——the Formation of the 4-（Benzoylthiocarbonyl）morpholine

The Willgerodt-Kindler reaction of acetophenone was studied.Apart from the normal product 4-(benzylthio-carbonyl)morpholine,another product 4-(benzoylthiocarbonyl)morpholine was obtained unexpectedly.The struc-ture of the latter was confirmed by IR,~1H NMR spectra and X-ray diffraction analysis.The mechanism of the reac-tion was discussed.     

SrAl_2O_4∶Eu~(2 ),Dy~(3 )纳米长余辉发光材料的制备与表征

采用溶胶鄄凝胶法制备了SrAl2O4∶Eu2 ,Dy3 纳米长余辉发光材料,研究了pH值、反应温度和络合剂等对溶胶鄄凝胶形成的影响,研究了灼烧温度对SrAl2O4∶Eu2 ,Dy3 晶相、颗粒尺度和发光性能的影响。利用XRD,SEM,光谱分析等手段对产物进行了结构和性能分析。实验结果表明,在800℃时SrAl2O4晶相开始形成但没有发光,而在1100℃烧结的样品则具有很好的发光性能。样品平均晶粒尺寸随灼烧温度升高而增加,平均晶粒尺寸为20~40nm。样品的激发光谱是峰值在240,330,378和425nm的连续宽带谱,发光光谱是峰值在523nm的宽带谱,与SrAl2O4∶Eu2 ,Dy3 粗晶材料相比,发光光谱发生了“红移”现象。样品的热释光峰值位于157℃,与SrAl2O4∶Eu2 ,Dy3 粗晶材料相比,峰值向低温移动了13℃。     

无溶剂无催化剂微波促进下 1-苯基-3-甲基-5-吡唑啉酮与芳醛的反应研究

无溶剂无催化剂条件下,微波促进1-苯基-3-甲基-5-吡唑啉酮与芳醛的缩合反应选择不同辐射功率将分别得到4-芳亚甲基-3-甲基-1-苯基-5-吡唑啉酮和4,4′-芳亚甲基-双(1-苯基-3-甲基-5-吡唑啉酮),产率良好.产物结构经1H NMR,13CNMR和IR进行了表征.     

新型三环系稠杂环［1,2,4］-三唑并［1,5-a］［1］-苯并氮杂及［1,2,4］-三唑并［1,5-a］-喹啉的合成

α-四氢萘酮的乙氧羰基腙(1)经LTA氧化, 得到α-偶氮-α-乙酰氧基化合物2. 在AlCl3作用下, 化合物2脱去乙酰氧基产生重氮正离子中间体3, 再经与腈的1,3-偶极环加成、 ［1,2］-迁移扩环、 碱性水解和与苦味酸作用, 得到新型［1,2,4］-三唑并［1,5 a］［1］苯并氮杂苦味酸盐6a~6c. 以2,3-二氢-1-茚酮为底物, 采用相同的合成路线, 合成了1,2,4-三唑并［1,5-a］-二氢喹啉苦味酸盐12a~12c.     

2,9,16,23-四联苯基金属酞菁的合成、溶解性及光学性质

合成了2,9,16,23-四联苯基金属(Fe,Co,Ni,Cu和Zn)酞菁。研究了合成产物的质谱、溶解性、紫外光谱以及荧光光谱．结果表明,取代基使金属酞菁的溶解性增加,不发生二聚,紫外光谱发生红移。     

C-甲基取代的1-二茂铁酰氧基杂氮硅三环化合物的合成、表征及FcCOOSi(OCHCH3CH2)(OCH2CH2)2N的晶体结构

报道11个新的C-甲基取代的1-二茂铁酰氧基杂氮硅三环化合物.