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11.
Amir Mahgoub Awadelkareem Eyad Al-Shammari Abd Elmoneim O. Elkhalifa Mohd Adnan Arif Jamal Siddiqui Mejdi Snoussi Mohammad Idreesh Khan Z R Azaz Ahmad Azad Mitesh Patel Syed Amir Ashraf 《Molecules (Basel, Switzerland)》2022,27(4)
Eruca sativa Mill. (E. sativa) leaves recently grabbed the attention of scientific communities around the world due to its potent bioactivity. Therefore, the present study investigates the metabolite profiling of the ethanolic crude extract of E. sativa leaves using high resolution-liquid chromatography-mass spectrometry (HR-LC/MS), including antibacterial, antioxidant and anticancer potential against human colorectal carcinoma cell lines. In addition, computer-aided analysis was performed for determining the pharmacokinetic properties and toxicity prediction of the identified compounds. Our results show that E. sativa contains several bioactive compounds, such as vitamins, fatty acids, alkaloids, flavonoids, terpenoids and phenols. Furthermore, the antibacterial assay of E. sativa extract showed inhibitory effects of the tested pathogenic bacterial strains. Moreover, the antioxidant activity of 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydrogen peroxide (H2O2) were found to be IC50 = 66.16 μg/mL and 76.05 μg/mL, respectively. E. sativa also showed promising anticancer activity against both the colorectal cancer cells HCT-116 (IC50 = 64.91 μg/mL) and Caco-2 (IC50 = 83.98 μg/mL) in a dose/time dependent manner. The phytoconstituents identified showed promising pharmacokinetics properties, representing a valuable source for drug or nutraceutical development. These investigations will lead to the further exploration as well as development of E. sativa-based nutraceutical products. 相似文献
12.
J. O’Hara A. K. Azad A. J. Taylor 《The European Physical Journal D - Atomic, Molecular, Optical and Plasma Physics》2010,58(2):243-247
Metamaterials’ properties may be quantified through the assignment of bulk material parameters such as magnetic permeability
and electric permittivity. These assignments rely on the assumption that metamaterials are effective media, in this context
meaning that their electromagnetic properties are independent of the sample size. This assumption is not always valid, particularly
for metafilms, the surface equivalents of metamaterials. However, metamaterials comprised of numerous metafilm and dielectric
layers can be uniquely characterized in the effective medium approximation when all aspects of the metamaterial are properly
integrated. We present a simple model based on stratified systems to illustrate this fact. The model further assists in the
interpretation of novel metamaterial behaviors and offers a rapid and accurate method to determine the functionality of bulk
metamaterial-based devices. 相似文献
13.
Shen M Li G Lu BZ Hossain A Roschangar F Farina V Senanayake CH 《Organic letters》2004,6(22):4129-4132
[reaction: see text] The first practical and economical process for synthesis of 2,3-disubstituted indole compounds has been developed with high regioselectivity by palladium-catalyzed indolization of 2-bromo- or chloroanilines and their derivatives with internal alkynes. 相似文献
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16.
Frank Roschangar Jianxiu Liu Marine Dufour Vittorio Farina Azad Hossain Heewon Lee Richard Varsolona Pierre Beaulieu Chris H. Senanayake 《Tetrahedron letters》2008,49(2):363-366
A regioselective Larock approach to 3-substituted-2-pyridin-2-ylindoles from 2-alkynylpyridines and 2-iodoanilines is described herein. The unexpectedly high regioselectivity can be rationalized by a combination of steric, coordinative and electronic effects. 相似文献
17.
Hassan Azad 《Bulletin des Sciences Mathématiques》2009,133(4):330-334
Let KC be the complexification of a compact connected Lie group K. Fixing a K-invariant inner product on Lie(K), the total space of T∗K is identified with KC. We show that the Liouville symplectic form on T∗K is Kähler with respect to the complex structure of KC. 相似文献
18.
We experimentally investigate the gain saturation effect of a piece of 8 m long Erbium doped fiber (EDF), we introduce a theoretical model for the EDF ring loop, and our simulation results show very good cross-gain modulation (XGM) and wavelength conversion. We also experimentally investigate the XGM in an EDF ring loop system. Based on the study of the XGM in the EDF ring loop system, a wavelength conversion is designed with the EDF ring loop system. The EDF ring loop systems as a wavelength conversion is experimentally demonstrated by converting a sinusoidal modulated optical signal at wavelength of 1551 nm to an optical signal at wavelength of 1553.3 nm. 相似文献
19.
This presented study is to make comparison of cross sections to produce 117Sb and 90Nb via different reactions with particle incident energy up to 70 MeV as a part of systematic studies on particle-induced activations on enriched Sn, Y2O3 and ZrO2 targets, theoretical calculation of production yield, calculation of required thickness of target and suggestion of optimum reaction to produce Antimony-117 and Niobium-90. 相似文献
20.
In 1961, Brans and Dicke [1] provided an interesting alternative to general relativity based on Mach’s principle. To understand
the reasons leading to their field equations, we first consider homogeneous and isotropic cosmological models in the Brans-Dicke
theory. Accordingly we start with the Robertson-Walker line element and the energy tensor of a perfect fluid. The scalar field
φ is now a function of the cosmic time only.
Then we consider spatially homogeneous and anisotropic Bianchi type-I-cosmological solutions of modified Brans-Dicke theory
containing barotropic fluid. These have been obtained by imposing a condition on the cosmological parameter Λ(φ). Again we
try to focus the meaning of this cosmological term and to relate it to the time coordinate which gives us a collapse singularity
or the initial singularity. On the other hand, our solution is a generalization of the solution found by Singh and Singh [2].
As far as we are aware, such solution has not been given earlier. 相似文献