Azaspirene: a novel angiogenesis inhibitor containing a 1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione skeleton produced by the fungus Neosartorya sp

[structure: see text] Azaspirene isolated from the fungus Neosartorya sp. is a novel angiogenesis inhibitor with a 1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione skeleton. Azaspirene inhibits the endothelial migration induced by vascular endothelial growth factor (ED100 = 27.1 microM).     

Structure and Electrical Transport Property of a Silicopnictide ZrCuSiP

A silicopnictide ZrCuSiP was prepared through the reaction between ZrCuSi alloy and red phosphor in evacuated quartz ampoules. Rietveld analysis of the powder X-ray diffraction pattern revealed that ZrCuSiP has the ZrCuSiAs-type structure (P4/nmm) with the lattice constants of a=0.35671(1) nm and c=00.94460(4) nm. Electrical resistivity measurements at temperatures from 5 to 300 K indicated that ZrCuSiP is a metallic compound.     

Disuse atrophy alterations in normal and low temperature environments during hindlimb unloading in Syrian hamsters

This study examined whether a hypothermic environment reduces experimentally-induced atrophy of skeletal muscle, as judged by histochemical findings. The hind limbs of hamsters in a hypothermic group were suspended and flexed into plantar positions at the ankle joint, and housed for one week at 8 to 12 degree celsius in a temperature-controlled room, while the normothermic group was housed at 23 to 25 degree celsius. Hypothermia did not significantly alter the average caloric intake, and the animals from the hypothermic group lost a significant amount of body weight when compared with the normothermic group. The hypothermic group retained more muscle wet-weight and myofibers cross-sectional area in the soleus and gastrocnemius muscles compared with the normothermic group. Our results indicate that a hypothermic environment inhibits short-term muscle atrophy. This inhibition may be caused by the increased caloric intake combined with a state similar to hibernation in low-temperature environments.     

A new organic superconductor, (DODHT)2BF4 x H2O

In addition to two organic superconductors (DODHT)2X [DODHT = (1,4-dioxane-2,3-diyldithio)dihydrotetrathiafulvalene; X = PF6 and AsF6] previously reported by us, the BF4 salt of DODHT containing one water molecule [(DODHT)2BF4 x H2O] has been found to undergo a superconducting transition at 3.2 K under a hydrostatic pressure of 15.5 kbar.     

Hybridized nature of pseudogap in Kondo insulators CeRhSb and CeRhAs

We studied the electronic structure of Kondo insulators CeRhSb and CeRhAs using high-resolution photoemission spectroscopy. We found that the 4f-derived density of states shows a depletion (pseudogap) at E(F) in contrast to metallic Kondo materials. It was found that the size of the f pseudogap is smaller than that of conduction electrons ( c pseudogap) while both scale well with the Kondo temperature. The present results indicate that the hybridization between 4f and conduction electrons near E(F) is essential for the Kondo gap in the Ce-based compounds.     

Kationische Polymerisation von Phenylbutadienen. 3. Mitt. Kationische Polymerisation von 2-Phenyl-1,3-butadien

Ohne Zusammenfassung     

Stepwise and selective dealkylation of phosphotriesters with phenylthiotrimethylsilane

Phosphotriesters were dealkylated in a stepwise manner and selectively with PhSSiMe₃ in the presence of PhS^? catalyst, and ease of alkyl cleavage was found to be in accord with SN-2 reactivity order of alkyl groups. Other factors affecting the reaction were also described.     

Ultrasonic effects on electroorganic processes. Part 25. Stereoselectivity control in cathodic debromination of stilbenedibromides

Ultrasonic effects on the cathodic debromination of stilbenedibromides on a platinum cathode was examined. Current efficiency and stereoselectivity for trans-stilbene, which was formed along with cis-stilbene in the cathodic debromination of stilbenedibromides, were significantly increased under ultrasonication with an intensity over the ultrasonic cavitation threshold. This ultrasonic effect is rationalized as due to mass transport promotion in the electrode-electrolytic solution interface. A mechanism for the ultrasonic effect is discussed in detail on the basis of the reaction pathway of the debromination of stilbenedibromides.