Selective adsorption of metoprolol enantiomers using 2‐hydroxypropyl‐β‐cyclodextrin cross‐linked multiwalled carbon nanotube

This study investigates the ability of functionalized multiwalled carbon nanotubes (MWCNTs) for enantio‐separation of metoprolol chiral forms. 2Hydroxypropyl‐β‐cyclodextrin (2HP‐β‐CD) was applied as a chiral selector to functionalize carbon nanotubes (CNTs). The modified multiwalled CNT samples were characterized using scanning electron microscopy and Fourier transform infrared spectroscopy. The results of analyses showed that CNTs were successfully cross‐linked with 2HP‐β‐CD. To evaluate the enantio‐separation property of the products, the separation of metoprolol chiral forms on the initial and final products was examined. Further, UV–visible spectroscopy and polarimeter analyses were used for characterization. The results indicate that MWCNT does not have any intrinsic enantio‐separation ability, although its selectivity for enantio‐separation can be enhanced by cross‐linking it to 2HP‐β‐CD. Moreover, the optimal mass of adsorbent as well as optimal mass of functional groups is estimated to achieve maximum enantio‐separation efficiency. The results indicate that applying large amounts of 2HP‐β‐CD to CNTs functionalization decreases the cross‐linking efficiency, which consequently reduces enantio‐separation efficiency. Copyright © 2014 John Wiley & Sons, Ltd.     

A biocompatible composite based on poly(ε‐caprolactone fumarate) and hydroxyapatite

Fabrication of biodegradable composites applicable as hard tissue substitutes consisting of poly(ε‐caprolactone fumarate) (PCLF), methacrylic acid (MAA), and hydroxyapatite (HA) was investigated. PCLF macromers were synthesized by reaction of PCL diol with fumaryl chloride in the presence of propylene oxide and characterized by gel permeation chromatography, FTIR, and ¹H NMR spectroscopy. Composites were fabricated by incorporating HA as inorganic filler in PCLF matrix which followed by thermal curing of the composition using benzoyl peroxide and MAA as a free radical initiator and reactive diluent, respectively. Uniform distribution of the fine ceramic phase in the polymer matrix was elucidated by scanning electron microscopy. The effects of the initial macromer molecular weight and the filler volume fraction on mechanical properties and cytotoxicity of the composites were also examined. Significant enhancement in the mechanical properties was observed upon increasing HA content and/or initial PCLF molecular weight. The biocompatibility of the specimens was also improved with increasing ceramic phase. Copyright © 2010 John Wiley & Sons, Ltd.     

Comments on ‘‘Dynamic crack propagation in piezoelectric materials—Part I. Electrode solution’’ by Shaofan Li, Peter A. Mataga [J. Mech. Phys. Solids 44 (1996) 1799-1830]

In this comment, it is pointed out that the paper [Li and Mataga, 1996. J. Mech. Phys. Solids 44, 1799-1830], which presents original and valid solution strategy for an important problem of dynamic crack propagation in piezoelectric materials, contains ultimate quantitatively and qualitatively incorrect expressions, conclusions and plots due calculation errors. The correct calculations and corresponding correct conclusions and plots are presented.     

Nonlinear Polarization Rotation-Based Mode-Locked Erbium-Doped Fiber Laser with Three Switchable Operation States

A simple mode-locked erbium-doped fiber laser （EDFL） with three switchable operation states is proposed and demonstrated based on nonlinear polarization rotation. The EDFL generates a stable square pulse at a third harmonic pulse repetition rate of 87kHz as the 1480 nm pump power increases from the threshold of 17.5 m W to 34.3mW. The square pulse duration increases from 105 ns to 245ns as the pump power increases within this region. The pulse operation switches to the second operation state as the pump power is varied from 48.2mW to l16.Tm W. The laser operates at a fundamental repetition rate of 29 kHz with a fixed pulse width of 8.5 μs within the pump power region. At a pump power of ll6.TmW, the average output power is 3.84mW, which corresponds to the pulse energy of 131.5 ng. When the pump power continues to increase, the pulse train experiences unstable oscillation before it reaches the third stable operation state within a pump power region of 138.9 m W to 145.0 m W. Within this region, the EDFL produces a fixed pulse width of 2.8 μs and a harmonic pulse repetition rate of 58 kHz.     

EP modular operators and their products

We study first EP modular operators on Hilbert C^?-modules and then we provide necessary and sufficient conditions for the product of two EP modular operators to be EP. These enable us to extend some results of Koliha (2000) [13] for an arbitrary C^?-algebra and the C^?-algebras of compact operators.     

One‐Pot Sequential Organocatalysis: Highly Stereoselective Synthesis of Trisubstituted Cyclohexanols

A highly diastereoselective (d.r. >99:1) and enantioselective (ee value up to 96 %) synthesis of trisubstituted cyclohexanols was achieved by using a one‐pot sequential organocatalysis that involved a quinidine thiourea‐catalyzed tandem Henry–Michael reaction between nitromethane and 7‐oxo‐hept‐5‐en‐1‐als followed by a tetramethyl guanidine (TMG)‐catalyzed tandem retro‐Henry–Henry reaction on the reaction products of the tandem Henry–Michael reaction. Through a mechanistic study, it has also been demonstrated that similar results may also be achieved with this one‐pot sequential organocatalysis by using the racemic Henry product as the substrate.     

A new approach to maturity of molecules by rationality of finite groups

These two concepts, maturity in chemistry and rationality in group theory were discovered by a chemist, Fujita. In the present study, we introduce a new approach to maturity and immaturity of simple groups, using the deep theorem (Feit and Seitz in Ill J Math 33:101–131, 1988). Additionally, we prove that 1,3,5-trimethyl-2,4,6-trinitrobenzene are always unmatured and tetra platinum(II) with point group $D_{2n}$ , dihedral group of order $2n$ , is unmatured if $n\ne 1,2,3,4,6$ . Also, we compute integer-valued characters of the simple sporadic group $Ly$ .     

An examination of the role of price insurance products in stimulating investment in agriculture supply chains for sustained productivity

This study examines how managing risk by introducing commodity price insurances may improve the likelihood of increased investment in agri-food supply chains. A model is introduced which shows how insurance products on index prices can reduce the uncertainty of the impact of investment, and also how lower investment can generate the same impact as a higher investment. To show our results, we use two different frameworks which include total profit (Pareto optimal) and Stackelberg game setups. The results demonstrate that in both frameworks the investment will have a greater impact when an insurance product is present. By implication, the study presents an encouraging message to the insurance industry to introduce products to secure supply chain actors’ revenue leading to an increase in investment rate. Consequently, the study offers insight into how the role of traditional government subsidies for protecting farmers, particularly the small to medium-sized farms, may be revisited by replacing some of the existing subsidisation policies with revenue insurance.