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91.
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Andre S. Barci V. Barneoud D. Beraud R. Charvet A. Samman H. El Genevey J. Gizon A. Gizon J. Kossakowski R. Tréherne J. Weiss B. 《Zeitschrift für Physik A Hadrons and Nuclei》1982,308(2):181-182
Preliminary results on residual nuclei production in 30 MeV/A12C interaction with medium heavy targets are presented. Gamma-ray spectroscopic techniques were used. Evidence for charge and angular momentum transfer is found.
相似文献95.
96.
Andre Rosowsky Katherine K. N. Chen Nickolas Papathanasopoulos 《Journal of heterocyclic chemistry》1976,13(4):727-732
Analogs of methotrexate diethyl ester ( 1 ) were prepared, in which the distances separating the ester functions from each other and from the carboxamide function of the p-aminobenzoate moiety were varied via the use of methylene groups as “spacers”. The diethyl esters 3 and 4 , with D,L-α-aminoadipate and D,L-α-aminopimelate side chains in place of L-glutamate, displayed approximately the same order of activity as compound 1 against bacterial and mammalian cells in culture, and were inhibitors of the enzyme dihydrofolate reductase. When given intraperitoneally to L1210 1eukemic mice at a dose of 120 mg./kg. q3d 1,4,7, compound 4 produced a 67% increase in survival and no evidence of toxicity, whereas methotrexate diethyl ester ( 1 ) gave a 44% increase in survival at a dose of 45 mg./kg. q3d 1,4,7 but was toxic at higher doses. The positional isomer 2 was inactive. 相似文献
97.
98.
We present a novel means of transporting molecules in solution by applying a zero-time-average alternating motive force to the molecules, and perturbing the molecular drag coefficient synchronously with the applied force, thus causing a net drift in a direction determined by the phase of the alternating drag perturbation relative to the alternating force. We apply an electrophoretic form of the method to transport and concentrate DNA in a gel, such that all molecules migrate on average away from the nearest electrode and toward a central region. Since an electrode does not occupy this central region, this method presents the possibility of transporting and focusing DNA and other charged molecules in regions free from electrodes and the associated electrochemistry. 相似文献
99.
100.
Andre Rosowsky Marilyn K. Nadel Edward J. Modest 《Journal of heterocyclic chemistry》1972,9(3):645-650
A modified three-component reaction of arylamines, cyanoguanidine, and acetone is described, wherein formation of anomalous guanidinoquinazoline byproducts is greatly enhanced at the expense of the normal dihydro-s-triazines. Four new guanidinoquinazolines and four new dihydro-s-triazines were synthesized via this modification, starting from 2,4-, 2,5-, 3,4-, and 3,5-dimethoxyaniline. The guanidinoquinazoline to dihydro-s-triazine ratio was much higher with 3,4- and 3,5-dimethoxyaniline than with 2,4-dimethoxyaniline. 2,5-Dimethoxyaniline gave an unexpectedly low yield of guanidinoquinazoline, apparently because of steric hindrance. The modified three-component synthesis was also examined in detail with 2-naphthylamine. 相似文献