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排序方式: 共有182条查询结果,搜索用时 717 毫秒
41.
Imene Terrab Rachida Ouargli Bouhadjar Boukoussa Kamel Ghomari Rachida Hamacha René Roy Abdelkrim Azzouz Abdelkader Bengueddach 《Research on Chemical Intermediates》2017,43(7):3775-3786
Three mesoporous silica, SBA-16, SBA-15 and MCM-41, with different structures and porosities were synthesized via a hydrothermal method and their interactions with carbon dioxide (CO2) were investigated through thermal programmed desorption (TPD) and differential scanning calorimetry. TPD measurements provided precise assessments of the intrinsic affinity towards CO2, without the influence of moisture. All silica materials were found to exhibit intrinsic affinity towards carbon dioxide, but the surface basicity, expressed in terms of retained CO2 amount, is markedly influenced by increases in pore size and framework structures. SBA-15 displayed the highest CRC values, explained in terms of larger pore size, lower numbers of acidic out-of plane Si–OH and higher numbers of much less acidic in-plane silanols. These findings provide valuable information for a better understanding of the role of the silica structure in the intrinsic basicity, prior to further modifications for improving the affinity towards CO2 or merely for catalysis purposes involving CO2 as reagents, intermediates or products. 相似文献
42.
Salima Bellatreche Abdelkrim Hasnaoui Bouhadjar Boukoussa Jaime García-Aguilar Ángel Berenguer-Murcia Diego Cazorla-Amoros Abdelkader Bengueddach 《Research on Chemical Intermediates》2016,42(12):8039-8053
This paper focuses on the synthesis of nanocomposite materials, TiO2/SAPO-34, using the sol–gel method, which involves preparing a mixture between as-synthesized or calcined SAPO-34 zeolite and TiO2 gel under hydrothermal crystallization and then calcining it at 400 °C for the formation of the TiO2 anatase phase. The structural and textural features of the obtained materials were determined by various physico-chemical techniques such as thermogravimetric analysis, X-ray diffraction, scanning electronic microscopy, nitrogen sorption at 77 K, energy dispersive X-ray analysis and ultraviolet–visible spectrometry. The DRX results showed that calcination at 400 °C of the mixture between the calcined SAPO-34 and TiO2 gel led to the collapse of the original framework of zeolite, but formed the anatase TiO2 in a nano-spherical morphology; however, the use of as-synthesized SAPO-34 supports provides a mixture phase between SAPO-34 and TiO2 anatase after calcination. The photocatalytic properties of the SAPO-34/TiO2 and TiO2-type materials were tested for the removal of methylene blue (MB) dye. The MB degradation proved to increase as a function of contact time, catalyst mass and the initial concentration of MB. 相似文献
43.
Yosser Zina Abdelkrim Emna Harigua-Souiai Imen Bassoumi-Jamoussi Mourad Barhoumi Josette Banroques Khadija Essafi-Benkhadir Michael Nilges Arnaud Blondel N. Kyle Tanner Ikram Guizani 《Molecules (Basel, Switzerland)》2022,27(18)
Previous investigations of the Leishmania infantum eIF4A-like protein (LieIF4A) as a potential drug target delivered cholestanol derivatives inhibitors. Here, we investigated the mode of action of cholesterol derivatives as a novel scaffold structure of LieIF4A inhibitors on the RNA-dependent ATPase activity of LieIF4A and its mammalian ortholog (eIF4AI). We compared their biochemical effects on RNA-dependent ATPase activities of both proteins and investigated if rocaglamide, a known inhibitor of eIF4A, could affect LieIF4A as well. Kinetic measurements were conducted at different concentrations of ATP, of the compound and in the presence of saturating whole yeast RNA concentrations. Kinetic analyses showed different ATP binding affinities for the two enzymes as well as different sensitivities to 7-α-aminocholesterol and rocaglamide. The 7-α-aminocholesterol inhibited LieIF4A with a higher binding affinity relative to cholestanol analogs. Cholesterol, another tested sterol, had no effect on the ATPase activity of LieIF4A or eIF4AI. The 7-α-aminocholesterol demonstrated an anti-Leishmania activity on L. infantum promastigotes. Additionally, docking simulations explained the importance of the double bond between C5 and C6 in 7-α-aminocholesterol and the amino group in the C7 position. In conclusion, Leishmania and mammalian eIF4A proteins appeared to interact differently with effectors, thus making LieIF4A a potential drug against leishmaniases. 相似文献
44.
Naima Benchikha Imane Chelalba Hanane Debbeche Mohammed Messaoudi Samir Begaa Imane Larkem Djilani Ghamem Amara Abdelkrim Rebiai Jesus Simal-Gandara Barbara Sawicka Maria Atanassova Fadia S. Youssef 《Molecules (Basel, Switzerland)》2022,27(12)
Lobularia libyca (L. libyca) is a traditional plant that is popular for its richness in phenolic compounds and flavonoids. The aim of this study was to comprehensively investigate the phytochemical profile by liquid chromatography, electrospray ionization and tandem mass spectrometry (LC-ESI-MS), the mineral contents and the biological properties of L. libyca methanol extract. L. libyca contains significant amounts of phenolic compounds and flavonoids. Thirteen compounds classified as flavonoids were identified. L. libyca is rich in nutrients such as Na, Fe and Ca. Moreover, the methanol extract of L. libyca showed significant antioxidant activity without cytotoxic activity on HCT116 cells (human colon cancer cell line) and HepG2 cells (human hepatoma), showing an inhibition zone of 13 mm in diameter. In silico studies showed that decanoic acid ethyl ester exhibited the best fit in β-lactamase and DNA gyrase active sites; meanwhile, oleic acid showed the best fit in reductase binding sites. Thus, it can be concluded that L. libyca can serve as a beneficial nutraceutical agent, owing to its significant antioxidant and antibacterial potential and due to its richness in iron, calcium and potassium, which are essential for maintaining a healthy lifestyle. 相似文献
45.
Benoît Talbot Nicolas Mazellier Bruno Renou Luminita Danaila Mourad Abdelkrim Boukhalfa 《Experiments in fluids》2009,47(4-5):769-787
This paper addresses the ability to reliably measure the fluctuating velocity field in variable-viscosity flows (herein, a propane–air mixture), using hot-wire anemometry. Because the latter is sensitive to both velocity and concentration fluctuations, the instantaneous concentration field also needs to be inferred experimentally. To overcome this difficulty, we show that the hot-wire response becomes insensitive to the concentration of the field, when a small amount of neon is added to the air. In this way, velocity measurements can be made independently of the concentration field. Although not necessary to velocity measurements, Rayleigh light-scattering technique is also used to infer the local (fluctuating) concentration, and, therefore, the viscosity of the fluid. Velocity and concentration measurements are performed in a turbulent propane jet discharging into an air–neon co-flow, for which the density and viscosity ratios are 1.52 and 1/5.5, respectively. The Reynolds number (based on injection diameter and velocity) is 15400. These measurements are first validated: the axial decay of the mean velocity and concentration, as well as the lateral mean and RMS profiles of velocity and concentration, is in full agreement with the existing literature. The variable-viscosity flow along the axis of the round jet is then characterized and compared with a turbulent air jet discharging into still air, for which the Reynolds number (based on injection diameter and velocity) is 5400. Both flows have the same initial jet momentum. As mixing with the viscous co-flow is enhanced with increasing downstream position, the viscosity of the fluid increases rapidly for the case of the propane jet. In comparison with the air jet, the propane jet exhibits: (1) a lower local Reynolds number based on the Taylor microscale (by a factor of four); (2) a reduced range of scales present in the flow; (3) the isotropic form of the mean energy dissipation rate is first more enhanced and then drastically diminishes and (4) a progressively increasing local Schmidt number (from 1.36 to 7.5) for increasing downstream positions. Therefore, the scalar spectra exhibit an increasingly prominent Batchelor regime with a ~ k ?1 scaling law. The experimental technique developed herein provides a reliable method for the study of variable-viscosity flows. 相似文献
46.
Sciannamea V Debuigne A Piette Y Jerome R Detrembleur C 《Chemical communications (Cambridge, England)》2006,(40):4180-4182
Cobalt complexes supported on silica and Merrifield resin are effective mediators for the controlled radical polymerization of vinyl acetate. 相似文献
47.
Smaail Radi Abderrahmane Yahyi Abdelkrim Ramdani Ismail Zidane Brahim Hacht 《Tetrahedron》2006,62(39):9153-9155
The synthesis of a new tetrapyrazolic macrocyclic structure with a functionalised arm is described. The complexing properties of this new compound towards alkali metal ions (K+, Na+, Li+) were studied by liquid-liquid extraction and liquid membrane transport processes. The extracted and the transport cation percentage were determined by atomic absorption measurements and UV spectroscopy. 相似文献
48.
Urolithiasis can lead to the loss of renal function in some cases. In this study, we tested the inhibiting effect of wheat bran (Triticum aestivum L) extract on calcium oxalate crystallization in a turbidimetric model, by FTIR spectroscopy, and polarized microscopy. The results show that this plant extract has a major inhibitory effect on calcium oxalate crystallization. 相似文献
49.
Martine Assié Abdelkrim Meddour Jean-Claude Fiaud Jean-Yves Legros 《Tetrahedron: Asymmetry》2010,21(13-14):1701-1708
Alkylation of racemic 1-(6-methoxynaphth-2-yl)ethyl acetate by potassium dimethyl malonate catalyzed by a chiral palladium-DUPHOS complex afforded the substitution product with 87% ee, along with 6-methoxy-2-vinylnaphthalene that arose from an elimination process, in a 43/57 substitution/elimination ratio. The reaction performed on a mixture of quasi-enantiomeric substrates provided insight into the stereochemical course of the reaction, establishing that—for a given enantiomer of the catalyst, one enantiomer of the substrate afforded mainly the substitution product whereas the other enantiomer underwent elimination. 相似文献
50.
Hanieh Kargarzadeh Ishak Ahmad Ibrahim Abdullah Alain Dufresne Siti Yasmine Zainudin Rasha M. Sheltami 《Cellulose (London, England)》2012,19(3):855-866
Cellulose nanocrystals (CNC) were first isolated from kenaf bast fibers and then characterized. The raw fibers were subjected
to alkali treatment and bleaching treatment and subsequent hydrolysis with sulfuric acid. The influence of the reaction time
on the morphology, crystallinity, and thermal stability of CNC was investigated. Fourier transform infrared spectroscopy showed
that lignin and hemicellulose were almost entirely removed during the alkali and bleaching treatments. The morphology and
dimensions of the fibers and acid-released CNC were characterized by field emission scanning electron microscopy and transmission
electron microscopy. X-Ray diffraction analysis revealed that the crystallinity first increases upon hydrolysis and then decreases
after long durations of hydrolysis. The optimal extraction time was found to be around 40 min during hydrolysis at 45 °C with
65% sulfuric acid. The thermal stability was found to decrease as the hydrolysis time increased. The electrophoretic mobility
of the CNC suspensions was measured using the zeta potential, and it ranged from −8.7 to −95.3 mV. 相似文献