Characterization of the polymorph changes in Trimethoprim

Journal of Thermal Analysis and Calorimetry - Polymorphic transformation in Trimethoprim (TMP) drug has been studied employing differential scanning calorimetry (DSC), TG/DSC, X-ray diffraction and...     

Surface modification of calcium fluoro and hydroxyapatite by 1-octylphosphonic dichloride

The reactivity of the surface of calcium hydroxyapatite (CaHAp) and fluorapatite (CaFAp) was tested and compared by grafting the 1-octylphosphonic dichloride (C₈H₁₇OPCl₂) using a molar ratio x = 2 or 4, x = n(organic)/n(apatite). Successful synthesis was confirmed by different characterisation techniques such as X-ray powder diffraction patterns, IR spectroscopy, MAS-NMR (¹H and ³¹P) and chemical analysis.The difference between their specific surface area (SSA: 57.46 for HAp and 12.09 m²/g for FAp), the percentage of carbon measured after treatment with (C₈H₁₇OPCl₂) and the intensities of IR bands attributed to the grafted moiety suggests that the surface of hydroxyapatite is more reactive than that of fluorapatite.The ³¹P CP-MAS-NMR spectra of treated fluorapatite show a significant change in isotropic signal due to the protonation and deprotonation of superficial phosphate group. This can be explained by the difference in the nature of inorganic material.     

Antitumor,cytotoxic, and antioxidant evaluation of six heterocyclic compounds containing different heterocycle moieties

Heterocyclic compounds with different heterocycle moieties, namely benzoxazinone, benzimidazole, quinazolinone, and benzofuranone heterocyclic rings, were synthesized, characterized, and evaluated for their anticancer activity against human hepatocellular carcinoma cell line (HepG2) using sulforhodamine B (SRB) and dimethylthiazol-diphenyltetrazolium bromide (MTT) assays. Also, their cytotoxic activities were tested against human epithelioid carcinoma (Hela) cell line in comparison with normal cell, amniotic epithelial (WISH) cell line, as an in vitro toxicity estimation model. The results showed clearly that 2-(2-benzyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide 4 is the most potent antioxidant and anticancer agents. Although, 3-amino-2-benzylquinazolin-4(3H)-one 5 is less potent anticancer agent against Hela but it is more safe against normal cell (WISH).     

Stability results for the approximation of weakly coupled wave equations

In this Note, we consider the approximation of two coupled wave equations with internal damping. Our goal is to damp the spurious high frequency modes by introducing numerical viscosity terms in the approximation scheme. With these viscosity terms, we show the exponential or polynomial decay of the discrete scheme when the continuous problem has such a decay (since the spectrum of the spatial operator associated with the undamped system satisfies the generalized gap condition).     

Block based embedding of encrypted watermarks using singular value decomposition

Watermarking is a solution to the problem of copyright protection of multimedia documents over the Internet. This paper presents a block based watermarking scheme using the singular value decomposition (SVD) algorithm to embed encrypted watermarks into digital images. The paper compares between the traditional method of Liu and the proposed method for embedding encrypted watermarks. Also, a permutation based encryption algorithm and a diffusion based encryption algorithm are compared as the watermark encryption algorithms. Experimental results show that the proposed method is superior to the traditional method of Liu for embedding encrypted watermarks and extracting them efficiently under attacks. Results also show that it is preferred to use permutation based encryption algorithms than diffusion based encryption algorithms for watermark encryption due to their lower sensitivity to attacks.     

Search for dilepton resonances in pp collisions at √s=7 TeV with the ATLAS detector

This Letter reports on a search for narrow high-mass resonances decaying into dilepton final states. The data were recorded by the ATLAS experiment in pp collisions at √s=7 TeV at the Large Hadron Collider and correspond to a total integrated luminosity of 1.08 (1.21) fb(-1) in the e(+)e(-) (μ(+)μ(-)) channel. No statistically significant excess above the standard model expectation is observed and upper limits are set at the 95% C.L. on the cross section times branching fraction of Z' resonances and Randall-Sundrum gravitons decaying into dileptons as a function of the resonance mass. A lower mass limit of 1.83 TeV on the sequential standard model Z' boson is set. A Randall-Sundrum graviton with coupling k/M(Pl)=0.1 is excluded at 95% C.L. for masses below 1.63 TeV.     

Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV

Azimuthal decorrelations between the two central jets with the largest transverse momenta are sensitive to the dynamics of events with multiple jets. We present a measurement of the normalized differential cross section based on the full data set (∫Ldt=36 pb(-1)) acquired by the ATLAS detector during the 2010 sqrt(s)=7 TeV proton-proton run of the LHC. The measured distributions include jets with transverse momenta up to 1.3 TeV, probing perturbative QCD in a high-energy regime.     

Search for diphoton events with large missing transverse energy in 7 TeV proton-proton collisions with the ATLAS detector

A search for diphoton events with large missing transverse energy is presented. The data were collected with the ATLAS detector in proton-proton collisions at √s=7 TeV at the CERN Large Hadron Collider and correspond to an integrated luminosity of 3.1 pb?1. No excess of such events is observed above the standard model background prediction. In the context of a specific model with one universal extra dimension with compactification radius R and gravity-induced decays, values of 1/R<729 GeV are excluded at 95% C. L., providing the most sensitive limit on this model to date.     

Search for the Higgs boson in the H→WW→lνjj decay channel in pp collisions at √s=7 TeV with the ATLAS detector

A search for a Higgs boson has been performed in the H→WW→?νjj channel in 1.04 fb(-1) of pp collision data at √s=7 TeV recorded with the ATLAS detector at the Large Hadron Collider. No significant excess of events is observed over the expected background and limits on the Higgs boson production cross section are derived for a Higgs boson mass in the range 240 GeV相似文献