具有咖啡酰基和没食子酰基的β-二酮酸及喹噁啉酮类HIV整合酶抑制剂的设计合成及其对Cu2+的选择性识别

An efficient procedure for the synthesis of caffeoyl-and galloyl-containing β-diketoacid derivatives linked byarylamide was reported by,in the key step,dissolving the corresponding phenyl methyl ketone in THF/DME in thepresence of NaOMe as base and dimethyl oxalate as oxalylation reagent,and then separating the sodium ketoe-nolate ester.The resulting β-diketoacids underwent further condensation reaction with o-phenylenediamine to gen-erate quinoxalone derivatives in good yield,rather than 2-benzimidazol.The preliminary ion binding properties ofquinoxalone derivatives were also investigated.UV-Vis spectra showed that these compounds could selectively rec-ognize Cu~(2 )ion in ethanol and form a 1∶2 complex.     

Microcalorimetric Evaluation of the Effect of Kanamycin： An Analysis Based on the Median-Effect Principle

A study of the effect of drug, kanamycin, on the growth metabolism of recombinant Escherichia coli B 1 was carded out by microcalorimeter monitoring of the metabolic activity of treated cells. Power-time curves of growing recombinant Escherichia coli cell suspensions, treated with different kanamycin doses, were recorded. The extent of the effect was evaluated by changes in the slopes of the microcalorimetric curves and the kinetics of the drug action was interpreted from the time at which these changes reached their maximum values and maintained their maximum values. Experimental dose-effect relationships conform to the median-effect principle of the mass-action law： fa/（1-fa）=（D/D50）^m. A plot of y=lg[（fa）^1-1]^-1 versus x=lg D gives the slope m, D50 and R∞. The experimental results revealed that high concentration of kanamycin had an inhibitory effect on the growth of recombinant Escherichia coli B 1 in the lg phase, and had a promoting effect in the stationary period. Moreover, it was demonstrated that microcalorimetry was a reliable method for the detection of modulatory effects in biology.     

Li2O-TiO2-SiO2-P2O5和Li2O-TiO2-Al2O3-P2O5体系锂离子固体电解质的制备及性能研究

一些具有NASICON型网格结构的固体电解质具有高的电导率和好的稳定性,NASICON的意思是Na Super Ionic Conductor[1]。当NaZr2(PO4)3中P5 被Si4 部分取代时便可以得到具有NASICON结构的Na1 xZr2SixP3-xO12体系,其具有高的钠离子电导率。然而有相同结构的Li1 xZr2SixP3-xO12体系的离子电导率却很低,这是因为Li 半径太小,而NASICON三维网格结构的离子通道太大,两者不匹配而使电导率下降[2]。但当LiZr2(PO4)3中Zr4 被离子半径小些的Ti4 取代,所得LiTi2(PO4)3的通道就与Li 半径相匹配,适合于锂离子的迁移,从而使其电导率…     

Mo（W）－Co（Ni，Fe）簇合物的加氢脱硫催化活性

对线型、立方烷型和笼状３种不同构型的Ｍｏ（Ｗ）－Ｃｏ（Ｎｉ，Ｆｅ）－Ｓ（Ｏ）簇共１２种化合物进行了噻吩加氢脱硫和环己烯加氢的催化活性研究．讨论了簇合物的组成，金属原子的配比、价态与催化活性的关系．探讨了不同构型对活性的影响．     

金属氧化物电化学电容器

电化学电容器是一类利用电化学双电层或电极材料在电极表面及体相发生的氧化还原反应而存储能量的装置，具有高比能量、良好的可逆性和长循环寿命。金属氧化物电极目前主要有贵金属氧化物和过渡金属氧化物。本文简要介绍了金属氧化物电化学电容器的储能机理、特点及应用，总结了电极材料的制备及改性方法；并简要评述了电极材料的研究进展。     

CRYSTAL STRUCTURE OF Fe4S4[SC（CH3）3]4[（C4H9）4N]2

<正> Fe_4S_4[SC(CH_3)_3]_4[(C1H_9)_2,Mr=1193. 23,tetragonal,142d,a = 23. 272(2), c= 13. 080(5) A ,V=7084(3) A3,Z=4,DC=1. 12g·cm-3,UUUU(MoKa) = 10. 8cm-1,F(000) = 2568,R=0. 058 for 1005 observed reflections. The cluster anion contains a cubane-type Fe4S4 core compressed along the 4 axis which is crystallographically imposed. Compared to other salts with different cations ,the core is subject to slight structural distortions in different crystalline environments and crystallographic symmetry of the anion is related to that of the cation.     

一种新的永久周期磁铁聚焦的高功率宽带放大器

提出了一种新的高功率宽带放大器，它由速调管和自由电子脉塞组成，用永久周期磁铁聚焦。研究了这种器件的电子束聚焦、群聚和辐射。在速调管提供一阶调制系数为30%，波导管的半径1.51cm，摇摆器的磁场振幅0.16T，周期7.92cm，电子束的电压490kV，电流50A和半径0.368cm的条件下，预估这种器件的辐射波频率为11.4GHz，输出辐射功率为18MW，输出辐射带宽为44%。     

基于微机械加工工艺的声子晶体器件

声子晶体是一种周期复合人工超材料.声子晶体具有独有的声学特性-声学禁带,使其在声波控制和传输领域具有极强的应用潜力.利用微机械加工工艺制备的硅基声子晶体器件,可在微机电系统中实现高频弹性波的定向传输和控制,以及对弹性波能量的局域放大.设计了两种基于MEMS工艺的器件,分别用于实现功分器和谐振器的功能.内容覆盖了硅基声子晶体器件的背景、原理、设计、制造和表征等方面.     

用模拟退火法进行纯永磁波荡器磁块组合优化

 纯永磁波荡器由多个磁块组成,磁块的剩磁离散性会引起波荡器磁场误差,从而影响储存环工作状态和自发辐射谱质量。在波荡器磁块安装之前,使用模拟退火法对磁块进行组合排序优化,可以使峰值场强误差降低到10 ^-4量级以下,磁场一次积分降低到10^-6 T·m量级,二次积分降低到10 ^-6 T·m ²量级,优化结果不依赖于初始状态的选择。给出优化的详细过程,提出了根据磁块剩磁快速计算波荡器峰值场强误差和积分场的方法。