Synthesis,characterization, and antioxidant and anticholinesterase activities of pyrazolo derivatives

Twenty-four pyrazolo derivatives (1–4)(a-f) were synthesized and characterized by FTIR, ¹H, and ¹³C NMR (Nuclear Magnetic Resonance), and elemental analysis. The synthesized compounds were also investigated for their antioxidant and anticholinesterase activities. The compounds (3–4)(a-f) carrying morpholine ring were more active than the piperidinyl containing compounds (1–2)(a-f) in both activities. The compound 4f showed higher activity in both assays as compared with the others. Additionally, the anticholinesterase activity test provided higher values than the galantamine in the BChE assay. Therefore, compound 4f can be used as anticholinesterase agent and/or anticholinesterase assay standard.     

A heat transfer problem with exponential memory and the associated thermal stresses

In this study, a heat transfer problem defined by the Caputo–Fabrizio derivative, which is known to behave by the exponential decaying law, is addressed in an axially symmetric cylindrical region. Thus, the fundamental solutions of the heat diffusion process and the associated thermal stresses are aimed to find. For this purpose, Laplace and finite Hankel integral transforms are applied according to the geometry of the region. To obtain the thermal stresses, constitutive relations of the classical thermoelasticity theory are used. The effects of fractional orders on the diffusion process are illustrated graphically using MATLAB.     

Search for the global minimum structures of AlB3H2n (n = 0 − 6) clusters

The global minimum structures of AlB₃H_2n (n = 0–6) clusters are determined using the stochastic search method at the B3LYP/6–31G level of theory. These initially specified geometries are recalculated using B3LYP and CCSD(T) methods using the 6–311++G^** basis set. The structural and electronic properties of the two lowest‐lying isomers are presented. The structural parameters obtained for aluminum borohydride are compared with the experimental and theoretical results. The H₂ fragmentation energies of the most stable isomers are investigated. Chemical bonding analyses for the global minimum of AlB₃H_2n (n = 0–6) clusters are performed using the adaptive natural density partitioning method. © 2014 Wiley Periodicals, Inc.     

Markov–Dubins path via optimal control theory

Markov–Dubins path is the shortest planar curve joining two points with prescribed tangents, with a specified bound on its curvature. Its structure, as proved by Dubins in 1957, nearly 70 years after Markov posed the problem of finding it, is elegantly simple: a selection of at most three arcs are concatenated, each of which is either a circular arc of maximum (prescribed) curvature or a straight line. The Markov–Dubins problem and its variants have since been extensively studied in practical and theoretical settings. A reformulation of the Markov–Dubins problem as an optimal control problem was subsequently studied by various researchers using the Pontryagin maximum principle and additional techniques, to reproduce Dubins’ result. In the present paper, we study the same reformulation, and apply the maximum principle, with new insights, to derive Dubins’ result again. We prove that abnormal control solutions do exist. We characterize these solutions, which were not studied adequately in the literature previously, as a concatenation of at most two circular arcs and show that they are also solutions of the normal problem. Moreover, we prove that any feasible path of the types mentioned in Dubins’ result is a stationary solution, i.e., that it satisfies the Pontryagin maximum principle. We propose a numerical method for computing Markov–Dubins path. We illustrate the theory and the numerical approach by three qualitatively different examples.     

The complexity of the topological conjugacy problem for Toeplitz subshifts

In this paper, we analyze the Borel complexity of the topological conjugacy relation on Toeplitz subshifts. More specifically, we prove that topological conjugacy of Toeplitz subshifts with separated holes is hyperfinite. Indeed, we show that the topological conjugacy relation is hyperfinite on a larger class of Toeplitz subshifts which we call Toeplitz subshifts with growing blocks. This result provides a partial answer to a question asked by Sabok and Tsankov.