AES chemunex ADIAFOOD detection system for Listeria spp. environmental sample testing

The ADIAFOOD Detection System for the detection of Listeria species from environmental surfaces is based on real-time PCR technology and allows rapid pathogen detection within 21 h. The strength of the ADIAFOOD technology resides in its ability to rapidly and accurately detect Listeria species present on surfaces, such as stainless steel, plastic, ceramic, and sealed concrete. The technology is easy to use and versatile.     

Combinatorial chemistry in glycobiology

The application of combinatorial chemistry to glycobiology historically has proven challenging due to numerous synthetic hurdles. The advent of novel methodologies has enabled the production of natural as well as mimetic analogues for proof-of-concept experiments and SAR. This review highlights some of the recent synthetic advances in combinatorial carbohydrate synthesis. The application of carbohydrate libraries in glycobiology is also discussed.     

Prisoner's dilemma and clusters on small‐world networks

The structure of interaction plays an important role in the outcome of evolutionary games. This study investigates the evolution of stochastic strategies of the prisoner's dilemma played on structures ranging from lattices to small world networks. Strategies and payoffs are analyzed as a function of the network characteristics of the node they are playing on. Nodes with lattice‐like neighborhoods tend to perform better than the nodes modified during the rewiring process of the construction of the small‐world network. © 2007 Wiley Periodicals, Inc. Complexity 12:22–36, 2006     

Large-scale failure modes of dielectric elastomer actuators

Dielectric elastomer actuators (DEAs) show promise for robotic and mechatronic applications. However, to date, these actuators have experienced high rates of failure that have prevented their practical application. Here, large scale modes of failure of DEAs and their performance limits are studied. The objective is to provide design guidelines and bound the performance of DEAs that avoid failure. An idealized DEA is modeled and its failure is predicted as a function of film pre-stretch used during actuator fabrication, actuation voltage, and stretch rate. Three failure modes are considered: pull-in, dielectric strength, and material strength. Each failure mode is shown to dominate for different combinations of pre-stretch and stretch rate. High stretch rates lead to dielectric strength failure while low stretch rates lead to pull-in failure. Material strength failure is less important for most cases. Model predictions are validated experimentally using practical DEAs operating under load. This study suggests that DEAs cannot be operated reliably under load for long periods of time or low stretch rates due to pull-in failure limitations. To be reliable, DEAs must be used for short periods of time with high stretch rates.     

Potential-biased, asymmetric waveforms for charge-injection with activated iridium oxide (AIROF) neural stimulation electrodes

The use of potential biasing and biphasic, asymmetric current pulse waveforms to maximize the charge-injection capacity of activated iridium oxide (AIROF) microelectrodes used for neural stimulation is described. The waveforms retain overall zero net charge for the biphasic pulse, but employ an asymmetry in the current and pulse widths of each phase, with the second phase delivered at a lower current density for a longer period of time than the leading phase. This strategy minimizes polarization of the AIROF by the charge-balancing second phase and permits the use of a more positive anodic bias for cathodal-first pulsing or a more negative cathodic bias for anodal-first pulsing to maximize charge injection. Using 0.4-ms cathodal-first pulses, a maximum charge-injection capacity of 3.3 mC/cm2 was obtained with an 0.6-V bias (versus Ag/AgCl) and a pulse asymmetry of 1:8 in the cathodal and anodal pulse widths. For anodal-first pulsing, a maximum charge capacity of 9.6 mC/cm2 was obtained with an asymmetry of 1:3 at an 0.1-V bias. These measurements were made in vitro in carbonate-buffered saline using microelectrodes with a 2000 microm2 surface area.