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1.
Marsella MJ Yoon K Estassi S Tham FS Borchardt DB Bui BH Schreiner PR 《The Journal of organic chemistry》2005,70(5):1881-1884
Photochemical cyclization of compound 1, a homoenediyne (-CCC=CCH2CC-) bearing two ethynylanthracene chromophores, yields two isomeric dihydrocyclopent[a]indene ring systems, spiro-fused to the 9-position of a 9,10-dihydroanthracene moiety. Evidence of a photochemically initiated diradical cyclization pathway is proposed on the basis of (i) hydrogen abstraction from reaction with 1,4-cyclohexadiene (1,4-CHD) and (ii) the observation of 1,4-addition of benzene (solvent). The reaction was further analyzed by a complete density functional theory (DFT) study, using an unrestricted approach (UBLYP) with a 6-31G* basis set for the open-shell triplet states of the reactants, products, and diradical intermediates to model the photochemical nature of observed transformation. A mechanism detailing the observed cyclization/addition reaction is proposed. 相似文献
2.
Spectrofluorometric determination of certain quinolone antibacterials using metal chelation 总被引:1,自引:0,他引:1
Simple, rapid, reliable, and sensitive spectrofluorometric methods were developed for the determination of eight quinolone antibacterials namely ciprofloxacin, norfloxacin, lomefloxacin, difloxacin, amifloxacin, pefloxacin, ofloxacin, and nalidixic acid. The methods depend on the chelation of each of the studied drugs with zirconium, molybdenum, vanadium or tungsten to produce fluorescent chelates. Different factors affecting the relative fluorescence intensity of the resulting chelates were studied and optimised. At the optimum reaction conditions, the drug-metal chelates showed excitation maxima ranging from 274 to 295 nm and emission maxima ranging from 409 to 495 nm. The chelates were found to be stable at room temperature for 2 days and show good stability upon increasing temperature to 50 °C for about 1 h. Rectilinear calibration graphs were obtained in the range of 10-60 ng ml−1 for each of the investigated drugs and the limits of detection and quantitation ranged from 1.214 to 2.046 and from 4.047 to 6.819 ng ml−1, respectively. The molar ratios of the formed chelates were determined by Job's method and their association constants were also calculated. The developed methods were applied successfully for the determination of the studied drugs in their pharmaceutical dosage forms with a good precision and accuracy compared to official and reported methods as revealed by t- and F-tests. They were also applied for the determination of studied drugs in spiked urine and plasma samples. 相似文献
3.
Mohamed M. Shoukry Kamal Aziz Eman M. Shoukry Samia Hamdallah 《Transition Metal Chemistry》1989,14(2):115-118
Summary The formation constants of 1-phenyl-3-thiazole-2-ylthiourea complexes with some bivalent metal ions (CuII, NiII, ZnII and MnII) have been determined in 75% EtOH–H2O. Complexes of CuII, NiII, ZnII, HgII and PdII have been isolated and characterized by conductance, i.r., electronic spectra and magnetic measurements. The ligand forms ML complexes with CuII and HgII and ML2 with NiII, ZnII and PdII, where L is the uninegatively charged bidentate ligand and binds through the ring nitrogen and thiocarbonyl sulphur atoms. 相似文献
4.
Sylvain Achelle Samia Kahlal Jean-Yves Saillard Nolwenn Cabon Bertrand Caro Françoise Robin-le Guen 《Tetrahedron》2014
Thirteen novel dipolar and V-shaped chromophores with pyranylidene electron-donating part, diazine electron-withdrawing part and various π-linkers were synthesized. The extent of intramolecular charge transfer, structure-property relationships and optical properties were further investigated by UV/Vis absorption, electrochemistry, and DFT calculations. 相似文献
5.
M. H. Elnagdi M. A. Selim F. M. Abd El Latif S. Samia 《Phosphorus, sulfur, and silicon and the related elements》2013,188(5):1175-1182
5-Acetyl-2-cyanomethyl-4-methylthiazole, 2-aminothiazole, and 5-N-benzoylamino-1,3,4-thiadiazole-2-yl-acetonitrile react with acetone, and malononitrile derivatives in the presence of sulfur to yield the corresponding thiophene derivatives. Also, 4-furylmethylene-2-phenyl-2-oxazolin-5-ones react with thiophenol, and/or thionaphthol to give the thiolester derivatives in one-pot synthesis. The structures of the products were based on IR, 1 H NMR, and elemental analysis. 相似文献
6.
Nasser Sally Salama Ismail Mostafa Samia M. Elgawish Mohamed Saleh 《平面色谱法杂志一现代薄层色谱法》2018,31(6):469-476
JPC – Journal of Planar Chromatography – Modern TLC - The discovery of potent antidiabetic drugs is of necessity owing to the rapid prevalence of diabetes worldwide. The investigation... 相似文献
7.
Samia Guezane Lakoud Malika Berredjem Nour-Eddine Aouf 《Phosphorus, sulfur, and silicon and the related elements》2013,188(6):762-768
Abstract A new series of modified α-amidophosphonates (or β-ketophosphonate) was synthesized by an efficient method, starting from aminoesters and chloroacetyl chloride. We have established that chloroacetyl chloride is a suitable reagent allowing the introduction a halogen moiety for the Arbuzov reaction. The α-amidophosphonates were prepared in two steps (acetylation, phosphorylation). Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. 相似文献
8.
Dr. Subrat Kumar Barik Shou-Chih Huo Chun-Yen Wu Tzu-Hao Chiu Jian-Hong Liao Dr. Xiaoping Wang Dr. Samia Kahlal Prof. Jean-Yves Saillard Prof. C. W. Liu 《Chemistry (Weinheim an der Bergstrasse, Germany)》2020,26(46):10471-10479
Although atomically precise polyhydrido copper nanoclusters are of prime interest for a variety of applications, they have so far remained scarce. Herein, this work describes the synthesis of a dithiophosphate-protected copper(I) hydride-rich nanocluster (NC), [Cu30H18{S2P(OnPr)2}12] ( 1H ), fully characterized by various spectroscopic methods and single-crystal X-ray diffraction. The X-ray structure of 1H reveals an unprecedented central Cu12 hollow icosahedron. Six faces of this icosahedron are capped by Cu3 triangles, the whole Cu30 core being wrapped by twelve dithiophosphate ligands and the whole cluster has ideal S6 symmetry. The locations of the 18 hydrides in 1H were ascertained by a single-crystal neutron diffraction study. They are composed of three types: capping μ3-H, interstitial μ4-H (seesaw) and μ5-H ligands (square pyramidal), in good agreement with the DFT simulations. The numbers of hydrides and ligand resonances in the 1H NMR spectrum of 1H are in line with their coordination environment in the solid state, retaining the S6 symmetry in solution. Furthermore, two new Se-protected polyhydrido copper nanoclusters, [Cu30H18{Se2P(OR)2}12] ( 2H : R=iPr 3H : R=iBu) were synthesized from their sulfur relative 1H via ligand displacement reaction and their X-ray structures feature the exceptional case where both the NC shape and size are fully conserved during the course of ligand exchange. DFT and TD-DFT calculations allow understanding the bonding and optical properties of clusters 1H – 3H . In addition, the reaction of 1H with [Pd(PPh3)2Cl2] in the presence of terminal alkynes led to the formation of new bimetallic Cu−Pd alloy clusters [PdCu14H2{S2P(OnPr)2}6(C≡CR)6] ( 4 : R=Ph; 5 : R = C6H4F). 相似文献
9.
Guezane Lakoud Samia Merabet-Khelassi Mounia Aribi-Zouioueche Louisa 《Research on Chemical Intermediates》2016,42(5):4403-4415
Research on Chemical Intermediates - Nickel (II) sulfate hexahydrate is used for the first time as an efficient catalyst for the one-pot synthesis of α-aminophosphonates by three-component... 相似文献
10.