以8807号台风为例分析杭辫市台风、暴雨的特点、原因及对策

本文分析了198“年”月“日杭州遭到的号强台风暴雨(简称“807号命覃静b .、杭州市j幸尸成的灾害特点及原因,奔此总体规对,基础设施。市政建设、防基础炎抗上对杭)}I I市的胶灾抗灾提出对策声口建灾祝供科学依据,也为东南沿海异芭议,为城市的城市的防灾抗灾对策研究提供参考依据.     

Gold‐Nanoparticle‐Decorated Boron Nitride Nanosheets: Structure and Optical Properties

Synergetic cooperation of individual components of the nanocomposites (NCs) is responsible for their novel properties that lead to various technological applications. A simple chemical process depicting the deposition of functionalized gold nanoparticles on the surface of boron nitride nanosheets (BNNSs) in solution is reported. The structure, chemical composition, and optical properties of nanosheets are systematically studied. The deposition of Au nanoparticles on BNNS (BNNS_Au) results in plasmonic band modulation, thus altering the optoelectronic properties of BNNSs. The intense surface plasmon absorption band of BNNS_Au is narrowed and red‐shifted relative to the absorption band of as synthesized monometallic BNNSs. The observations reflect the strong interfacial interaction between BNNS and Au nanoparticles. This approach constitutes a basis for a simple process leading to the preparation of functionalized BNNSs and their utilization as nanoscale templates for assembly and integration with other nanoscale materials for futuristic optoelectronic devices.     

High temperature enthalpy increment and thermodynamic functions of U2Ti

This study investigated thermodynamic properties of uranium–titanium alloy to determine its suitability for storage of hydrogen isotopes. The enthalpy increments of U₂Ti were measured using a high temperature inverse drop calorimeter in the temperature range of 299–1,169 K. Temperature dependence of the molar enthalpy increment and molar heat capacity is expressed in the form $ H^\circ_{\text{m}} (T) - H^\circ_{\text{m}} (298.15\,{\text{K}})({\text{J }}\,{\text{mol}}^{ - 1} ) = 23.236(T/{\text{K}}) + 53.292 \times 10^{ - 3} (T/{\text{K}})^{2} - 21.294 \times 10^{5} ({\text{K}}/T) - 4523 $ and $ C^\circ_{\text{p,m}} ({\text{J}}\,{\text{K}}^{ - 1} \,{\text{g}}^{ - 1} ) = 23.236 + 10.6584 \times 10^{ - 2} (T/{\text{K}}) + 21.294 \times 10^{5} ({\text{K}}/T)^{2} (300 \le T/{\text{K}} \le 900) $ , respectively. A set of self consistent thermodynamic functions such as entropy, Gibbs energy function, heat capacity, and Gibbs energy and enthalpy values for U₂Ti have been computed using data obtained in this study and required data from the literature.     

Molecular Insights into the Antistress Potentials of Brazilian Green Propolis Extract and Its Constituent Artepillin C

Propolis, also known as bee-glue, is a resinous substance produced by honeybees from materials collected from plants they visit. It contains mixtures of wax and bee enzymes and is used by bees as a building material in their hives and by humans for different purposes in traditional healthcare practices. Although the composition of propolis has been shown to depend on its geographic location, climatic zone, and local flora; two largely studied types of propolis: (i) New Zealand and (ii) Brazilian green propolis have been shown to possess Caffeic Acid Phenethyl Ester (CAPE) and Artepillin C (ARC) as the main bioactive constituents, respectively. We have earlier reported that CAPE and ARC possess anticancer activities, mediated by abrogation of mortalin-p53 complex and reactivation of p53 tumor suppressor function. Like CAPE, Artepillin C (ARC) and the supercritical extract of green propolis (GPSE) showed potent anticancer activity. In this study, we recruited low doses of GPSE and ARC (that did not affect either cancer cell proliferation or migration) to investigate their antistress potential using in vitro cell based assays. We report that both GPSE and ARC have the capability to disaggregate metal- and heat-induced aggregated proteins. Metal-induced aggregation of GFP was reduced by fourfold in GPSE- as well as ARC-treated cells. Similarly, whereas heat-induced misfolding of luciferase protein showed 80% loss of activity, the cells treated with either GPSE or ARC showed 60–80% recovery. Furthermore, we demonstrate their pro-hypoxia (marked by the upregulation of HIF-1α) and neuro-differentiation (marked by differentiation morphology and upregulation of expression of GFAP, β-tubulin III, and MAP2). Both GPSE and ARC also offered significant protection against oxidative stress and, hence, may be useful in the treatment of old age-related brain pathologies.     

Effect of hydrophilic polymer on complexing efficiency of cyclodextrins towards efavirenz-characterization and thermodynamic parameters

The present work describes the effect of PVP on the complexation efficiency of cyclodextrins towards efavirenz, a poorly soluble antiretroviral agent imparting irritating sensation to buccal cavity. The phase solubility study indicates 1:1 stoichiometry for binary and ternary systems. DSC and XRPD revealed complete inclusion only in the lyophilized systems. The ternary systems were autoclaved before being lyophilized for the best results. Proton NMR suggests that the chlorobenzene part of benzoxazinone ring of the drug is involved in inclusion and was confirmed by 2D-COESY. The thermodynamic parameters, indicative of complexation efficiency were calculated calorimetrically by determining the interaction enthalpy of efavirenz with cyclodextrins in the presence and absence of PVP. The value of stability constants increased in the order β-CD?<?HP-β-CD?<?M-β-CD and is still higher in the presence of PVP illustrating the facilitation of the inclusion. Molar enthalpy of interaction of autoclaved solid formulation determined calorimetrically indicated stronger interaction for efavirenz:M-βCD-PVP system (?12.20?kJ/mol) which showed highest solubility and dissolution rate. The in vitro measurement of permeability showed a ten fold increase in the flux for the autoclaved formulation containing efavirenz-M-β-CD-PVP. In conclusion, encapsulation by cyclodextrins increases the solubility and suppresses the oral irritation of efavirenz. PVP further increases the complexation efficiency and decreases the bulk of cyclodextrins.     

Green synthesis and characterization of silver nanoparticles by Allium cepa L. to produce silver nano‐coated fabric and their antimicrobial evaluation

This research work was proposed to study the antimicrobial activity of the silver nanocoated fabric with the purpose of producing good dressing and clothing material. We synthesized simple, ecofriendly, cost‐effective and sustainable silver nanoparticles by using the aqueous extract of Allium cepa L. Here, A. cepa L. acts as a good reducing and capping agent that produced stable silver nanoparticles having particle size of range 36 ± 1 to 98 ± 2 nm, Poly dispersiblity index 0.234 ± 0.61 to 1.023 ± 0.33 and Zeta potential ‐12 ± 1.5 mV to ‐26 ± 1.2 mV. The effect of temperature and extract volume used was considered for optimization of synthetic procedure. The nanocoated fabric was characterized for morphological study, size (using transmission electron microscopy (TEM) and field emission scanning electron microscopy (FE‐SEM) and zeta‐potential (Zeta Potentiometer). The presence of functional groups were observed by using attenuated total reflection‐Fourier transform infrared (ATR‐FTIR) and Raman spectroscopy. The crystallinity and structural property of the synthesized silver nanoparticles were studied in terms of Powder X‐ray diffraction (PXRD). An IC₅₀ value and zone of inhibition was studied which demonstrate that the silver nanocoated fabric have an excellent antibacterial property against Gram‐negative (Escherichia coli) and Gram‐positive (Staphylococcus aureus) bacteria. Further nanocoated fabric material was washed (with function of time 0, 10, 25, and 50 laundry cycles) and still retained their anti‐bacterial activity towards both strain. Initially there was 52 μg/ml of silver nanoparticles on the cotton fabric but after 50 laundry cycle in 500 ml of distilled water the fabric showed 92% efficiency against gram positive and 90% efficacy toward gram negative bacteria. It was found that 4.16 μg/ml nano particles leached in case of S. Aureus and 5.2 μg/mL silver nanoparticles leached in case of E. coli. Nanocoated fabric material synthesized using green synthesis was found to be economical with good resistance to washing.