DCE-MRI参数联合IFIT1基因对腰椎间盘突出患者椎间盘退变程度的评估价值

探讨DCE-MRI参数及IFIT1基因对腰椎间盘突出症(LDH)患者椎间盘退变(IDD)程度的评估价值。随机选取确诊的66例LDH患者作为研究对象,根据改良Pfirrmann分级法将患者分为2组:轻中度IDD(Ⅰ~Ⅲ级)组(46例)和重度IDD(Ⅳ~Ⅴ级)组20例。通过DCE-MRI检查考察患者的K-trans值,采用日本骨科学会评分(JOA)评估腰椎功能,采用视觉模拟评分法(VAS)评估腰部疼痛,采用RT-PCR检测外周血单个核细胞(PBMC)中IFIT1的mRNA表达。轻中度IDD组的K-trans值显著低于重度IDD组。轻中度IDD组患者PBMC中的IFIT1 mRNA相对表达量显著低于重度IDD组。K-trans值与PBMC中的IFIT1 mRNA水平和VAS评分正相关,与JOA评分负相关(P<0.05)。PBMC中的IFIT1 mRNA水平与VAS评分正相关,与JOA评分负相关(P<0.05)。K-trans值和PBMC中的IFIT1 mRNA水平联合诊断重度IDD的AUC值、敏感性和特异性分别为0.991、91.3%和100.0%,AUC值和特异性均高于单独诊断。DCE-MRI检查中的K-trans值联合PBMC中的IFIT1 mRNA水平可用于LDH患者IDD程度的诊断。     

Three-dimensional size and orientation of the precipitates in AZ91 magnesium alloys measured by TEM techniques

Knowledge of the microscopic structure, including three-dimensional (3-D) size and orientation of the precipitates, is essential to fully understand the mechanical properties of the magnesium alloys and designing the alloys with better performance. Analytical TEM with high spatial resolution offers the simultaneous measurements of 3-D size, structure, orientation, composition of the precipitates from one typical sample along an established crystallographic axis. Besides popular Burgers orientation relationship (OR), other ORs such as Pitsch--Schrader OR, Crawley OR, Potter OR and a new OR with the form of [0001]_α 1.0° from [311]_γ and (11\bar 20)_α 2.0° from (03\bar 3)_γ between the magnesium matrix and the precipitate γ -Mg₁₇Al₁₂ are identified by TEM imaging and diffraction techniques. As a case study, the thicknesses of the individual precipitates with Burgers OR are further measured to be 100--200~nm through both electron energy-loss spectroscopy and x-ray energy dispersive spectroscopy combining differential x-ray absorption and extrapolation, which are in agreement with the overall 3-D size statistic distribution results obtained through analysing various samples along various directions. Furthermore, the fabricated wedge-shape structure provides a platform on which to study the dependence of the interfacial strain on the variation of the thickness.     

Al72Ni20Co8十次准晶的新结构模型

1984年准晶的发现刚由Shechtman等人发表,立即就有科学家借用英国数学家、物理学家Penrose研究数学上的拓扑问题时提出的拼砌图(tiling pattern)来描述其结构.它至少需要两种结构单元按照一种严格的匹配规则(matching rule)无重叠地铺满整个平面来得到完美的准周期结构.这就带来了疑问：为什么准晶的结构需要两种以上的结构单元?这种严格的匹配规则和长程序如何能在急冷凝固这种非平衡条件下得到保证?研究准周期结构生长模型的物理学家们分别从能量最小稳定和熵最大稳定的角度探讨了如何由两种以上的结构单元得到准周期的结构,并且提出随机拼砌相对于严格匹配的拼砌更稳定的观点,但这一课题仍然具有很大的争议.所有这一切说明了拼砌图在描述准晶生长及稳定性方面困难重重.     

与方波合成有关的李萨如图形的实验与理论研究

通过方波与方波、正弦波与方波合成的图形来研究李萨如图形,利用傅里叶级数理论把方波展开为正弦和余弦形式的傅里叶级数,然后利用Matlab软件来合成2列相互垂直的方波与正弦波以及2列方波的李萨如图形,并与实验上观察到的现象进行比较,并分析了两者之间的差异.     

Theoretical derivation of the crystallographic parameters of polytypes of long-period stacking ordered structures with the period of 13 and 14 in hexagonal close-packed system

Based on crystallographic theory, there are 63 kinds of polytypes of 13H long-period stacking order(LPSO) structure,126 kinds of polytypes of 14H LPSO structure, 120 kinds of polytypes of 39R LPSO structure, and 223 kinds of polytypes of 42R LPSO structure in a hexagonal close-packed(HCP) system, and their stacking sequences and space groups have been derived in detail. The result provides a theoretical explanation for the various polytypes of the LPSO structure.     

OECD学习框架2030视角下我国初中统计与概率内容分析及其启示

1引言在全球化、信息化与知识社会的背景下,各国综合国力的竞争变得越来越激烈,已经从过去表层的生产力水平竞争,转化为深层的以人才为中心的竞争[1],因此各国更加重视学校教育中的人才培养和课程建设.当前各国教育不断思考的一个核心问题就是,为了成功地融入未来社会、适应未来发展,学生需要掌握哪些知识、技能、态度与价值观,应该具备什么样的关键能力和素养.     

光照和氮素对外来植物凤眼莲生长和生理特性的影响

通过研究不同光照和氮素营养处理的外来植物凤眼莲的生长、生物量分配、硝酸还原酶活性、游离氨基酸以及可溶性蛋白质含量变化，探讨其对环境适应性的生理学机制。凤眼莲表现出极强的可塑性，随光照和氮素营养的增加，凤眼莲生长速率明显加快，氮素代谢关键酶硝酸还原酶活性上升。根部吸收的硝酸根离子大部分运输到叶片中还原，氮素同化效率高。氨基酸含量和可溶性蛋白质含量呈现明显的变化，叶片可溶性蛋白质含量与根冠生物量分配显著相关。本研究表明风眼莲对光照和氮素表现出很强的适应性，其快速生长和高可塑性依赖于对环境变化的牛理响廊。     

外来种喜旱莲子草的克隆生长特性

通过对外来种喜旱莲子草（Alternanthera philoxeroides（Mart．）Griseb）生长指标的测定和分析，研究了它的克隆生长规律，并探讨丁它的觅食行为．在一个生长季节内，喜旱莲子草生物量增加了近30倍，一级葡萄茎分株数增加了近50倍，最长的一级葡萄茎长度增长了近40倍，一级葡萄茎总长度增长了近13倍；一、二、三级葡萄茎上的总分株数增加了近130倍，3个级别匍匍苇总长度增长了近28倍．通过各级葡萄茎个数，葡萄茎总长度和葡萄茎总分株数比较发现，二级葡萄茎比一、二级葡萄苇生长的都要快，而一级葡萄茎的间隔物平均长度远远大于二级和三级葡萄茎．克隆植物的觅食行为与它的克隆生长紧密相连，从觅食行为来看，喜旱莲子草克隆构型随生长季节的变化说明了它对生长季节具有很强的适应性．这种快速克隆生长的特性和对生长季节的适应性有利于喜旱莲子成功入侵新的生境。     

Another Conserved Quantity by Mei Symmetry of Tzénoff Equation for Non-Holonomic Systems

As a direct result of Mei symmetry of the Ténoff equation for non-holonomic mechanical systems, another conserved quantity is studied. The expression and the determining equations of the above conserved quantity are also presented. Using this method, it is easier to find out conserved quantity than ever. In the last, an example is presented to illustrate applications of the new results.