Study of Heat Transport in Bénard-Darcy Convection with g-Jitter and Thermo-Mechanical Anisotropy in Variable Viscosity Liquids

The effects of temperature-dependent viscosity, gravity modulation and thermo-mechanical anisotropies on heat transport in a low-porosity medium are studied using the Ginzburg–Landau model. The effect of gravity modulation is to decrease the Nusselt number, Nu and variable viscosity leads to increase in Nu. The thermo-mechanical anisotropies have opposite effect on Nu with thermal anisotropy decreasing the heat transport.     

Thermal property of binary tetrahedral semiconductors

In this paper we present an expression relating the lattice thermal expansion coefficient α_L (10⁻⁶ K⁻¹) for the A^IIIB^V and A^IIB^VI semiconductors with the product of ionic charges (Z₁Z₂), melting temperature (T_m) and nearest neighbor distance d (Å). The lattice thermal expansion coefficient of these compounds exhibit a linear relationship when plotted on a log–log scale against the melting temperature (T_m), but fall on different straight lines according to the ionic charge product of the compounds. A good agreement has been found between the experimental and calculated values of the lattice thermal expansion coefficient for A^IIIB^V and A^IIB^VI semiconductors.     

Sensitive and Multiplexed On‐chip microRNA Profiling in Oil‐Isolated Hydrogel Chambers

Although microRNAs (miRNAs) have been shown to be excellent indicators of disease state, current profiling platforms are insufficient for clinical translation. Here, we demonstrate a versatile hydrogel‐based microfluidic approach and novel amplification scheme for entirely on‐chip, sensitive, and highly specific miRNA detection without the risk of sequence bias. A simulation‐driven approach is used to engineer the hydrogel geometry and the gel‐reaction environment is chemically optimized for robust detection performance. The assay provides 22.6 fM sensitivity over a three log range, demonstrates multiplexing across at least four targets, and requires just 10.3 ng of total RNA input in a 2 hour and 15 minutes assay.     

High-Throughput GC-FID Method for the Determination of Residual Solvents in Early-Phase Drug Discovery Samples

Chromatographia - In drug discovery environment, determination of residual solvents is indispensable and requires rapid analysis covering a maximum number of commonly used solvents especially with...     

Determination of ten rare-earth elements and yttrium in silicate rocks by ICP-AES without separation and preconcentration

Lanthanum, cerium, neodymium, samarium, europium, gadolinium, dysprosium, erbium, ytterbium, lutetium and yttrium have been determined in 8 international rock standards by inductively coupled plasma atomic emission spectrometry (ICP-AES) without prior ion-exchange separation and preconcentration. The results for La, Ce, Nd, Eu, Dy, Yb and Y were in good agreement with the reported values, whereas those for Sm, Gd, Er and Lu were less accurate. However, the results for Sm, Gd, Er and Lu can also be used for studies of petrogenesis.     

Bioactive Components of Salvia and Their Potential Antidiabetic Properties: A Review

The utilization of therapeutic plants is expanding around the globe, coupled with the tremendous expansion of alternative medicine and growing demand in health treatment. Plants are applied in pharmaceuticals to preserve and expand health—physically, mentally and as well as to treat particular health conditions and afflictions. There are more than 600 families of plants identified so far. Among the plants that are often studied for their health benefit include the genus of Salvia in the mint family, Lamiaceae. This review aims to determine the bioactive components of Salvia and their potential as antidiabetic agents. The search was conducted using three databases (PubMed, EMBASE and Scopus), and all relevant articles that are freely available in the English language were extracted within 10 years (2011–2021). Salvia spp. comprises many biologically active components that can be divided into monoterpenes, diterpenes, triterpenes, and phenolic components, but only a few of these have been studied in-depth for their health benefit claims. The most commonly studied bioactive component was salvianolic acids. Interestingly, S. miltiorrhiza is undoubtedly the most widely studied Salvia species in terms of its effectiveness as an antidiabetic agent. In conclusion, we hope that this review stimulates more studies on bioactive components from medicinal plants, not only on their potential as antidiabetic agents but also for other possible health benefits.     

Palladium-catalysed 5-endo-trig allylic (hetero)arylation

A palladium-catalysed intramolecular allylic (hetero)arylation strategy for the synthesis of fused cyclopentenes incorporated with all-carbon quaternary and spiro centres is described. The method is straightforward, shows broad scope, proceeds in synthetically useful yields, and provides a rare means to construct complex cyclopentanoids. The reaction is believed to involve a kinetically unfavourable 5-endo-trig carbocyclisation of the tethered (π-allyl)palladium system. Further, this method was successfully applied as the key step in the total synthesis of diterpene natural products taiwaniaquinone H and dichroanone.

A palladium-catalysed intramolecular allylic (hetero)arylation strategy for the synthesis of fused cyclopentenes incorporated with all-carbon quaternary and spiro centres is described.     

Phosphomolybdic acid catalyzed facile one‐pot synthesis of 2,4,5‐triaryl‐1H‐imidazoles from benzil and aromatic aldehydes

A facile one‐pot synthesis of 2,4,5‐triaryl‐1H‐imidazoles with better yields and shorter reaction time from the condensation of benzil, ammonium acetate and aromatic aldehydes using the catalyst phosphomolybdic acid is described     

Synthesis of photocleavable poly(methyl methacrylate‐block‐d‐lactide) via atom‐transfer radical polymerization and ring‐opening polymerization

The synthesis and characterization of a photocleavable block copolymer containing an ortho‐nitrobenzyl (ONB) linker between poly(methyl methacrylate) and poly(d ‐lactide) blocks is presented here. The block copolymers were synthesized via atom transfer radical polymerization (ATRP) of MMA followed by ring‐opening polymerization (ROP) of d ‐Lactide and ROP of d ‐lactide followed by ATRP of MMA from a difunctional photoresponsive ONB initiator, respectively. The challenges and limitations during synthesis of the photocleavable block copolymers using the difunctional photoresponsive ONB initiator are discussed. The photocleavage of the copolymers occurs under mild conditions by simple irradiation with 302 nm wavelength UV light (Relative intensity at 7.6 cm: 1500 μW/cm²) for several hours. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2013, 51, 4309–4316