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I.Introducti0nlnPart(l),thethree-porous-medium1nodeIisdevelopedtosimulatethebLliddynan1icproblem0ftulbormicrocirculation.Thepressureandvel0citypr0fileofblo0d,lyn1phandinterstitialI1uidarcobtaincLl.Basedol1thescsoltltions,tl1ctral1sl,ortpr0ccss()finbbUbOg10bUlb1G(lgG)anditSal1tigCb-bindil1gfraglbCI1t(Fab)iI2thCl1Orn1al-tlSSuC-surroundcdtunlorareana1yzedibthispapcl'.Thel1nitcclcn1el1tlbetl1odisuscdtos0lvethcdit1'usion-convcctiollequatiol1stogcttbccol1cel1trationproIbeoflgGandFabil1bloo… 相似文献
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IntroductionThemostobviouscharacterofatherosclerosisisthelocalintimalaccumulationoflow_densitylipoprotein(LDL) ,theincreaseofthefiberaltissueandthestenosis.Ononehand ,itisfoundthatthediseaseoftenoccursatthecomplexgeometryregion ,suchasbifurcationzone,cure… 相似文献
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冠状动脉狭窄情况下的非牛顿血液流动和大分子传质 总被引:4,自引:1,他引:4
针对冠状动脉狭窄的情况,采用数值模拟方法求解了牛顿流体与非牛顿流体(幂次律流体和Casson流体)的定常与脉动的流场。在此基础上,求解了LDL(低密度脂肪蛋白)和Albumin(血清白蛋白)的浓度场。根据计算结果,详细讨论了壁面剪应力、非牛顿流效应、分子大小等因素对大分子传质的影响;并对牛顿流体与非牛顿流体、定常流动与脉动流动的大分子浓度场进行了比较,这些结果对于了解动脉硬化成因与流动特性和大分子传质的联系提供了较为丰富的信息。 相似文献
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This paper deals with the motion of viscous liquid column with finite length and two free surfaces in a vertical straight capillary tube. It is assumed that fluid is Newtonian. Linearizing the boundary conditions, analytic expressions in the form of infinite series have been obtained for velocity, piessure and free surface at low Reynolds number. The numerical calculation is carried out for a set of cylinder’s length of water and blood. It has been revealed that there are considerable circulating currents at the upper and lower meniscuses. Its maximum velocity is about 57% of the average velocity of the mainstream. Iner-tial effect is also studied in this paper. Using the time-dependent method in finite difference techniques, numerical solution of the corresponding nonlinear equation at Re<24.5 is computed. Comparing it with analytic exact solution at low Reynolds number shows that inertial effect is negligible provided Re<24.5. 相似文献
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This paper deals with the motion of viscous liquid column with finitelength and two free surfaces in a vertical straight capillary tube.It isassumed that fluid is Newtonian.Linearizing the boundary conditions,analytic expressions in the form of infinite series have been obtainedfor velocity,plessure and free surface at low Reynolds number.Thenumerical calculation is carried out for a set of cylinder’s length ofwater and blood.It has been revealed that there are considerable cir-culating currents at the upper and lower meniscuses.Its maximum ve-locity is about57%of the average velocity of the mainstream.Iner-tial effect is also studied in this paper.Using the time-dependent methodin finite difference techniques,numerical solution of the correspondiugnonlinear equation at Re≤24.5 is computed.Comparing it with analyticexact solution at low Reynolds number shows that inertial effect isnegligible provided Re≤24.5. 相似文献
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EFFECTOFMAGNETICFIELDSONVISCOUSLIQUIDCOLUMNWITHFINITELENGTHINAVERTICALSTRAIGHTTUBEWenGong-bi(温功碧);SunKe-li(孙克利)(DepartmentofM... 相似文献
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IntroductionThefluiddynamicsofbloodcyclesystemplayanimportantroleinthepathogenesisofatherosclerosis.ThephysiologicalanatomyfoundthattheatherosclerosisappearsoftenatthebifurcationorcurvedflowareatoallkindsofRefs.[1 ,2 ] .Theshearstressvariesgreatlyinthoseareaandinfluencesthemacromoleculartransportacrossthebloodwall[3,4].Thus ,theinvestigationoftheflowandmacromoleculartransportinthesecomplexbloodvesselaandthecorrelationbetweenthemareinterestingtoresearchers.Intheseaspect,Liepschstudiedtheflowi… 相似文献
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A New Unsteady Three Dimensional Model for Macromolecular Transport and Water Filtration Across the Arterial Wall 总被引:1,自引:0,他引:1
IntroductionAtherogenesis,oneofthemajorcausesforthedeathofpeopleinwesterncountries,hastwoprominentproperties.First,itusuallytakesplaceatthebranchesorcurvaturesofthebigarteries,wherethereisanabruptchangeofbloodflow .Secondly ,thereisanaccumulationoflocalf… 相似文献
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A numerical analysis of the steady/pulsatile flow and macromolecular (such as LDL and Albumin) transport in curved blood vessels was carried out. The computational results predict that the vortex of the secondary flow is time-dependent in the aortic arch. The concentration of macromolecule concentrates at the region of sharp curve, and the wall concentration at the outer part is higher than that at the inner part. Atherosclerosis and thrombosis are prone to develop in such regions with sharp flow. 相似文献