A Study of the Oxidation Pathway of Adrenaline by Cyclic Voltammetry: An Undergraduate Analytical Chemistry Laboratory Exercise

An undergraduate laboratory exercise to be used in an undergraduate instrumental methods course is presented for the electrochemical characterization of oxidation products of adrenaline. An objective of this experiment is to use information obtained through cyclic voltammetry and simulation software to develop a qualitative understanding of the oxidation mechanism of adrenaline.     

PHOTOCHEMICAL INTERACTIONS OF CHLORPROMAZINE WITH PHOSPHOLIPIDS AND CHOLESTEROL IN ARTIFICIAL AND NATURAL MEMBRANES

Abstract— Dipalmitoylphosphatidyl-choline (DPPC) liposomes do not modify the nature of the photoproducts formed by UV irradiation of chlorpromazine. However, when cholesterol is added to DPPC liposomes, new photoproducts are formed which demonstrate the photoaddition of chlorpromazine to cholesterol. Similar results are obtained with phosphatidyl-serine and phosphatidyl-inositol. The reactivity of irradiated chlorpromazine towards lipidic components of myelin, taken as an example of biological membrane, is also demonstrated.     

PROMOT: A Modeling Tool for Chemical Processes

The novel process modeling tool PROMOT supports the object-oriented modeling of chemical processes for the simulation environment DIVA. In PROMOT, differential-algebraic process models can be built by aggregating structural and behavioral modeling entities that represent the topological structure or the dynamic and steady-state behavior, respectively, of the investigated chemical processes. Process models and their modeling entities may be defined either in an object-oriented modeling language or with a graphical user interface. This paper discusses the modeling concept, the modeling language, the knowledge representation aspects, and the implementation of PROMOT.