An efficient and convenient synthesis of pentasubstituted pyrroles from alkyl acetoacetates,dialkyl acetylenedicarboxylates,and amines

A simple and efficient synthesis of pentasubstituted pyrroles has been developed using a one-pot, two-step reaction. The synthesis of a series of 4-hydroxypenta-1,3-diene-tricarboxylates from alkyl acetoacetates and dialkyl acetylenedicarboxylates in the presence of K₂CO₃, followed by cyclization with amines, gave the corresponding pyrroles in excellent yields.     

Efficient regeneration of aldehydes from their corresponding 1,3-oxathiolanes in the absence of solvent

A mild and efficient method for the oxidative deprotection of 1,3-oxathiolanes with Fe（NO₃）₃·9H₂O and Cu（NO₃）₂·3H₂O in the absence of solvent is reported.     

Epoxidation of vinyl cyanides by lithium hypochlorite in the presence of Fe3O4@Ag-CTAB as a new eco-friendly catalyst in aqueous medium

Research on Chemical Intermediates - To cater to the requirement of environmental protection, cetyltrimethylammonium bromide (CTAB)-coated Fe3O4@Ag Nanoparticles as a new hybrid magnetic catalyst...     

Preparation and characterization of Fe3O4@Cu-β-CD as a hybrid magnetic catalyst for the synthesis of dihydropyrano[2,3-c]pyrazoles in H2O

Research on Chemical Intermediates - Fe3O4@Cu-β-CD is a hybrid composite with high catalytic activity. Easy separation with an external magnet and recyclability are the advantages of this...     

Epoxidation of vinyl cyanides by calcium hypochlorite under catalyst- and solvent-free conditions

In this paper, epoxidation of a wide range of alkenes by calcium hypochlorite (Ca(OCl)₂) was investigated under catalyst- and solvent-free conditions. It was noticed that the highest yield was achieved with crushing, when the reaction was between vinyl cyanides and Ca(OCl)₂. The structure of the synthesized epoxides was confirmed by IR, ¹H and ¹³C NMR and elemental analysis. Short reaction times, the use of a simple experimental procedure, and reducing of energy consumption are other important advantages of our work that could be mentioned too.