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Wen PEI* Kobe JOZE College of Chemical Engineering Zhejiang University of Technology Hangzhou National Institute of Chemistry Hajdrihova SI- Ljubljana Slovenia 《中国化学快报》2001,(6)
Much attention is currently focused on the design of new generations of platinum anti-cancer complexes to prevent resistance of cisplatin. We have developed a new platinum-based antitumor agent with broad-spectrum antiviral activity. The cis-[Pt(DMSO)2Cl2] and K[Pt (DMSO) Cl3] reacted with 1-??-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin) and its deoxy-analogue (deoxyribavirin) to give the coordinated complexes which exhibited activity against both DNA and RNA viruses1. The… 相似文献
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