Application of vernier thinning techniques to segmented annular arrays

Due to the aperture periodicity, the inter-element spacing of two-dimensional squared arrays is maintained near lambda/2 in order to avoid grating lobes. This condition gives rise to severe problems derived from the huge number of array elements and from their little size that causes the signal to noise ratio to bring down. Vernier techniques have been proposed to lower the number of active elements, but the drastic reduction of the ultrasonic energy is still a great problem for the image contrast. In this work, vernier techniques for segmented annular (SA) arrays are theoretically studied. SA arrays produce lower grating lobes than squared arrays and, therefore, allow the element size to be increased beyond the lambda/2 constraint. Using larger elements, SA arrays have advantage to squared arrays because they have larger active area and smaller thinning order for the same complexity (number of channels) of the image system. Theoretical results of the vernier techniques applied to SA arrays in both radial and tangential directions are presented and compared with the equivalent squared array.     

Transient stationary waves and angular momentum

We report new transient stationary spherical waves generated by the time evolution of wave functions with angular momentum. In the study the 3D problem of the sudden release of a particle which initially was inside a spherical trap, the exact solution for the particle's time evolution is described by expected traveling incoming and outgoing spherical waves. However, unexpected transient stationary spherical waves are also present. The traveling waves have amplitudes describing diffraction in time, in a way similar to the optical diffraction by a single slit. In striking contrast with the similar 1D problem, the angular momentum generates unexpected transient stationary spherical waves which have their main contribution at points inside the sphere but only for very short times.     

A validated stability-indicating LC method for simultaneous determination of quinapril and hydrochlorothiazide in pharmaceutical samples

A stability-indicating liquid chromatographic method was developed and validated for simultaneous determination of quinapril and hydrochlorothiazide in drug substances and dosage forms. Chromatographic separation of quinapril, hydrochlorothiazide and its degradation products was achieved on a RP-18 column, using acetonitrile and phosphate buffer (pH 4.6) as mobile phase in a gradient mode and detection at 216 nm. Stress testing was performed under hydrolytic, oxidative, thermal and photolytic conditions. The degradation products were well resolved from main peaks, proving the stability-indicating power of the method. The assay was linear for quinapril and hydrochlorothiazide concentrations of 40–200 µg mL^?1 and 25–125 µg mL^?1, respectively. The developed method was selective, accurate and precise for quinapril and hydrochlorothiazide determination. This method was used to quantify both drugs in combined commercial tablets. The results showed that the proposed method was found to be suitable for quantitative determination and the stability study of quinapril and hydrochlorothiazide in pharmaceutical samples.