术前超声双重造影检查对胃癌患者胃周淋巴结转移的评估价值

目的探讨超声双重造影检查（DCUS）在不同部位胃癌术前淋巴结转移评估中的应用价值。方法选择180例胃癌患者,手术前3～5d内均进行DCUS及螺旋CT检查,对不同部位的胃癌患者术前均进行淋巴结分站评估,与术后病理检查结果对照得出正确率,并进行相互间比较。结果 DCUS和螺旋CT检查对远端胃切除患者淋巴结转移判断正确率分别为86.0%和83.9%,对全胃切除患者的判断正确率分别为82.5%和85.0%,两种检查方法判断准确率差异均无统计学意义（P＞0.05）;DCUS对近端胃切除患者淋巴结转移判断正确率为66.0%,明显低于螺旋CT检查的85.1%,差异有统计学意义（均P＜0.05）。结论胃癌术前淋巴结转移评价中,超声双重造影检查判断正确率与螺旋CT相当,仅对贲门胃底部癌判断正确率略低。     

双能CT检查对40例痛风性关节炎患者尿酸盐结晶的临床分析

痛风是一种嘌呤代谢障碍导致血尿酸增高引起的一种代谢性障碍性疾病,而尿酸是以钠盐形式沉积在关节、软组织和肾脏而引起组织的异物炎性反应,一直缺乏简便可靠的诊断方法。双能CT检查能鉴别组织成分、显示特定组织。近年来,国内外多项研究报道双能CT检查在发现关节尿酸盐结晶沉积中具有重要的价值[1-3]。笔者采用双能CT检查检测患者肿痛关节是否存在尿酸盐结晶沉积,探讨双能CT检查在临床诊断痛风性关节炎中的应用价值。     

急性肺栓塞患者血浆脑钠肽与右心功能的关系及其预后评估价值

目的研究血浆脑钠肽（BNP）与急性肺栓塞（APE）患者右心室功能不全（RVD）的关系及其预后评估价值。方法采用酶联免疫法测定44例APE患者血浆BNP水平,同时根据超声心动图检查分为RVD组和无RVD组。观察两组间血浆BNP水平差异及血浆BNP水平与不良事件发生率的关系。结果 APE患者RVD组BNP水平[（2352.5±1987.8）pg/ml]高于无RVD组[（349.9±299.4）pg/ml]（P＜0.01）;低BNP者不良事件发生率（10.0％）低于高BNP者（69.2％）,差异有统计学意义（P＜0.05）;低BNP者1年生存率高于高BNP者（χ2=6.554,P＜0.05）。结论 BNP可作为反应APE患者RVD的有效手段,对预测患者不良事件及预后有重要作用。     

Tregs细胞CCR4、CCR6表达异常在类风湿关节炎患者发病时的意义

目的探讨Tregs细胞CCR4、CCR6受体在类风湿关节炎（RA）患者发病时的意义。方法选择45例活动期RA患者（RA组）及30例健康体检者（对照组）,从外周血分离单个核细胞（PBMC）,采用流式细胞分析法检测RA患者外周血中CD4+Foxp3+细胞（Tregs）占比及其该类细胞上CCR4、CCR6的表达水平,并对Tregs上CCR4、CCR6水平与RA临床活动指标进行相关性分析。结果与对照组比较,RA活动期患者外周血Tregs细胞数量明显减少,差异有统计学意义（P＜0.05）;RA活动期患者外周血Tregs细胞表面趋化因子受体CCR4、CCR6表达水平与对照组的差异有统计学意义（P＜0.05）;RA活动期患者外周血Tregs细胞CCR4、CCR6表达水平与DAS28评分呈正相关（P＜0.05）。结论 RA患者外周血中Tregs细胞上趋化因子受体CCR4、CCR6表达增加,可能是Tregs细胞获得定向迁徙至病变关节能力的表现,也是机体炎症反应时反馈性调节的一种现象。     

超声检查在鼻咽癌放疗后颈动脉损伤中的应用价值

目的探讨超声检查在鼻咽癌放疗后颈动脉损伤中的应用价值。方法接受放疗并随访2年以上的鼻咽癌患者40例作为放疗组,对照组30例为新诊断还未实施放疗的鼻咽癌患者,应用彩色多普勒超声检查,记录患者颈动脉狭窄部位和狭窄程度,主要检测指标有：颈动脉管腔内径,内膜-中层厚度,斑块部位、大小、形态、回声及颈动脉血流情况,同时分析两组间相关危险因素对疾病的影响。结果两组间相关危险因素如年龄、性别、高血压、高脂血症、高血糖、吸烟等差异均无统计学意义（均P＞0.05）,但两组间颈动脉损伤发生率差异有统计学意义（P＜0.05）。放疗组患者内膜-中层厚度明显大于对照组,发生狭窄情况远远高于对照组。颈动脉狭窄率＞50%仅见于放疗组。结论鼻咽癌患者放疗可导致颈动脉的内膜-中层厚度增加、形成斑块继而发生狭窄,而超声检查在颈动脉损伤的早期发现、早期预防及术后疗效评估中具有重要的临床应用价值。     

不同组织多普勒技术对高血压病左心室不同几何构型阶段主动脉壁平滑肌运动定量分析研究

目的探讨应用不同组织多普勒技术评估高血压病不同左心室几何构型阶段主动脉壁平滑肌运动的价值.方法测定高血压病患者主动脉壁的组织速度显像、组织追踪显像、应变显像和应变率显像曲线,并且分别测量每一曲线上的收缩期峰值速度(AOPVs)、舒张早期运动速度(AOVe)、舒张晚期运动速度(AOVa)、收缩期峰值位移(AOPDs)、收缩期峰值应变(AOPSs)、收缩期峰值应变率(AOPSRs)、舒张早期应变率(AOEsr)、舒张晚期应变率(AOAsr);并计算AOVe/AOVa,AOEsr/AOAsr.结果对照组与正常构型组、向心性重构组、向心性肥厚组、离心性肥厚组的AOPSs、AOVe、AOVa、AOEsr、AOEsr/Asr测值,向心性重构组、向心性肥厚组、离心性肥厚组的AOPDs测值,正常构型组、向心性重构组、向心性肥厚组的AOVe/Va测值差异均有统计学意义(均P<0.05);正常构型组与对照组、向心性重构组、向心性肥厚组、离心性肥厚组的AOPVs、AOPDs测值差异均有统计学意义(均P<0.05);向心性重构组与对照组、向心性肥厚组、离心性肥厚组的AOPVs测值,正常构型组、向心性肥厚组、离心性肥厚组的 AOPSs测值差异均有统计学意义(均P<0.05);离心性肥厚组与对照组、正常构型组、向心性重构组、向心性肥厚组的AOAsr、AOVe/Va测值差异均有统计学意义(均P<0.05);正常构型组、离心性肥厚组与对照组、向心性重构组、向心性肥厚组的AOPSRs测值、正常构型组、向心性重构组与向心性肥厚组、离心性肥厚组的AOEsr/Asr测值差异具有统计学意义(均P<0.05).结论(1)组织多普勒技术可评价高血压病不同左心室几何构型阶段的主动脉壁平滑肌的运动;(2)利用组织多普勒参数可定量评估高血压病在不同左心室几何构型阶段主动脉壁平滑肌的功能.     

The calculation of the energy losses in a sliding elastic contact with friction and wear (the plane problem)

The plane problem of the sliding contact of a punch with an elastic foundation when there is friction and wear is considered. Assuming the existence of a steady solution in a moving system of coordinates, relations are derived between the sliding velocity, the wear, the contact stresses and the displacements for an arbitrary dependence of the wear rate on the contact pressure. Taking into account the presence of a deformation component of the friction force, an equation is written for the balance of the mechanical energy for the punch - elastic base system considered. It is shown that the equality of the work of the external force in displacing the punch to the losses due to friction and the change in the shape of the foundation due to wear is satisfied when the work done by the contact stresses on the increments of the boundary displacements is equal to zero, and the frictional losses must be determined taking into account the non-uniformity of the distributions of the shear contact stresses and the sliding velocity in the contact area. Two special cases of the foundation in the form of a wide and narrow strip are considered, for which the total coefficient of friction is calculated, taking into account the deformation component of the friction force.     

Axially symmetric problems of stationary heat conduction and thermoelasticity for a body with thermally active or thermally insulated disk inclusion (crack)

We present solutions of axially symmetric problems of stationary heat conduction and thermoelasticity for a body with a thin thermally active disk inclusion (where the temperature or heat flow is given) and also with a thermally insulated inclusion. The heat conduction problems are reduced to integral equations, and exact solutions are obtained in the case where their right-hand sides are polynomials of arbitrary degree. We determine the components of the stress tensor and displacement vector as well as, in the case of cracks, the stress intensity factors.     

单个函数平移和伸缩的叠加在L~p(R~d)中的逼近(英)

本文主要讨论单个函数平移和伸缩的线性组合对Lp（Rn）中任一紧集内函数的逼近．给出一个很强的逼近结果．这在神经网络应用研究中具有重要意义．     

The property of orthogonality and energy transfer by three-dimensional eigenwaves in transversely isotropic laminated plates with and without contact with a liquid

The properties of eigenwaves in laminated plates with anisotropy in a transforse directon properties are studied. The most general form of the solutions, dispersion relations, power flows and generalized orthogonality relations are analysed. The similarity and difference in the properties of the waves as compared with isotropic media and ideal fluids, as well as the extension to the case of layered spaces and half-spaces, is investigated. A method of determining the coefficients for the eigenwaves radiated in the plate is proposed in the case of a problem with dynamical sources of finite size. A method of summing the series over eigenwaves is suggested.     

新疆14个地州市疾病预防与控制机构服务能力综合评价研究

本文利用主成分分析方法,借助SPSS统计软件建立评价模型,综合评价新疆14个地(州、市)疾病预防控制机构的服务能力进行了综合评价,研究结果提示:新疆14个地(州、市)级疾病预防控制机构中,综合服务能力位列前三位的分别是克拉玛依市、乌鲁木齐市和伊犁哈萨克自治州,位列后三位的分别是克孜勒苏柯尔克孜自治州、和田地区和喀什地区疾病预防控制中心,整体实力北疆地区机构优于南疆地区。