共查询到20条相似文献,搜索用时 22 毫秒
1.
Hui-Feng Huang Cai-Juan Zheng Guang-Ying Chen Wen-Qing Yin Xian Huang Zheng-Rong Mo 《中国化学快报》2016,27(10):1612-1616
Four new sesquiterpenoids,4,8-dioxo-6β-hydroxyl-7β,1 1-epoxycarabrane(1),4,8-dioxo-6β-hydroxyl-7,1 1-epoxycarabrane(2),wenyujinins Q and R(3-4),and nine known sesquiterpenoids(5-13) were isolated from the Curcuma wenyujin(C wenyujin) dreg.Their structures and relative configurations were elucidated using 1D,2D NMR,and HR-ESI-MS data.All the compounds were isolated for the first time from the C.wenyujin dreg and evaluated for their antibacterial and antifungal activities.Compounds 3,5-8 exhibited strong broad-spectrum antifungal activities against tested nine pathogenic fungi. 相似文献
2.
Two new bisabolane-type sesquiterpenoids, (3R,4R,6S)-3,4-epoxybisabola-7(14),10-dien-2-one and (1R,3R,4R,5S,6S)-1-acetoxy-8-angeloyloxy-3,4-epoxy-5-hydroxybisabola-7(14),10-dien-2-one, and a new oplopane-type sesquiterpenoid, 14(R)-hydroxy-7beta-isovaleroyloxyoplop-8(10)-en-2-one, were isolated from Farfarae Flos along with three known compounds. The structures of these compounds were elucidated on the basis of spectroscopic evidence. 相似文献
3.
Zha‐Jun Zhan You‐Min Ying Fu‐Yu Zhang Cheng‐Ping Li Wei‐Guang Shan 《Helvetica chimica acta》2010,93(3):550-554
The chemical investigation of the aerial parts of Pteris semipinnata resulted in the isolation of three illudalane sesquiterpenoids, namely (2R)‐norpterosin B ( 1 ), (2R)‐12‐O‐β‐D ‐glucopyranosylnorpterosin B ( 2 ), and semipterosin A ( 3 ), along with three known compounds. The structures of 1 – 3 were established by spectroscopic methods, including extensive 2D‐NMR and CD analyses. 相似文献
4.
Apart from the well-known constituents (+)-β-selinene ( 2 ), (?)-β-elemene ( 4 ), (+)-β-costol ( 7 ), (?)-caryophyllene ( 17 ), and (?)-elemol ( 19 ) the following sesquiterpenoids have been isolated for the first time from costus root oil (Saussurea lappa CLARKE ): (?)-α-selinene ( 1 ), (+)-selina-4, 11-diene ( 3 ), (?)-α-trans-bergamotene ( 5 ), (?)-α-costol ( 6 ), (+)-γ-costol ( 8 ), (?)-elema-1,3,11 (13)-trien-12-ol ( 9 ), (?)-α-costal ( 11 ), (+)-γ-costal ( 12 ), (+)-γ-costal ( 13 ), (?)-elema-1,3,11 (13)-trien-12-al (elemenal, 14 ), (?)-(E)-trans-bergamota-2, 12-dien-14-al ( 15 ), (?)-ar-curcumene ( 16 ), and (?)-caryophyllene oxide ( 18 ). Compounds 6 , 8 , 9 , and 13 are new sesquiterpenoids. IR. and NMR. spectra of 12 sesquiterpenoids are reproduced. 相似文献
5.
《Tetrahedron: Asymmetry》2007,18(14):1693-1700
Six new sesquiterpenoids and two new norsesquiterpenoids were isolated from the essential oils of three liverworts. The isolated compounds include (+)-eudesma-4,11-dien-8α-ol from the liverwort Diplophyllum albicans, (−)-4β,5β-diacetoxygymnomitr-3(15)-ene, (+)-5β-acetoxygymnomitr-3(15)-ene, (−)-15-acetoxygymnomitr-3-ene, (−)-3β,15β-epoxy-4β-acetoxygymnomitrane, and (−)-3α,15α-epoxy-4β-acetoxygymnomitrane from Marsupella emarginata, and (+)-1,2,3,6-tetrahydro-1,4-dimethylazulene and (−)-2,3,3a,4,5,6-hexahydro-1,4-dimethylazulen-4-ol from Barbilophozia floerkei. These compounds were isolated by a combination of different chromatographic techniques, and their structures were determined by extensive spectroscopic studies (MS, 1H, 13C, and 2D NMR) and chemical transformations using enantioselective GC. 相似文献
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7.
《Tetrahedron: Asymmetry》2007,18(10):1245-1253
Nine new amorphane sesquiterpenoids, (+)-7β-hydroxyamorpha-4,11-diene, (−)-9α-hydroxyamorpha-4,7(11)-diene, (−)-3α-hydroxyamorpha-4,7(11)-diene, (−)-3α-acetoxyamorpha-4,7(11)-diene, (−)-amorpha-4,7(11)-dien-3-one, (+)-2,8-epoxyamorpha-4,7(11)-diene, (+)-5,9-epoxyamorpha-3,7(11)-diene, (−)-2α-hydroxyamorpha-4,7(11)-diene and (−)-2β-acetoxyamorpha-4,7(11)-diene, were isolated from the essential oil of the liverwort Marsupella aquatica, collected near Gaschurn/Montafon, Austria. The isolated compounds and their chemical transformations were investigated using enantioselective GC and extensive spectroscopic studies (HRMS, 1H, 13C and 2D NMR). The absolute configuration of most of the isolated compounds were established by conversions to known compounds. In addition, 1H, and 13C NMR data of (−)-myltayl-4-ene are reported for the first time. 相似文献
8.
Su JH Lu Y Hung WY Huang CY Chiang MY Sung PJ Kuo YH Sheu JH 《Chemical & pharmaceutical bulletin》2011,59(6):698-702
Four new nardosinane-type sesquiterpenoids, flavalins E-H (1-4) and two new nornardosinane-type norsesquiterpenoids, flavalins I (5) and J (6), along with five known compounds (7-11) have been isolated from a Formosan soft coral Lemnalia flava. The structures of these compounds were elucidated on the basis of their spectroscopic data. Moreover, the absolute configuration of 10 was further determined by Mosher's method. 相似文献
9.
Myrrhanolide D and Myrrhasin A,New Germacrane‐Type Sesquiterpenoids from the Resin of Commiphora opobalsamum 下载免费PDF全文
Tao Shen Guo‐Hui Li Qing‐Qing Zhong Shu‐Qi Wang Dong‐Mei Ren Hong‐Xiang Lou Xiao‐Ning Wang 《Helvetica chimica acta》2014,97(6):881-886
Two new germacrane‐type sesquiterpenoids bearing an epoxy ring, myrrhanolide D ( 1 ) and myrrhasin A ( 2 ), together with eight known compounds, 3 – 10 , were isolated from the resinous exudates of Commiphora opobalsamum. Their structures were elucidated based on the analyses of their spectroscopic data. The isolated compounds 1, 2, 6 , and 8 were evaluated for their cytotoxic activities against human prostate cancer DU145 and PC3 cells. 相似文献
10.
Moriyama M Huang JM Yang CS Kubo M Harada K Hioki H Fukuyama Y 《Chemical & pharmaceutical bulletin》2008,56(8):1201-1204
Two new seco-prezizaane-type sesquiterpenoids 1, 2 and two new prenylated phenylpropanoids 4, 5 were isolated along with 15 known compounds from Illicium fargesii. The structures of 1, 2 were elucidated as 10-O-(E)- and 10-O-(Z)-cinnamoyl-2-oxo-6-deoxyneoanisatin by analysis of spectroscopic data and by comparison of their NMR data with those of previously reported 2-oxo-6-deoxyneoanisatin (3), respectively, whereas the structures of 4, 5 were identified as 4-allyl-2-(3-methylbut-2-en-1-yl)phenol and 4-allyl-2-(2-methylbut-3-en-2-yl)phenol, respectively, on the basis of spectroscopic data. Among the isolated compounds, macranthol (7) was found to have neuroprotective activity at 5--10 microM in rat cortical neurons cultured in DMEM/N2 medium. 相似文献
11.
The diethyl ether extract of the Japanese liverwort Metacalypogeia cordifolia yielded five new chroman type derivatives in addition to known sesquiterpenoids. One of the new chroman derivatives was also isolated from the ether extract of another liverwort, Cephalozia otaruensis. Their structures were established by extensive two dimensional (2D) NMR techniques and chemical evidence. They were shown to be 2,2-dimethyl-7-(3-methyl-2-butenyl)-chroman derivatives. This was the first example of the isolation of the chroman-type compounds, although various types of aromatic compounds have been isolated from liverworts. 相似文献
12.
Abiodun Humphrey Adebayo 《中国化学快报》2009,20(8):945-948
Two novel 4,5-secoeudesmane sesquiterpenoids,oxyphyllones A(1) and B(2) were isolated from the fruits of Alpinia oxyphylla.Their structures were established by spectroscopic methods including 1D and 2D NMR spectra.These two compounds are the first example of naturally occurring sesquiterpenoids with a 4,5-secoeudesmane skeleton in the family of Zingiberaceae and oxyphyllone A(1) is the first 4,5-secoeudesmane type of 13-norsesquiterpenoid.Compounds 1 and 2 exhibited no cytotoxicities against three cancer... 相似文献
13.
Wen‐Hao Chen Chang‐Ri Han Yang Hui Da‐Shuai Zhang Xin‐Ming Song Guang‐Ying Chen Xiao‐Ping Song 《Helvetica chimica acta》2015,98(5):724-730
Two new eremophilane‐type sesquiterpenoids, 1α‐hydroxyeremophila‐6,9,11‐trien‐8‐one ( 1 ), 4α‐hydroxyeremophila‐1,9‐diene‐3,8‐dione ( 2 ), and a new friedelane‐type triterpenoid, friedelane‐3α,16β‐diol ( 4 ), along with six known terpenoids, 3 and 5 – 9 , have been isolated from the stems of Drypetes congestiflora. Their structures and relative configurations were elucidated on the basis of detailed spectroscopic analyses and by comparison of their NMR data with those reported in the literature. All of the compounds, 1 – 9 , were isolated for the first time from this species. Compound 3 exhibited moderate cytotoxic activities against the A549 and B16F10 cell lines. 相似文献
14.
Li WJ Cheng XL Liu J Lin RC Wang GL Du SS Liu ZL 《Molecules (Basel, Switzerland)》2012,17(2):1797-1808
Five phenolic compounds, namely N-trans-coumaroyltyramine (1), N-trans-feruloyltyramine (2), N-trans-feruloyloctopamine (3), 5,7-dihydroxy-8-methoxyflavone (4) and (3S)3,5,4'-trihydroxy-7-methoxy-6-methylhomoisoflavanone (5), were isolated from the fibrous roots of Liriope muscari (Liliaceae). Compounds 2-5 were isolated for the first time from the Liriope genus. Their in vitro antioxidant activities were assessed by the DPPH and ABTS scavenging methods with microplate assays. The structure-activity relationships of compounds 1-3 are discussed. 相似文献
15.
Min Guo Ying-Zhong Liang Xiu-Ming Cui Lin-Jiao Shao Yin-Fei Li Xiao-Yan Yang 《Molecules (Basel, Switzerland)》2022,27(10)
Albocimea B-E (1–4), four new sesquiterpenoids, and four known compounds, steperoxide A (5), dankasterone (6), 1H-indole-3-carboxylic acid (7), and (+)-formylanserinone B (8), were isolated from the rice fermentation of the fungus Antrodiella albocinnamomea. The structures of new compounds were elucidated by comprehensive spectroscopic techniques, the planar structures of new compounds were determined by comprehensive spectroscopic techniques, and their absolute configurations were confirmed via gauge-independent atomic orbital calculations (GIAO), calculation of the electronic circular dichroism (ECD), and optical rotation (OR). These were determined by spectroscopic data analysis. 相似文献
16.
Five new compounds were isolated from the roots of Ligularia dentata, including four bisabolane‐type sesquiterpenoids, 1 – 4 , as well a new eudesmane, 5 . The previously isolated 3α,6α,9‐tris(angeloyloxy)‐2α,4β‐dihydroxy‐7,11‐epoxybisabol‐10(15)‐en‐5‐one ( 6 ), when left as an oil in a refrigerator over nine months, gave rise to a mixture of two positional isomers, 7 and 8 . Their formation is rationalized by means of epoxide ring opening and shift of an angeloyl (Ang) group. The structures of compounds 1 – 5, 7 , and 8 were established by in‐depth spectroscopic (UV, CD, IR, 1D‐ and 2D‐NMR) as well as mass‐spectrometric methods. 相似文献
17.
Dong Chun Kim Jeong Ah Kim Byung Sun Min Tae‐Su Jang MinKyun Na Seung Ho Lee 《Helvetica chimica acta》2010,93(4):692-697
Two new guaiane sesquiterpenoids, 11‐(acetyloxy)‐1,8‐dihydroxyguai‐4‐en‐3‐one ( 5 ) and (1α,6β)‐1,6‐dihydroxytorilin ( 6 ), were isolated from the fruits of Torilis japonica (Umbelliferae), along with four known sesquiterpenes, torilin ( 1 ), torilolone ( 2 ), (1β)‐1‐hydroxytorilin ( 3 ), and (1α)‐1‐hydroxytorilin ( 4 ). During the phytochemical investigation, daucosterol, friedelin, and epifriedelanol were also isolated from the plant for the first time. The structures of the new sesquiterpenoids 5 and 6 were determined by comprehensive analyses of MS and NMR spectroscopic data. These isolates were evaluated against human breast cancer cells (MCF‐7) and Lewis lung carcinoma (LLC) cells. Compounds 1, 3 , and 4 exhibited cytotoxic activity against the LLC cells with IC50 values of 31.3, 32.5, and 34.0 μg/ml, respectively. However, no significant cytotoxicity was found against the MCF‐7 cells for any of the compounds tested. 相似文献
18.
Six sesquiterpenoids, (R, 5E)-2, 12-epoxycaryophyll-5-ene (1) , (2 R, 5E)-caryophyll-5-en-12-al (2) , (2S, 5E)-caryophyll-5-en-12-al (3) , isospathulenol (4) , (1R, 5R)- 1,5-epoxysalvial-4(14)-ene (5) , and salvial-4(14)-en-l-one (6) have been identified for the first time in clary sage oil (Salvia sclarea L.). The structures and absolute configurations of 1–6 are corroborated by partial syntheses and their organoleptic properties are discussed. The compounds 5, 6 and mintsulfide (14) possess the rare C-skeleton C , for which the semisystematic name ‘salvialane’ is proposed. The sesquiterpenoids 1–5 are new. 相似文献
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20.
Six sesquiterpenoids 1 – 6 , formally derived from (+)-(S)-nerolidol by oxidative cyclization, have been isolated for the first time from commercial cabreuva oil. Whereas the two tetrahydrofurans 5 and 6 have already been described, the four bicyclic ethers (cabreuva oxides A–D) 1 – 4 are new. The structures of 1 – 4 are confirmed by synthesis and their absolute configurations are shown to be 3S. The organoleptic properties of the synthetic cabreuva oxides are discussed. 相似文献