共查询到20条相似文献,搜索用时 15 毫秒
1.
H Liu H Wu Z Luo J Shen G Kang B Liu Z Wan J Jiang 《Chemistry (Weinheim an der Bergstrasse, Germany)》2012,18(38):11899-11903
Reverse regioselectivity: The first catalytic asymmetric C-1 functionalization of 1,3-dicarbonyl compounds by an aldol reaction is described, which regioselectively affords 6-hydroxyhexane-2,4-dione derivatives as the only product with high optical purity of up to 93?%?ee. Furthermore, this method provides a facile access to enantioenriched oxygen-containing spirooxindoles and spirobutyrolactones from simple commercial available starting materials. 相似文献
2.
N. M. Tanchuk M. M. Vartanyan N. P. Karzhavina S. Ya. Knyazhanskii E. A. Runova É. A. Karakhanov 《Chemistry of Heterocyclic Compounds》1986,22(3):247-250
It has been established that on interaction of ethoxyacetaldehyde with acetyl-acetone, acetoacetic ester, and benzoylacetone in the presence of piperidine acetate, ,-unsaturated compounds are formed, viz., 3-(2-ethoxy)vinyl substituted acetylacetone, acetoacetic ester, and benzoylacetone. Methods are proposed for the synthesis of 2,3,5-trisubstituted 4,5-dihydrofurans in the presence of trifluoroacetic or acetic acids by the cylization of the linear condensation products.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 308–311, March, 1986. 相似文献
3.
A. Gorup M. Kovačič B. Kranjc-Škraba B. Mihelčič S. Simonič B. Stanovnik M. Tišler 《Tetrahedron》1974,30(14):2251-2256
Azidoazoloazines react with 1,3-dicarbonyl compounds to give cycloaddition products, 1,2,3-triazole derivatives, whose structures have been established by chemical transformations and spectroscopic data. 相似文献
4.
A. V. Aksenov I. V. Aksenova A. S. Lyakhovnenko D. A. Lobach 《Russian Chemical Bulletin》2009,58(4):859-861
A method for the synthesis of 1,3-diazapyrenes has been developed based on the reaction of 1H-perimidines with 1,3-dicarbonyl
compounds in polyphosphoric or 70% aq. sulfuric acid. 相似文献
5.
The reaction of 2-methylene-1,3-dicarbonyl compounds (1) with ethyl diazoacetate gave 4,5-dihydro-1H-pyrazole derivatives (2), which were stable for several months at room temperature in good yields. 相似文献
6.
[reaction: see text]. We have discovered a Ni(II)-catalyzed Conia-ene reaction of 1,3-dicarbonyl compounds with alkynes. In the presence of Ni(acac)2 and Yb(OTf)3, various acetylenic 1,3-dicarbonyl compounds underwent Conia-ene reaction to give mono- and bicyclic olefinic cyclopentanes. A mechanism involving the enol-yne-Ni complex formation is proposed and supported by deuterium-labeling experiments. 相似文献
7.
A. V. Zerov T. S. Krupenya A. A. Petrov S. I. Yakimovich 《Russian Journal of Organic Chemistry》2016,52(3):312-318
Carbonic dihydrazide reacted with 2 equiv of trifluoroacetylacetone to give a compound containing 5-hydroxy-4,5-dihydropyrazole and keto enehydrazine fragments. Analogous 2 : 1 condensations of trifluoro-acetylacetone and 4-ethoxy-1,1,1-trifluorobut-3-en-2-one with oxalohydrazide and malonohydrazide afforded bis(5-hydroxy-4,5-dihydropyrazole) structures as two diastereoisomers. 相似文献
8.
Ya. V. Burgart A. S. Fokin I. T. Bazyl' V. I. Saloutin 《Russian Chemical Bulletin》1997,46(5):952-954
The reaction of fluoroalkyl-containing 1,3-dicarbonyl compounds with benzylideneacetone with the use of pyridine or triethylamine
as a catalyst gave new 3-fluoroalkyl-4-ethoxycarbonyl(acyl)-5-phenylcyclohexan-3-ol-I-ones in yields of 16–33%.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 992–994, May, 1997. 相似文献
9.
V. I. Saloutin Z. É. Skryabina Ya. V. Burgart S. V. Kiseleva 《Russian Chemical Bulletin》1992,41(11):2046-2050
In the reaction of fluorinated copper(II) 1,3-diketonates with diethylenetriamine (or triethylenetetramine) in CHCl3, N,N-bis(1,3-aminovinylketones) are formed in 21–35% yields. Fluorine-containing 1,3-diketones and 1,3-ketoesters, upon interaction with polyamines without solvent, undergo acid cleavage, forming the corresponding amides. The copper(II) 1,3-ketoesterates are readily cleaved in CHCl3 at 25°C in excess triethylenetetramine or ethylenediamine.Department of Fine Organic Synthesis, Institute of Organic Chemistry, Ural Branch, Russian Academy of Sciences, 620219 Ekaterinburg. Translated fromIzvestiya Akademii Nauk, Seriya Khimicheskaya, No. 11, pp. 2591–2596, November, 1992. 相似文献
10.
11.
12.
Mladen V. Proštenik Miljenko Dumić Nada Bošnjak 《Monatshefte für Chemie / Chemical Monthly》1980,111(3):771-773
Reaction of 1,3-dicarbonyl compounds with nitryl chloride through substitution on the activated methylene group, resulted in the formation of chloro, dichloro and oximino derivatives.
Die Reaktion der 1,3-Dicarbonylverbindungen mit Nitrylchlorid
Zusammenfassung Umsetzung von 1,3-Dicarbonylverbindungen mit Nitrylchlorid ergab die entsprechende Chloro-, Dichloro- und Oximinoderivate in einer Substitutionsreaktion an der aktivierten Methylengruppe.相似文献
13.
Olga A. Maloshitskaya Valery V. Alekseyev Kirill N. Zelenin Kalevi Pihlaja 《Tetrahedron》2006,62(40):9456-9466
The reaction products of 1,3-butanediamine and 2-methyl-2,4-pentanediamine with β-keto aldehydes were shown by 1H and 13C NMR spectroscopy to exist as tautomeric mixtures in solutions, comprising one cyclic and two open-chain forms due to the non-equivalence of the amino groups. The chain products exist as Z- and E-isomers. After equilibration, the products from 1,3-butanediamine contain relatively less of the cyclic form than those from 2-methyl-2,4-pentanediamine. The products of 2-methyl-2,4-pentanediamine with p-substituted aroylacetaldehydes, exhibit a linear correlation between log K of the ring-chain equilibria and Hammett's σ values of the aromatic ring substituents. α-Substitution of β-keto aldehydes notably increased the relative amounts of the chain E-isomers in their condensation products and also resulted in the formation of two diastereomers for each of the cyclic products. No ring-chain equilibria were observed in the products of 1,3-butanediamine and 2-methyl-2,4-pentanediamine with β-diketones, β-keto esters, or β-keto amides. 相似文献
14.
15.
16.
A Cu(Ⅰ)-catalyzed one-pot tandem reaction of 2-bromobenzyl bromides with 1,3-dicarbonyl compounds leading to 4H-chromene derivatives has been developed.This new approach toward 4H-chromenes combines several reactions in one pot and builds molecular complexity from readily available starting materials. 相似文献
17.
18.
19.
Dorota Pruka?a 《Tetrahedron letters》2006,47(51):9045-9047
The Mannich reaction of cytosine, paraformaldehyde and cyclic secondary amines in the presence of acetic acid gives 5-(4′-morpholinyl)methylcytosine, 5-(1′-piperidinyl)methylcytosine, 5-(1′-pyrrolidinyl)methylcytosine, 5-(4′-methyl-1′-piperidinyl)methylcytosine, 5-(3′-methyl-1′-piperidinyl)methylcytosine and 5-(2′-methyl-1′-piperidinyl)methylcytosine. These products are quite different from those obtained via cytosine aminomethylation previously described in the literature. 相似文献