非经典稠合噻吩: 噻吩并[3,4-c]噻吩研究进展

具有10π-电子的噻吩并[3,4-c]噻吩体系, 由于其非经典的电子结构, 引起了很大的兴趣. 本工作综述了噻吩并[3,4-c]噻吩的合成和化学性质研究进展.     

3-取代和3,4-二取代噻吩的合成与表征

以噻吩、48% (m/m)氢溴酸水溶液、35% (m/m)过氧化氢水溶液、高纯氨、金属钠为原料合成了3-溴噻吩和3,4-二溴噻吩,3-溴噻吩和3,4-二溴噻吩分别以(dppp)NiCl2为催化剂合成了3-烷基噻吩和3,4-二烷基噻吩.3-溴噻吩以CuI, NaHSO4为催化剂合成了3-烷氧基噻吩,产率较高.并用核磁共振谱、质谱和元素分析方法进行了表征.     

聚噻吩及其衍生物在生物医学领域的应用

做为导电聚合物(CPs)中的重要一类,聚噻吩及其衍生物在电学和光学上显示出了同金属和无机半导体相似的性质.同时也显示出了不同于一般聚合物的特殊性质,如合成和处理容易等.本综述概述了近二十年来聚噻吩及其衍生物的研究进展,包括聚噻吩及其衍生物的合成、性质,以及其在生物医学领域,包括在神经探针和生物传感器中的应用.其中,对聚噻吩在神经探针方面的应用做了重点阐述.本文还对今后聚噻吩及其衍生物在生物医学领域的研究提出了一些具有挑战性的问题.     

两种非对称芳基二噻吩并[2,3-b:3',2'-d]噻吩的合成与光谱特性

合成了两种非对称芳基取代的并三噻吩化合物.以2-溴-5-三甲基硅-二噻吩并[2,3-b:3′,2′-d]噻吩为原料,经脱除四甲基硅烷(TMS)和Suzuki偶联两步反应制备了2-噻吩基二噻吩并[2,3-b:3′,2′-d]噻吩,总产率为67.4%;以2-苯基二噻吩并[2,3-b:3′,2′-d]噻吩为原料,经N-溴代琥珀酰亚胺(简称NBS)溴代和Suzuki偶联两步反应制备了2-苯-5-噻吩基二噻吩并[2,3-b:3′,2′-d]噻吩,总产率为27.8%.产物经核磁共振谱(1H NMR,13C NMR)和质谱(MS)分析确认;利用紫外-可见分光光度法(UV-Vis)分析了合成产物的荧光特性.结果表明,由于苯基的存在,2-噻吩-5-苯基二噻吩并[2,3-b:3′,2′-d]噻吩分子的共轭体系增大,导致其吸收峰红移、发光能力减弱.     

噻吩—2,5—二羧酸的合成新方法

噻吩-2,5-二羧酸是合成双(苯并(口恶)唑基)噻吩型荧光增白剂(如:EBF、OB等)的重要中间体。该类荧光增白剂主要应用于塑料和合成纤维的增白,是国内急待开发的新品种。据文献报道,噻吩-2,5-二羧酸的合成,以己二酸和氯化亚砜为原料,主要有两种合成方法:a多步法,b-步法。我们认为一步法更好,不仅比多步法收率高(多步法收率在38％左右,一步法收率达49％),而且容易工业     

聚丁基噻吩的合成及性能

用化学聚合方法合成了聚丁基噻吩导电材料,并研究了不同的聚合条件对聚合物性能的影响。聚丁基噻吩导电材料具有较好的稳定性和加工性,其掺杂态的导电率可达到10s/cm。     

两种非对称芳基二噻吩并[2,3-b:3',2'-d]噻吩的合成与光谱特性

合成了两种非对称芳基取代的并三噻吩化合物.以2-溴-5-三甲基硅-二噻吩并[2,3-b:3',2'-d]噻吩为原料,经脱除四甲基硅烷(TMS)和Suzuki偶联两步反应制备了2-噻吩基二噻吩并[2,3-b:3',2'-d]噻吩,总产率为67.4%;以2-苯基二噻吩并[2,3-b:3',2'-d]噻吩为原料,经N-溴代琥...     

支链带有富勒烯的聚噻吩和齐聚噻吩及其光伏电池研究进展

可溶性聚噻吩和富勒烯(主要是C60)及其衍生物,是聚合物太阳能电池中被广泛使用的给体和受体材料,它们之间的相容性和富勒烯的聚集效应对于太阳能电池能量转换效率有很大影响。将富勒烯与聚噻吩通过共价键连接在一起,可解决它们的共混膜中的相分离问题,有望提高器件效率,是未来有机和聚合物光伏材料研究的一个重要方向。本文按主链是聚噻吩或齐聚噻吩将这种连有富勒烯的材料分为两类,介绍了这些材料的合成方法、电化学性质及基于这些材料的太阳能电池器件近几年来的研究进展。     

有机噻吩类衍生物作为电致变色材料*

噻吩类衍生物包括聚噻吩衍生物和齐聚噻吩衍生物。本文从有目的地设计、合成噻吩类衍生物的角度出发,探索了其作为电致变色材料的应用,综述了噻吩类衍生物作为电致变色材料的最新研究进展。     

多组分一锅法合成多取代噻吩衍生物

噻吩骨架存在于噻氯匹定、奥莫替尼以及替诺立定等药物中,可用作抗血栓药、抗肿瘤药和消炎镇痛药.目前,对该骨架分子的修饰研究一直是药物合成的热点之一.本文报道了一种在碳酸钾存在条件下,由1,3-二羰基化合物、二硫化碳、溴乙烷以及溴乙腈,通过连续多组分“一锅”反应合成多取代噻吩类化合物的新方法.通过核磁共振波谱和质谱对所得化合物的结构进行了表征,并探讨了该合成反应的机理.该合成方法条件温和、操作安全且收率高.     

N-未取代和N-芳基取代的富勒烯吡咯啉：富勒烯官能团化的新的合成砌块

C₆₀, 甘氨酸或N-芳基化的甘氨酸以及脂肪醛或酮在回流的甲苯或氯苯中反应, 制备出两个系列的稳定的可溶性的富勒烯四氢吡咯衍生物. 这些新的富勒烯衍生物可以作为有用的前体制备更加官能团化的富勒烯衍生物.     

Bis-arylsulfonamide Derivatives of 2-Amino-5(6)-(4-aminophenylthio)benzimidazole

Three different procedures have been developed for the preparation of bis-arylsulfonamide derivatives of 2-amino-5(6)-(4-aminophenylthio)benzimidazole, and biological activity of the products have been studied.     

Chemistry of pyrones related to dehydroacetic acid. Functionalization at C-5 and at the methyl group at C-6. An attempted synthesis of a thromboxane B2 analogue

New derivatives of dehydroacetic acid and triacetic acid lactone functionalized at both C-5 and at the methyl group at C-6 have been synthesized as intermediates for the preparation of thromboxane B₂ analogues. 6-Mercaptomethyl-4-methoxy-2-pyrone and some derived thioethers have been also prepared. New thioether derivatives of O-alkyloximes of dehydroacetic acid have been synthesized and tested for herbicidal activity.     

Synthesis of functionalised polyethylene glycol derivatives of naproxen for biomedical applications

The preparation of a series of mono-naproxen functionalised polyethylene glycol derivatives have been achieved. These compounds feature several different terminal functional groups, the identities of which have been chosen to facilitate conjugation of these hybrid molecules to nanomaterials.     

Zur Reaktion von Halogenwasserstoffen mit Phenyldisilanen

The removal of phenyl groups from disilane derivatives with HCl and HBr to form silicon-halogen bonds has been studied in a variety of methylphenyldisilanes to establish the possible range of application. Besides the preparation of several new compounds, a convenient method is described for the synthesis of certain disilane derivatives which have until now been accessible only with difficulty.     

Annulations of isoquinoline and β-carboline ring systems: synthesis of 8-oxoprotoberberine derivatives

Annulation processes of isoquinoline and β-carboline compounds have been investigated leading to synthetic routes for the preparation of 8-oxoprotoberberine derivatives. The key steps combined a diene formation/Diels-Alder cycloaddition reaction to afford the targeted polycyclic skeletons. Further oxidative transformations of the cycloadducts produced the 8-oxoprotoberberine type products. The alkaloids of this class are important natural products with a wide range of biological activity and the synthethic methodology described in this paper could prove to be useful for the preparation of the D-ring functionalised derivatives.     

Derivatives of 2-(3'-coumarinyl)-1, 3-indandione

The possibility of the direct preparation of 2-(3'-coumarinyl)-1,3-indandione and its derivatives by condensing phthalic and substituted phthalic anhydrides with 3-coumarinylacetic acid in acetic anhydride solution in the presence of triethylamine has been shown. The bromination and hydroxymethylation of 2-(3'coumarinyl)-1,3-indandione and its substituted derivatives have been performed.     

Metal-Organic Framework Composites and Their Derivatives as Efficient Electrodes for Energy Storage Applications: Recent Progress and Future Perspectives

Metal-organic frameworks (MOFs) have been important electrochemical energy storage (EES) materials because of their rich species, large specific surface area, high porosity and rich active sites. Nevertheless, the poor conductivity, low mechanical and electrochemical stability of pristine MOFs have hindered their further applications. Although single component MOF derivatives have higher conductivity, self-aggregation often occurs during preparation. Composite design can overcome the shortcomings of MOFs and derivatives and create synergistic effects, resulting in improved electrochemical properties for EES. In this review, recent applications of MOF composites and derivatives as electrodes in different types of batteries and supercapacitors are critically discussed. The advantages, challenges, and future perspectives of MOF composites and derivatives have been given. This review may guide the development of high-performance MOF composites and derivatives in the field of EES.     

N-酰基氨基酸系列表面活性剂的合成和应用

本文综合评述和介绍了N－酰基氨基酸系列表面活性剂的合成及应用（特别在农业、生物化学和药物制造领域的应用）的一些近年来的研究,进展指出了进一步的研究方向,并报道了我公司开发此类产品的情况。     

Engineering Te-Containing Recognition Modules for Chalcogen Bonding: Towards Supramolecular Polymeric Materials

Aiming at the preparation of one-dimensional (1D) chalcogen-bonded supramolecular polymers at the solid state, this work describes the different syntheses which have been challenged to obtain ditopic molecular modules. At first, tellurazolopyridyl (TZP) rings have been chosen as recognition units, given their well-proven ability and persistency to self-assemble through double Te⋅⋅⋅N chalcogen bonds (ChBs). The second synthetic strategy dealt with the preparation of pyridyl-modified ebselen Te-containing analogues. By attempting several synthetic protocols, the targeted ebselen derivatives could not be obtained, whereas an unexpected Te-containing lactone as well as a spiro-type Te(IV)-containing derivatives were isolated, with the latter investigated by X-ray diffraction (XRD) analysis.