Comparative study of reductive amination reaction on 5-(4-formyl-3,5-dimethoxyphenoxy)valeric acid and its monomethoxy analog using the Multipin™ approach

The 5-(4-formyl-3,5-dimethoxyphenoxy)valeric acid (Barany)linker and its monomethoxy analog were applied to theMultipin method of solid phase synthesis. Acomparative assessment of reductive amination and cleavage ofthese linkers under conditions of multiple synthesis indicatedthat both were applicable to a broad range of primary aminesincluding aniline and 4-nitroaniline. Apart from the greaterlability of the dimethoxy version under TFA cleavage, there wasno observable advantage of one linker over the other within thedescribed experiment.     

The Influence of Relative Content of a Metal Component in a Dielectric Matrix on the Formation and Dimensions of Cobalt Nanocrystallites in Cox(MgF2)100 – x Film Composites

Physics of the Solid State - The influence of relative content of a metal component on the phase composition and substructure of Cox(MgF2)100 – x in a wide range of x =...