Hydrothermal Synthesis, Crystal Structure and Magnetic Properties of a Novel Cobalt Complex Based on Biphenyl-3,3'',4,4''-tetracarboxylate

A novel cobalt complex,[Co2(bptc)(bix)1.5](1,H4bptc=3,3',4,4'-biphenyltetra-carboxylic acid,bix = 1,4-bis(imidazol-1-ylmethyl)benzene),has been hydrothermally prepared and characterized by IR spectroscopy,elemental analysis and single-crystal X-ray diffraction.The crystal is of triclinic system,space group P1 with a=10.770(7),b=12.245(8),c=13.514(9),α=102.829(8),β=107.734(8),γ=98.833(9)°,C37H27N6O8Co2,Mr=801.51,V=1607.5(18)3,Dc=1.656g/cm3,F(000)=818,μ=1.100mm-1,Z=2,the final R = 0.0694 and wR = 0.1543 for...     

Synthesis,Crystal Structure and Catalytic Properties of a 2D Cobalt(Ⅱ) Coordination Polymer Based on Mixed Ligands

A new Co(II) metal-organic coordination polymer based on flexible bis(imidazole) and aromatic dicarboxylate co-ligands, namely [Co(bix)(nph)]n(H2nph = 3-nitrophthalic acid, bix = 1,4-bis(imidazole-1-ylmethyl)benzene), has been hydrothermally synthesized and characterized by elemental analyses, TG, IR spectroscopy and single-crystal X-ray diffraction. It crystallizes in the triclinic space group P1 with a = 9.3767(14), b = 10.1451(15), c = 12.1488(17), α = 102.6450(10), β = 108.856(2), γ = 98.807(2)°, V = 1035.3(3)3, Z = 2, C22H17 Co N5O6, Mr = 506.34, Dc = 1.624 g/cm3, μ = 0.882 mm-1 and F(000) = 518. In the complex, the nph2- ligands connect neighbouring cobalt atoms to form binuclear [Co(nph)]2 subunits, which are linked by pairs of bix ligands to form a 2D honeycomb-like(6,3) network. In addition, the compound is further extended into a 3D supramolecular architecture by π···π stacking interactions. Moreover, the luminescence and catalytic properties of the complex are investigated.     

Hydrothermal Synthesis and Crystal Structure of One 3D Coordination Polymer of Cobalt(II) Achieved from 1,1′-Biphenyl-2,2′,6,6′-tetracarboxylic Acid Ligand

<正>A new three-dimensional coordination polymer {[Co(BPTC)_(0.5)(bix)]·(H_2O)}_n (1, H4BPTC = 1,1′-biphenyl-2,2′,6,6′-tetracarboxylic acid, bix = 1,3-bis(imidazol-1-ylmethyl)-benzene) has been synthesized by the hydrothermal method and characterized by IR, elemental analysis, and single-crystal X-ray analysis. The crystal is of orthorhombic, space group Pbcn with a = 13.2975(10), b = 13.8424(12), c = 22.6367(17), CoC_(22)H_(19)N_4O_5, M_r = 478.34, V = 4166.7(6) ~3, D_c = 1.525 g/cm~3, F(000) = 1968, μ = 0.867 mm~(-1), S = 1.023 and Z = 8. The final R = 0.0683 and wR = 0.1529 for 3655 observed reflections with I > 2σ(I). In the title complex, the 2D Co-BPTC layer is formed through self-assembly of Co(II) ions and bridging BPTC~(4-) ligands in a molar ratio of 2:1. The metal-organic lattice layers are further united together through the second bridging ligand bix to form a 3D metal-organic framework. The thermal stability of the title complex was studied by thermal gravimetric (TG) and differential thermal analysis (DTA).     

Synthesis and Characterization of a New Ligand 2-（4, 5-Dihydro-2-thiazolyl）-6-methoxylbenzothiazole and Its Dinuclear Co（II） Complex

A new ligand 2-(4,5-dihydro-2-thiazolyl)-6-methoxyl benzothiazole and its new dinuclear Co(II) coordination complex [Co(C11H10N2OS2)Cl2]2·2CHCl3 (1) have been synthesized and characterized. Complex 1 was synthesized by the reaction of Co(II) salt with 2-(4,5-dihydro- 2-thiazolyl)-6-methoxyl benzothiazole under room-temperature evaporation condition and struc- turally characterized by single-crystal X-ray diffraction analysis and IR spectroscopy. The supramolecular network of complex 1 is stabilized by the presence of intermolecular interaction, such as C–H···Cl hydrogen bonding and π-π stacking. The complex crystallizes in triclinic, space group P1 with a = 8.3288(12), b = 10.5273(15), c = 10.822(2), α = 93.416(3), β = 90.864(3), γ = 94.890(3)o, V = 943.60(2)3, Z = 2, Dc = 1.758 g/cm3, F(000) = 498 and μ = 1.840 mm-1. The final complex [Co(C11H10N2OS2)Cl2]2·2CHCl3 is a diplex bridged dinuclear complex consisting of two Co(II) ions, two ligands, two bridging Cl- anions and two terminal Cl- anions.     

Hydrothermal Synthesis and Crystal Structure of a 1D Cu（II） Coordination Polymer： [Cu（bbpy）（H_2bptc）]_n Constructed by a Tetracarboxylic Acid

The title compound [Cu(bbpy)(H2bptc)]n (bbpy = 4,4'-dimethyl-2,2'-bipyridine and H4bptc = 1,1'-biphenyl-2,2?,3,3'-tetracarboxylic acid) has been synthesized by hydrothermal reaction, and its structure was determined by X-ray diffraction and characterized by elemental analysis, IR spectrum and thermogravimetric analysis. The crystal is of triclinic, space group P1 with a = 11.2831(12), b = 11.6718(13), c = 11.7771(13), α = 105.392(2), β = 108.382(2), γ = 112.397(2)o, CuC28H20N2O8, Mr = 576.00, V = 1222.4(2)3, Dc = 1.565 g/cm3, F(000) = 590, μ = 0.951 mm-1, S = 1.022 and Z = 2. The final refinement gave R = 0.0405 and wR = 0.1142 for 4270 observed reflections with I > 2σ(I). The title complex has a 1D [Cu(bbpy)(H2bptc)]n chain structure, in which the extensive hydrogen-bond interactions make the chain more stable. The neighboring parallel chains are further packed into a 2D layer structure via π···π stacking interaction between the pyridine rings of bbpy ligands. Moreover, the adjacent layers are interconnected by the C-H···π interactions to form a 3D metal-organic framework.     

Crystal Structure and Properties of a Copper(Ⅱ) Complex Containing p-Toluenesulfonate and Imidazole Ligands

A novel supramolecular mixed ligand complex of formula [Cu(PTS)2(Him)2(H2O)2] (C20H26CuN4O8S2,PTS=p-toluenesulfonate,Him=imidazole) has been synthesized in aqueous solution and characterized by elemental analysis,IR and single-crystal X-ray diffraction.The compound crystallizes in the monoclinic system,space group P21/n,Z=2,a=5.650(2),b=14.671(3),c=14.638(3),β=100.10(3)°,V=1194.60(4)3,Dc=1.607 g/cm3,μ(MoKα)=1.143 mm-1,F(000)=598,R=0.0615 and wR=0.1503 for 1752 observed reflections with I 2σ(I).The copper(II) ion in the complex adopts a slightly distorted octahedral coordination geometry and is six-coordinated with N2O4 donor set consisting of two nitrogen atoms and four oxygen atoms provided by the ligands of two imidazole molecules,two water molecules and two p-toluenesulfonate ions.The sulfonate group of the PTS ligand remains weak-coordinated and forms a number of hydrogen bonds with water molecules and imidazole ligands.X-ray structural analysis reveals that the coordination molecules are connected to form a 3-D supramolecular framework by electrostatic interaction,weak van der Waals forces,hydrogen bonding and π-π interaction.The thermal behaviour of the title complex was investigated by using DSC and TG-DTG techniques.     

A High Dimensional Coordination Polymer Based on [β-Mo8O26]4- Inorganic Building Block： Synthesis, Structure and Topology

A high dimensional copper coordination polymer {[Cu2(btb)2(H2O)4( -Mo8O26)] H2O}n(1, btb = 1,4-bis(1,2,4-triazol-1-yl)butane) based on [ -Mo8O26]4 anions and flexible bis(triazole) ligands has been synthesized and characterized by elemental analysis, IR spectra, single-crystal X-ray diffraction and thermal analysis. The crystallographic data show that complex 1 crystallizes in triclinic space group P with a = 9.7550(10), b = 10.3996(11), c = 10.9516(11), = 77.622(2), = 89.602(2), = 87.610(2), V = 1084.25(19)3, C16H34Cu2Mo8 N12O31, Mr = 1785.15, Dc = 2.734 g cm 3, μ(MoKα) = 3.303 mm 1, F(000) = 856, GOF = 1.060, Z = 1, the final R = 0.0376 and wR = 0.0982 for I > 2 (I). In 1, the inorganic building block [ -Mo8O26]4 anions are connected with each other to generate one-dimensional chains. Then the chains are further connected by Cu2+ ions to form a three-dimensional (3D) inorganic framework [Cu2( -Mo8O26)]n containing quadrangular channels, with the pcu alpha-Po primitive cubic topology. The btb ligands are encapsulated into the void of the 3D inorganic framework forming a new three-dimensional architecture. The thermal analysis illustrates that complex 1 retains a comparatively good thermal stability.     

Synthesis and Crystal Structure of a Novel 2-Fold Interpenetrating Three-dimensional Coordination Polymer,{[Co_3（byip）_2（bix）_3（H_2O）_2]·H_2O}_n

The title coordination polymer including two crystallographically independent Co2+ ions is hydrothermally synthesized, in which the Co(1) 2+ ion is four-coordinated by two carboxylate oxygen atoms from two different 5-(benzoic acid-4-yldiazenyl)isophthalate (byip3-) anions and two nitrogen atoms from two distinct 1,4-bis(imidazol-1-ylmethyl) benzene (bix) ligands displaying a tetrahedral geometry. The Co(2) 2+ ion is six-coordinated by two water molecules at the apical positions, and two carboxylate oxygen atoms and two nitrogen atoms at the equatorial positions, affording a slightly distorted octahedron. Two Co(1)2+ and two Co(2)2+ ions are linked together by four byip3- anions forming a 44-membered motif and these motifs are further arranged into a three-dimensional framework through bix ligands along the a axis with a larger channel (ca. 22.70×11.01). Each individual network interpenetrates with the other identical network in a parallel fashion to generate a 2-fold interpenetrating array with the {62.84}{63}2{64.82}2 topology.     

咪唑配合物[Co(C3H4N2)6](PhCHCHCOO)2的合成及晶体结构

The complex [Co(Im)6](Cin)2 (Im=imidazole,Cin=cinnamate) was prepared by reaction of Co(PhCHCHCOO)2 with imidazole in ethanol. It has been determined by single crystal X-ray analyses. The crystals are triclinic, space group P, with a=9.7601(3),b=10.5935(3),c=11.3269(2)(A),α =69.948(1),β =71.027(1),γ =62.803(1)°, and Z=1. The crystal structure of the title complex consists of monomeric [Co(Im)6]2+ cations and cinnamate anions in which the cobalt(Ⅱ) ion assumes a centrosymmetric octahedral geometry with the CoN6 chromophore. In the solid state, the complex forms a three dimensional network through N-H… O hydrogen bonds, the intermolecular hydrogen bonds connect the [Co(Im)6]2+ cations and cinnamate anions.The cinnamate anions are nearly planar.     

Synthesis, Crystal Structure and Properties of a Dinuclear Cobalt（II） Complex [Co2（a-furacrylato）4（Phen）2（H2O）]·C2H5OH

A dinuclear cobalt(Ⅱ) complex [Co2(α-furacrylato)4(Phen)2(H2O)]·C2H5OH has been synthesized with α-furacrylic acid and 1,10-phenanthroline as the ligands, and its crystal structure was determined. The crystal is of monoclinic system, space group C2/c with a=1.07388(8), b=2.4300(2), c=1.86708(14)nm, β=104.3830(10)o, V=4.719.4(7) nm3 , Dc=1.503 g/cm3 , Z=2, F(000)=2196, GOOF=1.053, the final R=0.0343 and wR=0.0883. The crystal structure shows that two neighboring cobalt(Ⅱ) ions are linked by the bridging coordination of two α-furacrylic acid anions and one water molecule, and their end positions are respectively coordinated with two 1,10-phenanthroline molecules and two α-furacrylic acid anions, forming a dinuclear structure. Both cobalt(Ⅱ) ions adopt hexa-coordinated distorted octahedral geometry. The electrochemical and fluorescence properties of the title complex are also discussed.     

Synthesis and Crystal Structure of a Two-dimensional Cobalt Complex with 5-Tert-butyl Isophthalic Acid

The self-assembly of Co(OAc)·4H2O with H2tbip and bipy (H2tbip = 5-tert-butyl isophthalic acid, bipy = 4,4'-bipyridine) generates one new complex, [Co3(tbip)2(Htbip)2(bipy)]n, which has been characterized by elemental analysis, X-ray diffraction, and IR spectroscopy. Single-crystal X-ray analysis reveals that it crystallizes in the triclinic space group P1 with a = 9.471(6), b = 12.597(8), c = 12.899(8), α = 84.660(7), β = 70.548(7), γ = 81.965(7)o, V = 1435.1(15)3, Mr = 1215.85, Dc = 1.407 g/cm3, Z = 1, F(000) = 629, μ(MoKα) = 0.926 mm-1, the final R = 0.0623 and wR = 0.1724. The complex consists of a tbip bridged trinuclear cobalt() unit and is further linked by 4,4'-bipyridine molecule to form a 2D supramolecular network.     

Synthesis,Structure,Fluorescent Property and Natural Bond Orbital（NBO） Analysis of a One-dimensional Cobalt（III） Complex Containing 1,3-Benzenedicarboxylate and 2-Methyldipyrido[3,2-f：2＇,3＇-h]quinoxaline Ligand

A novel metal-organic coordination polymer [Co(m-BDC)(Medpq)·2H2O]n(m-H2BDC = benzene-1,3-dicarboxyalic acid,Medpq = 2-methyldipyrido[3,2-f:2',3'-h]quinoxaline) has been hydrothermally synthesized and structurally characterized by elemental analysis,IR spectrum and single-crystal X-ray diffraction.The title compound crystallizes in monoclinic,space group C2/c with a = 19.986(4),b = 15.789(3),c = 16.292(3),β = 126.54(3)°,V = 4130.3(14)3,C23H18N4O6Co,Mr = 505.34,Dc = 1.625 g·cm-3,Z = 8,μ = 0.883 mm-1,F(000) = 2072,the final R = 0.0772 and wR = 0.1428.The crystal structure of complex 1 is an infinite zigzag-like chain of hexacoordinate Co3+ ions,in which the Co3+ ions are bridged in two coordination modes by m-BDC2+ ligands and decorated by Medpq ligands,showing a slightly distorted octahedral geometry.Additionally,the compound shows strong fluorescence in the solid state at room temperature.Natural bond orbital(NBO) analysis is performed by using the NBO method built in Gaussian 03 Program.The calculation results show a covalent interaction between the coordinated atoms and Co3+ ions.     

Synthesis,Structure and Spectral Properties of a Novel Triaryl Substituted Triazole and Its Co(Ⅱ) Complex

The new compound 3-(2-pyridyl)-4-(p-methoxyphenyl)-5-(2-thienyl)-1,2,4-triazole L was synthesized and characterized by elemental analysis,IR,1H NMR,13C NMR,MS,UV and photoluminescent spectra.The complex CoL2(NCS)2 was prepared by the reaction of ligand L with Co(SCN)2,and its structure was characterized by single-crystal X-ray diffraction,IR,UV,elemental analysis and MS.The complex crystallizes in monoclinic,space group P21/n with a=13.7639(19),b=7.6641(11),c=18.409(3),β=101.549(3)o,V = 1902.6(5) 3,Z=2,C38H28CoN10O2S4,Mr=843.87,Dc=1.473 g/cm3,μ=0.720 mm-1,S=1.075,F(000)=866.0,the final R=0.0825 and wR=0.2149 for 2566 observed reflections(I2σ(I)).In the crystal structure,the cobalt atom adopts a distorted octahedral environment with two NCS-ions in the axial positions and two bidentate chelating L ligands in the equatorial plane.The extended 2D network of the complex is formed by intermolecular C-H…N hydrogen bonds together with π-π stacking interactions.     

Solvothermal Synthesis and Crystal Structure of a Zn（II） Microporous Metal-organic Framework

A novel three-dimensional Zn(Ⅱ) coordination polymer, Zn3(C2H2N3)4(SiF6), has been synthesized under solvothermal conditions using 1H-1,2,4-triazole-3-carboxylic acid and zinc fluoride as the starting materials. The complex has been characterized by elemental analysis, IR, TG analysis and single-crystal X-ray diffraction analysis. The complex crystallizes in the tetragonal I4/mmm space group with a=11.592(0), c=7.526(1), V=1011.3(2)3 , Z=2, Mr=610.46, Dc=2.005 g/cm3 and F(000)=596. The final R=0.0312 and wR=0.067 for 319 observed reflections with I>2σ(I). In the title complex, the Zn centers are interconnected by μ 3 -bridging triazole ligands to form a microporous three-dimensional metal-organic framework.     

Synthesis,Crystal Structure and Electrochemical Properties of a Cobalt Compound Based on N-（4-pyridylmethyl）imidazole Ligand①

One compound with N-(4-pyridylmethyl)imidazole liand, [Co(pyim)2(N3)2]n 1(pyim = N-(4-pyridylmethyl)imidazole), was synthesized and structurally characterized. Compound 1 crystallizes in triclinic, space group P21/c with a = 8.090(3), b = 16.109(3), c = 8.590(3), B= 117.800(12)o, V = 990.3(5) A3, Z = 2, Mr = 461.37, Dc = 1.547 g/cm3, F(000) = 474, μ = 0.901 mm-1, the final R = 0.0381 and wR = 0.0950 for 1581 observed reflections with I 2A(I). In this compound, the unique Co(Ⅱ) resides at a crystallographic inversion center and exhibits an octahedral coordination geometry. The adjacent Co(Ⅱ) ions are connected by the pyim ligands to form a 2D layer structure. The layers are stacked in an ABAB mode and reinforced by the weak interlayer C–H···N hydrogen bonds and π-π stacking to give a 3D architecture. The thermal property and electrochemical property of compound 1 have also been studied.     

Hydrothermal Synthesis, Crystal Structure and Magnetic Property of a Novel Pentanuclear Copper(Ⅱ) Complex: [Cu5(SIP)2(HSIP)2(H2O)18](H2O)5

The pentanuclear complex, [Cu5(SIP)2(HSIP)2(H2O)18](H2O)5 (H3SIP=5-sulfoi-sophthalic acid), has been synthesized by the hydrothermal reaction of CuCl2 with NaH2SIP at 160 ℃, and characterized by single-crystal X-ray diffraction and IR spectrum. The crystal of the complex crystallizes in a trielinic system, space group P1, with a = 7.0018(5), b = 11.9725(8), c = 19.0424(13) A, α = 78.8540(10), β = 85.1710(10),γ = 83.6080(10)~, V = 1553.24(19) A3, Z = 1, C32H60O51S4Cu5, Mr= 1706.74, Dc= 1.825 g/cm3,μ = 1.937 mm-1, F(000) = 869, the final R = 0.0709 and wR = 0.1503 for 4235 observed reflections with I > 2σ(I). The five Cu2+ ions are connected by two symmetry-related tridentate SIP3- ligands and charge-balanced by two monodentate HSIP2- ligands, giving a discrete pentanuclear structure. The pentanuclear copper molecules are linked by hydrogen bonds to form a three-dimensional supramolecular structure. The temperature-dependent magnetic susceptibility data revealed weak ferromagnetic magnetic interactions between the Cu2+ ions.     

Synthesis,Structure and Luminescent Property of a New Cd(Ⅱ) Complex Containing 2-Propyl-imidazole-4,5-dicarboxylate

A new Cd(Ⅱ) complex([Cd(H2PIDC)2]n) with singly deprotonated 2-propyl-imidazole-4,5-dicarboxylate as bridging ligand was synthesized and characterized by X-ray diffraction method.Crystal data:monoclinic,space group P21/c,with a=8.2547(11),b=10.7071(15),c=13.9131(14),β=126.164(5)o,V=992.8(2)3,C16H18N4O8Cd,Mr=506.74,Z=2,Dc=1.695g/cm3,F(000)=508,μ=1.151 mm-1,R=0.0296 and wR=0.0812 for 1581 observed reflections.Singly deprotonated ligands(H2PIDC-) act as μ3-bridge and join the Cd(Ⅱ) atoms into a 2-D layer structure.The 2-D layers are further linked by intermolecular hydrogen bonds into a 3D network.The luminescent property of the complex was also investigated.     

Hydrothermal Synthesis and Crystal Structure of a Cobalt(Ⅱ) Coordination Polymer: [Co(C2O4)(bix)]n (bix=1,4-Bis(imidazol-1-ylmethyl)-benzene)

<正>A new two-dimensional cobalt coordination polymer has been prepared and fully characterized by elemental analysis, IR, TG and single-crystal X-ray diffraction. The compound [Co(C_2O_4)(bix)]_n 1 crystallizes in the monoclinic system, space group C2/c, with a = 11.549(3), b = 15.700(3), c = 9.260(2), β = 102.984(3)°, V = 1636.0(6)~3, C_(16)H_(14)CoN_4O_4, M_r = 383.23, D_c = 1.556 g/cm~3, μ(MoKα) = 1.078 mm~(-1), F(000) = 780, Z = 4, the final R = 0.0455 and wR = 0.1286 for 1483 observed reflections (I > 2σ(I)). Of the compound, the Co center is octahedrally coordinated with oxalate acting as a tetra-dentate ligand coordinated to the cobalt atom and each bix serving as a bridging ligand by employing two N-donors to coordinate with the Co center. An infinite {Co_2(C_2O_4)_2}_∞ chain is formed along the a axis. Furthermore, the 1D chains are held together via bix ligands to generate a two-dimensional network structure with 1D coronal-like channels (ca. 5.691 × 15.700).     

Supramolecular Terbium-SIP Complex Pillared by 4,4'-Bipyridyl,{[Tb(SIP)(H_2O)_5]_2(bpy)_3(H_2O)}n:Synthesis,Crystal Structure and Photoluminescence

The supramolecular terbium complex, {[Tb(SIP)(H2O)5]2(bpy)3(H2O)}n (NaH2SIP= 5-sulfoisophthalic acid monosodium salt and bpy=4,4'-bipyridyl), has been synthesized by the hydrothermal reaction of Tb4O7 with NaH2SIP and bpy at 165 ℃, and characterized by single-crystal X-ray diffraction, elemental analysis, IR spectrum, powder X-ray diffraction and photoluminescence spectrum. It crystallizes in a monoclinic system, space group C2/c, with a= 30.6840(1), b=10.9206(2), c=17.4967(3), β=111.931(1)o, V=5438.65(14)3, Z=4, C46H52N6O25S2Tb2, Mr=1470.90, Dc=1.796 g/cm3, μ=2.747 mm-1, F(000)=2928, the final R= 0.0654 and wR=0.1322 for 3806 observed reflections with I > 2σ(I). In the neutral [Tb(SIP)(H2O)5]2 motif, the Tb(III) ions are linked by the SIP ligands to form a one-dimensional zigzag chain propagating along the c axis. The zigzag chains are linked together by hydrogen bonds and π-π stacking interactions to form a two-dimensional supramolecular framework. The uncoordinated bpy molecules act as pillars to extend the two-dimensional sheets into a distinctive pillared three-dimensional supramolecular structure through O-H···N hydrogen bonds. The photoluminescence of the complex was investigated at room temperature in the solid state.     

Synthesis, characterization, crystal structure and antitumor activities of a novel demethylcantharidato bridged copper(II) phenanthroline complex

A new polymeric demethylcantharidato (DCA) bridged copper(Ⅱ) phenanthroline (phen) complex ([Cu(DCA)(phen)] n ·nH2O) has been synthesized and characterized by elemental analysis, IR and electronic spectra studies, molar conductivity measurement, and single crystal X-ray diffraction. The complex crystallizes in the orthorhombic space group Pbca with crystallographic data: a = 12.4537(4), b = 9.3897(5), c = 30.1264(10), and Z = 8. In the crystal structure, the octahedral coordinated copper(Ⅱ) ions are bridged by demethylcantharidate ligands into a one-dimensional zigzag-like structure with the Cu···Cu separation of 6.1719, along with phen ligands attached to both sides of the chain alternatively. Interdigitation of the chelating phen ligands of two neighboring chains via hydrophobic interaction and van der Waals forces along ac plane forms two-dimensional polymeric bilayers with discrete water sandwich layer between the adjacent polymeric bilayers. The evaluation of the cytotoxic activity of the copper(Ⅱ) complex against HCT-8 (colorectal carcinoma), A549 (pulmonary carcinoma), HeLa (cervical cancer), HepG2 (hepatocarcinoma), BGC-823 (gastric carcinoma), and MCF-7 (breast adenocarcinoma) cell lines revealed that it is a potent cytotoxic agent, superior to Na2DCA and phen against HeLa, HepG2 and BGC-823 cells.