Investigation of Aconite alkaloids

Summary The composition of the alkaloids in plants of the genus Aconitum —A. kirinense,A. altaicum, A. coreanum, andA. nemorosum — has been studied. Four new alkaloids of composition C₂₆H₄₁O₈N·HNO₃, C₃₅H₄₁O₁₀N·HBr, C₂₀H₂₅O₃N, and C₂₃H₂₉O₆N have been isolated.Khimiya Prirodnykh Soedinenii, Vol. 1, No. 2, pp. 113–116, 1965.     

A chemical study ofPlectranthus glaucocalyx Maxim.

Summary A previously unknown crystalline substance C₂₀H₂₈O₄, calledplectrin, has been isolated from the leaves ofPlectranthus glaucocalyx Maxim., family Labiatae.Khimiya Prirodnykh Soedinenii, Vol. 1, No. 6, pp. 427–428, 1965     

The neutral substances of the oleoresin ofAbies sibirica

Summary The high-boiling neutral fraction of the oleoresin ofAbies sibirica Ldb. contains abientol C₂₀H₃₄O, abietinal C₂₀H₃₀O, abietinol C₂₀H₃₂O, a polymer (C₂₀H₃₄O)₄, and two previously unknown compounds: a diterpene alcohol C₂₀H₃₄O, which we have called isoabienol, and a hydroxyketone C₁₈H₃₀O₂. Structure (I) has been proposed for isolabienol.Khimiya Prirodnykh Soedinenii, Vol. 2, No. 2, pp. 99–104, 1966     

An isomer of coronopilin

Conclusions From the racemes ofC. xanthifolia Fresen. have been isolated a sesquiterpene lactone C₁₆H₂₀O₄, the structural (+)-isomer of (–)-coronopilin, which has not been studied previously; structure I has been proposed for it.Khimiya Prirodnykh Soedinenii, Vol. 5, No. 5, pp. 375–377, 1969     

Feropodin-a sesquiterpene lactone from the roots ofFerula oopoda

Conclusions From the resin of the roots ofFerula oopoda (Boiss. et Buhse) Boiss. a new sesquiterpene lactone, feropodin, with the composition C₁₅H₂₀O₂, mp 140–141° C, has been isolated. The alternative hypothetical structures I and II have been proposed for feropodin.Khimiya Prirodnykh Soedinenii, Vol. 5, No. 4, pp. 245–247, 1969     

A sesquiterpene lactone badkhysinin from the roots ofFerula oopoda

Summary A sesquiterpene lactone with the composition C₂₀H₂₄O₅, mp 104°–105° C, []_D –212.4° C (alcohol) has been isolated from the roots ofFerula oopoda Boiss. and has been called badkhysinin. Badkhysinin is an ester of angelic acid and an epoxyhydroxylactone C₁₅H₁₈O₄ with mp 185°–186° C apparently related to guaianolide with a hydrocarbon skeleton of irregular structure. A number of possible structural formulas for badkhysinin are given.Khimiya Prirodnykh Soedinenii, Vol. 2, No. 2, pp. 93–99, 1966     

Sesquiterpenes of the roots of Inula grandis

Summary The roots ofInula grandis Schrenk has yielded a sesquiterpene lactone C₁₅H₂₀O₃, mp 134–135°C and 270°C, which has been called igalin, and two diols — C₁₅H₂₆O₂ with mp 102–102.5°C and C₁₅H₂₈O₅ with mp 320°C — which have been called igalol and grandol, respectively.Igalol is identical with the diol obtained by the reduction of igalan with sodium borohydride, and has the structure elemane-8,12-diol.The sesquiterpene hydroxy lactone lactone No. 8 has been isolated in the form of an oil and it is now being studied.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 17–20, January, 1971.     

Structure and configuration of a new diterpenoid lactone fromLagochilus hirsutissimus

The epigeal part of the plantLagochilus hirsutissimus has yielded a new diterpenoid lactone — lagohirsidin, C₂₂H₃₄O₅, mp 144–145°C, [] _D ²² – 17.5° (c 1; ethanol). Reduction with LiAlH₄ has yielded a diol C₂₂H₃₈O₅, mp 165–166°C [] _D ²⁰ –1.2 (c 0.6; ethanol). Acid hydrolysis of the diol has led to the formation of lagochilin, C₂₀H₃₆O₅, mp 167–168°C, [] _D ²⁰ –3.9° (c 1; ethanol). The synthesis of lagohirsidin from lagochilin has been effected.V. I. Lenin Tashkent State University. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 788–792, November–December, 1979.     

General characteristics of the polysaccharides of brown algae

Summary From an acetonic extract of the roots ofFerula samarcandica Kor. have been isolated farnesiferol A, gummosin, and two new coumarin substances, samarcandin C₂₄H_30–32O₅ and samarcandone C₂₄H_28–30O₅. Samarcandin has been converted into samarcandone and their probable structures-I and II-have been established.Khimiya Prirodnykh Soedinenii, Vol. 4, No. 2, pp. 73–77, 1968     

Natural quinones

Summary A new anthraquinone of composition C₁₇H₁₄O₅, mp 182–183° (decomp., from benzene) has been isolated from the roots ofRubia iberica (Fisch. ex D.C.); it has been called ibericin and has the structure of 1, 3-dihydroxy-4-ethoxy-methylanthraquinone.Khimiya Prirodnykh Soedinenii, Vol. 2, No. 1, pp. 12–15, 1966     

Polyphenols and acids of Ulugbekia tschimganica

From the herbage ofUlugbekia tschimganica (B. Fedtsch.) Zak two new phenolcarboxylic acids have been isolated in the form of their methyl derivatives: methyl ulugbekate C₁₉H₁₈O₆ (I) and methyl ulugbinate acid C₂₀H₂₂O₇ (II), mp 228°C. It has been established that (I) most probably has the structure of 1,5-bis(3′,4′-dihydroxyphenyl)-3-methoxycarbonylpent-1-ene and (II) that of 1,5-bis(2′,4′-dihydroxyphenyl)-3-methoxycarbonylpent-1-ene and (II) that of 1,5-bis(2′,4′-dihydroxyphenyl)-3-methoxycarbonyl-4-methoxypent-2-ene.     

Structure of isobadkhysin. The stereochemistry of badkhysin and isobadkhysin

Conclusions 1. By chromatography of the total lactones obtained from the sodium carbonate treatment of the resin of the roots ofFerula oopoda (Boiss. et Buhse) Boiss. we isolated a previously unstudied sesquiterpene lactone C₂₀H₂₄O₅, mp 189–190° C, which we called isobadkhysin.2. It has been shown that isobadkhysin is a stereoisomer of badkhysin and is formed during the treatment of the resin with sodium carbonate.3. The stereochemical characteristics of badkhysin and isobadkhysin have been established on the basis of their NMR spectra.Khimiya Prirodnykh Soedinenii, Vol. 6, No. 4, pp. 425–428, 1970     

The isocoumarin artemidinal from Artemisia dracunculus

Summary Artemidinal, C₁₀H₆O₃, which is isocoumarin with an aldehyde group at C₃, has been isolated from the epigeal part ofArtemisia dracunculus.Order of the Red Banner of Labor Institute of the Chemistry of Plant Substances of the Academy of Sciences of the Uzbek SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 257–259, May–June, 1971.     

A study of the alkaloids ofSaussurea salsa andS. elegans

Conclusions 1. In the extraction ofS. salsa andS. elegans, the condensation of the neutral substances with ammonia takes place with the formation of products of a basic nature.2. FromS. elegans a new alkaloid elegantine C₂₃H₂₉O₅N has been obtained the saponification of which has given tyramine and a sesquiterpene lactone.Khimiya Prirodnykh Soedinenii, Vol. 4, No. 6, pp. 367–370, 1968     

A study of the alkaloids of plants of the genusStephania

Summary Four alkaloids have been isolated from the tubers ofStephania glabra (Roxb.) Miers. (synonymSt. rotunda Lour.) collected in the Democratic Republic of Vietnam:l-tetrahydropalmatine and three previously undescribed bases (A -C₁₉H₁₈O₂N, C - C₂₀H₂₅O₄N, and D -C₂₁H₂₅O₄N).Khimiya Prirodnykh Soedinenii, Vol. 1, No. 6, pp. 392–394, 1965.The substances in this paper are denoted by letters. The novelty of these substances has not been established, which contradicts the rules of this journal. The paper is printed as an exception (Editiorial Board).     

Sesquiterpene lactones from Artemisia caucasica

Conclusions 1. Two sesquiterpene lactones have been isolated from the epigeal green part ofArtemisia caucasica Willd.: one with the composition C₁₅H₁₈O₅·H₂O, which has been called grossmisin, and one with the composition C₁₅H₁₈O₅, identified as rutifolin. Structure (I) has been proposed for grossmisin.2. The structure of anhydroaustricin has been reviewed. Structure (II) is proposed for it.Pyatigorsk Pharmaceutical Institute. All-Union Scientific-Research Institute for Medicinal Plants. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 741–744, November–December, 1971.     

The structures of chimganin and chimgin

Summary The roots ofFerula tschimganica Lipsky have yielded two new compounds with the compositions C₁₈H₂₄O₄ (mp 85°C) and C₁₇H₂₂O₃ (mp 155°C), which have been calledchimganin andchimgin. On the basis of their UV, IR, and NMR spectra and the products of alkaline hydrolysis, it has been shown that chimganin is the ester of 4-hydroxy-3-methoxybenzoic acid and chimgin that of 4-hydroxybenzoic acid with (+)-borneol.Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 59–63, January–February, 1972.