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1.
Stereoselective Synthesis of cis-1, 2-cyclopropane Derivatives 总被引:2,自引:0,他引:2
IntroductionNumeroussyntheticmethodsofcyclopropanationhavebeenstudied[l1,butmostofthemarenon-stereoselective,oritsproductisthethermodynamicallystableonewithl,2-transconfiguration.Thestereoselectivesynthesesof1,2-cisisomersofcyclopropanederivativesareseldomseeninliterature.Hereinastere-oselectivecycloporpanationviathereactionofarsenicylidewithe1ectrondefi-cientalkenesisreportedinthispaper.ResultsandDiscussionCarbomethoxymethylenetriphenylarl,oritsarsoniumbromideinthepresenceofK,CO,reactswith2… 相似文献
2.
Hai Ying ZHAO* Zhan Xi BIAN Bao Guo LI College of Chemistry Chemical Engineering Inner Mongolia University Huhhot 《中国化学快报》2004,15(11)
2-Aminoalcohols are useful intermediates in organic chemistry, for example, they serve for the synthesis of various heterocycles1, chelate complexes2, and for the ring expansion of cycloalkanones3. 2-Aminoalcohols containing ferrocene as bidentate ligand may be converted into multinuclear compounds. Several methods for the preparation of 2-aminoalcohols have been developed including reduction of the trimethylsilyl cyanohydrins4 or β-nitromethyl alcohols5 and treatment of the epoxides with a… 相似文献
3.
HaiYingZHAO ZhanXiBIAN BaoGuoLI 《中国化学快报》2004,15(11):1276-1278
2-Amino-l,l-diferrocenylethanol 2 was prepared by reduction of trimethylsilylcyanohydrin ether of diferrocenyl ketone. The crystal structure of 2 was further defined by X-raydiffraction. 相似文献
4.
JinXianWANG XiaoNingSHI KeHuWANG XiuQinMEN 《中国化学快报》2004,15(3):284-285
An efficient and convenient synthesis of 3, 5, 7-triaryl-4H-1, 2-diazepine from 2, 4,6-triarylpyrylium salts and hydrazine in water under microwave irradiation is reported. The same reaction can be conducted using 2, 4, 6-triarylthiopyrylium salts and hydrazine. 相似文献
5.
Synthesis of 2-Arylimidazo[1, 2-a]pyrimidines in Ionic Liquids 总被引:1,自引:0,他引:1
DanQianXU BaoYouLIU ZhenYuanXU 《中国化学快报》2003,14(10):1002-1004
Room temperature ionic liquids were used as a “green“ recyclable alternative to conventional solvents in the synthesis of pharmaceutically useful compounds 2-arylimidazo[1, 2-a]pyrimidines through Tschotschibabin reaction of a-bromoacetophenones with 2-aminopyrimidine in good yields. 相似文献
6.
4-Trifluoromethyl-1,2-dihydropyrimidines were synthesized in moderate yields by the one-pot reaction of 4-ethoxy-1,1,1-trifluoro-3-buten-2-one, aldehydes and ammonia catalyzed by zinc chloride under mild conditions. 相似文献
7.
Lian You ZHENG Xu BAI 《中国化学快报》2006,17(2):165-168
Nucleophilic addition of organometallics to imines or iminium ion has received greatattention in recent years, especially in the field of asymmetric synthesis1. Addition ofthe nucleophilic reagents to quinoxalines was proved to be a useful method for thes… 相似文献
8.
Wei Ming XU Lu Ling WU Xian HUANG 《中国化学快报》2006,17(5):603-605
The preparation of diverse libraries of organic compounds is an important facet of modern drug discovery programs. One of the most commonly employed method in library production is solid phase organic synthesis (SPOS)1. Experience has shown that the compo… 相似文献
9.
Jia Rong LI Shu Ling MA 《中国化学快报》2005,16(11):1424-1426
2H-3, 1-Benzoxazine heterocyclic compounds are a series of potent nonsteroidal pro- gesterone receptor agonists1-3 and have many other applications such as carbonaceous electrode, plant growth regulating and anti-stress activities4-6, etc.. Comparing to other benzoxazine series, such as 1, 4-benzoxazine, 2H-1, 3-benzoxazine, etc., little attentions have been paid for this series of compounds. There is only one method for the preparation of 2H-3, 1-benzoxazine, e.g. cyclocondensation of o-amin… 相似文献
10.
11.
Wei LIU Yuan MA Ying Wu YIN Yu Fen ZHAO 《中国化学快报》2006,17(6):736-738
Anodic cyanation is expected to provide a promising method for synthesis of nitriles by reason of its positional reactivity and simple operation1. Within our ongoing interest in cyano group incorporation into small heterocyclic ring systems2, 3, the elect… 相似文献
12.
The synthesis and characterization of extended, conjugated molecules containing isoindolinone units was explored. Nucleophilic cyclizations between an amide and an alkyne were found to be an efficient method of producing the desired isoindolin-1-ones in high yields. A variety of derivatives were synthesized, demonstrating that a number of structural alterations could be made while maintaining good regio- and stereospecificity in the cyclized product. 相似文献
13.
1 INTRODUCTIONDithioacetals[1 3]havedemonstratedtheirpotentialforthesynthesisofheterocy cles,therefore ,theirsynthesisandreactionshaveattractedmuchattention ,butverylittlehasbeenreportedabouttheoxidationofdithioacetals[4].Accordingtotheprevi ousreport,theoxid… 相似文献
14.
Xu Dong LIU Meng Xian DING Lian Xun GAO* State Key Laboratory of Polymer Physics Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 《中国化学快报》2004,15(1)
Polymer-supported reagents and catalysts have attracted considerable attention as they offer alternative methods to separate and reuse expensive and often toxic chemicals1. Traditionally, the polymer-supported chiral catalysts are prepared by anchoring highly enantioselective monomeric catalysts to flexible and sterically irregular polymer supports. Because of the stereo-irregularity and flexibility of the traditional polymeric chiral catalysts, their catalytic sites do not have well-defined… 相似文献
15.
Synthesis of 3-Phenyl-6-formyl-3, 4-dihydro-2H-1, 3-benzoxazine 总被引:2,自引:0,他引:2
Qi Chao RAN Qiao TIAN Yi GU 《中国化学快报》2006,17(10):1305-1308
Benzoxazine is a novel class of thermosetting resins, which possesses lots of outstanding properties such as no by-products and near-zero shrinkage during polymerization as well as good molecular design flexibility1-2. Furthermore, polybenzoxazines (PBZs)… 相似文献
16.
JianGuoYANG XinYuYU HaiHongWU ZhiLinCHENG YueMingLIU MingYuanHE 《中国化学快报》2005,16(3):299-302
The synthesis of 2, 4, 6-triisopropyl- 1, 3, 5-trioxane with high yield and desirable selectivity from solvent-free cyclotrimerization of isobutyraldehyde catalyzed by ionic liquids was reported in this work. 相似文献
17.
Abstract The title 1, 2-anhydro sugar (10) was synthesized from methyl 4, 6-O-benzylidene-α-D-glucopyranoside or from 1, 2-O-ethylidene-α-D-glucopyranose. The key intermediate for the synthesis was 2-O-acetyl-3, 4-di-O-benzyl-6-deoxy-β-D-glucopyranosyl fluoride (8)which was transformed into the target compound by ring closure with potassium tert-butoxide. Calculations by the modified Karplus equation from vicinal coupling constants of 10 suggested that the conformation of 10 was almost an ideal 4 H 5 for the pyranose ring. Conformational analysis for the 1, 2-O-(R)-ethylidene intermediates 17 and 20 revealed that their pyranose ring basically adopted a B2,5 conformation. 相似文献
18.
A series of novel dinuclear platinum(Ⅱ) complexes with (1S, 3S)-1,2,3,4-tetrahydroisoquinolines as the ligands were synthesized as potential anticancer agents in several steps starting from commercially available L-DOPA. The cytotoxicities of the series of dinuclear platinum(Ⅱ) complexes of tetrahydroisoquinoline were tested against HCT-8, BEL-7402, A2780, MCF-7, Hela, A549 and BGC-823 cell lines by the MTT test. These complexes showed selective inhibition activity against cisplatin-insensitive cell line Skov3. 相似文献
19.
XU Liang-zhong ZHOU Kai HU Zhi-qiang BI Wen-zhao College of Chemistry Molecular Engineering Qingdao University of Science Technology Qingdao P. R. China 《高等学校化学研究》2006,22(6):765-767
IntroductionAs an important type of fungicide, compoundscontaining 1,2,4-triazole groups have attracted muchattention because they exhibit a certain fungicidal acti-vity againstPuccinia reconditeand also play a role inroot-growth regulation[1—3]. However… 相似文献
20.
De Jiang LI He Qing FU 《中国化学快报》2006,17(5):625-627
1, 3, 4-Oxadiazoline derivatives are found to possess significant biological activities such as antifungal1, insecticidal2, CNS depressant3-5, anticonvulsant effects and plant growth accelerator. They are highly important heterocycles, and have been used … 相似文献