共查询到20条相似文献,搜索用时 31 毫秒
1.
Bożena Modzelewska-Banachiewicz Barbara Michalec Teresa Kamińska Liliana Mazur Anna E. Kozioł Jacek Banachiewicz Marzena Ucherek Martyna Kandefer-Szerszeń 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):439-444
Abstract (Z)-3-(3,4-diaryl-1,2,4-triazole-5-yl)prop-2-enoic acid derivatives were obtained in the course of the reaction of N
3-substituted amidrazones with maleic anhydride, and isomerized into the (E) isomers by heating under reflux in acetic acid solution. The molecular structure of the compounds obtained was confirmed
by IR and 1H NMR spectroscopy, and by X-ray crystallography for (2E)-3-(4,5-diphenyl-4H-1,2,4-triazol-3-yl)prop-2-enoic acid. The antiviral and immunomodulating activity of several of the compounds was examined.
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2.
Abstract One-pot, three-components synthesis of 2,4,6-triarylpyridines and 5-unsubstituted-3,4-dihydropyrimidin-2(1H)-ones was performed under solvent-free conditions using molecular iodine as the catalyst in moderate to good product yields.
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3.
Nagnnath D. Kokare Devanand B. Shinde 《Monatshefte für Chemie / Chemical Monthly》2009,140(2):185-188
Abstract Aromatic aldoximes were converted to the corresponding nitriles in good to excellent yields by employing phosphoric acid diethyl
ester 2-phenylbenzimidazol-1-yl ester as reagent. The method was equally effective for oximes bearing electron-donating and
electron-withdrawing substituents.
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4.
Fangfang Dang Xinwei Wang Guoping Han Yahong Yao 《Monatshefte für Chemie / Chemical Monthly》2009,140(6):615-617
Abstract A 3D metal-organic framework, [C6H3CdN2O4]·NH4, was synthesized solvothermally and structurally characterized by single-crystal X-ray structure determination. This compound
crystallizes in the tetragonal system with the space group P42/nmc. The crystal structure presents a 3D framework and open channels, exhibiting guest-coordination sites at channel walls and
strong fluorescent emission.
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5.
Marko P. Sušnik Michael Schnürch Marko D. Mihovilovic Kurt Mereiter Peter Stanetty 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):423-430
Abstract A short and efficient sequence for the synthesis of a series of 4-(2-amino-5-thiazolyl)-pyrimidine-2-amines was developed.
1-Phenyl-2-(6-pyrimidinyl)-ethanones, obtained via Weinreb’s methodology, were used in a Hantzsch thiazole cyclization reaction,
followed by introduction of the aniline moieties via nucleophilic substitution.
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6.
Abolghasem Davoodnia Mehdi Bakavoli Mehdi Soleimany Niloofar Tavakoli-Hoseini 《Monatshefte für Chemie / Chemical Monthly》2009,47(3):355-358
Abstract A new route to the synthesis of 2-arylthieno[2,3-d]pyrimidin-4(3H)-ones has been developed through heterocyclization of 2-amino-4,5-dimethylthiophene-3-carboxamide
with aromatic aldehydes in boiling glacial acetic acid followed by air oxidation. The unoxidized intermediates, 2-aryl-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones, are isolated when the reactions are carried out either at room temperature or under a nitrogen atmosphere.
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7.
Wael A. El-Sayed Ibrahim F. Nassar Adel A.-H. Abdel-Rahman 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):365-370
Abstract New C-furyl glycosides bearing pyrazolines, isoxazolines, and dihydropyrimidine-2(1H)-thiones were synthesized in order to increase the number of tested compounds screened for antimicrobial activity. The antimicrobial
activity screening showed that the pyrazoline derivatives were the most active compounds.
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8.
Farhad Shirini Mohammad Ali Zolfigol Masoumeh Abedini 《Monatshefte für Chemie / Chemical Monthly》2009,140(1):61-64
Abstract Saccharin sulfonic acid was easily prepared by the reaction of saccharin with neat chlorosulfonic acid at room temperature.
This reagent is efficiently able to catalyze the chemoselective trimethylsilylation of alcohols with hexamethyldisilazane
in the presence of amines and thiols.
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9.
Bakr F. Abdel-Wahab Hatem A. Abdel-Aziz Essam M. Ahmed 《Monatshefte für Chemie / Chemical Monthly》2009,140(6):601-605
Abstract Potassium hydrazinecarbodithioate were prepared by treatment of acid hydrazides with carbon disulfide in the presence of potassium
hydroxide. Reaction of this potassium salt with hydrazine hydrate, phenacyl bromide, or hydrazonoyl chlorides afforded 1,2,4-triazole,
1,3-thiazole, and 1,3,4-thiadiazoles. Reaction of 1,2,4-triazole with phenacyl bromide or hydrazonoyl chlorides afforded the
corresponding 1,2,4-triazolo[3,4-b][1, 3, 4]-thiadiazines. All these new compounds were screened for antibacterial and antifungal activity. Some had promising
activity.
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10.
Mohammad A. Khalilzadeh Issa Yavari Zinatossadat Hossaini Hasan Sadeghifar 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):467-471
Abstract A novel method for oxazine ring formation is established using the reaction of ammonium thiocyanate and acid chlorides with
napthols in the presence of N-methylimidazole to afford [1,3]oxazine-4-thione derivatives in excellent yields.
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11.
Vera L. M. Silva Artur M. S. Silva Diana C. G. A. Pinto José A. S. Cavaleiro José Elguero 《Monatshefte für Chemie / Chemical Monthly》2009,140(1):87-95
Abstract An efficient synthesis method for the preparation of a series of new (Z)- and (E)-3(5)-(2-hydroxyphenyl)-4-styrylpyrazoles was developed. The reaction of (Z)- and (E)-3-styrylchromones with hydrazine hydrate afforded the corresponding (Z)- and (E)-3(5)-(2-hydroxyphenyl)-4-styrylpyrazoles, except for nitro derivatives, where both (Z)- and (E)-4′-nitro-3-styrylchromones afforded (E)-3(5)-(2-hydroxyphenyl)-4-(4-nitrostyryl)pyrazoles. The reaction mechanism for these transformations is discussed and the
stereochemistries of all products were established by NMR experiments.
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12.
Jian-Feng Zhou Gui-Xia Gong Kun-Bo Shi Yu-Lan Zhu 《Monatshefte für Chemie / Chemical Monthly》2009,140(6):651-654
Abstract A facile procedure for the synthesis of quinoxalines is being reported starting from 3-(2-bromoacetyl)coumarins or 3-(2-bromobutanoyl)coumarins
and substituted o-phenylenediamines. The reactions were carried out under catalyst-free and microwave irradiation conditions producing the
title compounds in moderate to excellent yields in a short time with easy workup. The structures of all new compounds have
been confirmed on the basis of their IR, 1H NMR, 13C NMR, and HRMS data.
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13.
Abstract A classical convergent approach for the synthesis of the anticancer drug imatinib has been substantially improved. Imatinib
was assembled by coupling the amine and carboxylic acid precursors by using N,N′-carbonyldiimidazole (CDI) as a condensing agent. Both intermediates have been synthesized by novel efficient methods.
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14.
Mohamed A. A. Radwan Marwa A. Shehab Siham M. El-Shenawy 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):445-450
Abstract 5-Aminobenzo[b]thiophene-2-carboxylic acid was converted to the corresponding 5-(2-chloroacetamido)benzo[b]thiophene-2-carboxylic acid by reaction with chloroacetyl chloride. This acetamido product was treated with different alkyl,
cycloalkyl, aryl, and heterocyclic amines to afford a series of C5-substituted benzo[b]thiophenes. These compounds were found to possess potent anti-inflammatory activity.
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15.
Min Wang Zhi-Guo Song Hong Gong Heng Jiang 《Monatshefte für Chemie / Chemical Monthly》2009,140(2):177-179
Abstract Tetrahydropyranylation of alcohols and phenols was accomplished successfully using copper nitrate and acetic acid as a synergistic
catalyst at room temperature under solvent-free condition. Compared with other synergistic catalytic systems, copper nitrate/acetic
acid proved to be the most efficient. Both alcohols (primary, secondary, tertiary, benzylic, cyclic, allyl, cinnamyl, and
furyl) and phenols reacted smoothly in high yields.
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16.
Barahman Movassagh Mohammad Soleiman-Beigi 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):409-411
Abstract A simple, highly efficient, and green protocol has been developed for preparation of sulfides from alkyl or aryl thiols and
benzyl-, allyl-, t-butyl, and adamantyl halides under solvent- and catalyst-free conditions.
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17.
Maram R. Al-Dweik Jalal A. Zahra Monther A. Khanfar Mustafa M. El-Abadelah Klaus-Peter Zeller Wolfgang Voelter 《Monatshefte für Chemie / Chemical Monthly》2009,140(2):221-228
Abstract A series of ethyl 2-(substituted)-9-cyclopropyl-4-fluoro-6-oxo-1H-imidazo[4,5-h]quinoline-7-carboxylates has been prepared from ethyl 7,8-diamino-1,4-dihydroquinoline-3-carboxylate via thermally induced
reactions with model alkanoic acids or via microwave-assisted cyclocondensation with some arene carboxaldehydes. Acid-catalysed
hydrolysis of the resulting ester derivatives furnished the corresponding imidazoquinoline-7-carboxylic acids. The structures
of these new acid and ester derivatives are based on microanalytical and spectral (IR, MS, and NMR) data.
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18.
Do-Min Lee Gullapalli Kumaraswamy Kee-In Lee 《Monatshefte für Chemie / Chemical Monthly》2009,140(1):73-78
Abstract Catalytic transfer hydrogenation of α-tosyloxyarylketones mediated by a chiral rhodium complex using an azeotropic mixture
of formic acid/triethylamine afforded the corresponding 1-arylethanediol monotosylates in excellent yield with high enantioselectivity.
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19.
Marco Rupprich Clemens Decristoforo Barbara Matuszczak 《Monatshefte für Chemie / Chemical Monthly》2009,140(4):405-407
Abstract In contrast to the results presented in a previous report, the direct conversion of alcohols to alkyl fluorides with triphenylphosphine
and potassium fluoride in CCl4/DMF under mild conditions failed.
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20.
Karen S. M. Corrêa Marcio C. S. de Mattos Mônica R. M. P. de Aguiar 《Monatshefte für Chemie / Chemical Monthly》2009,140(5):519-522
Abstract Styrene oxide is easily prepared in 82–91% yield by the reaction of styrene with iodine/water in the presence of commercial
clays, followed by in situ addition of KOH in n-hexane/water.
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