共查询到20条相似文献,搜索用时 31 毫秒
1.
Micromotor endoscope catheter for in vivo, ultrahigh-resolution optical coherence tomography 总被引:5,自引:0,他引:5
Herz PR Chen Y Aguirre AD Schneider K Hsiung P Fujimoto JG Madden K Schmitt J Goodnow J Petersen C 《Optics letters》2004,29(19):2261-2263
A distally actuated, rotational-scanning micromotor endoscope catheter probe is demonstrated for ultrahigh-resolution in vivo endoscopic optical coherence tomography (OCT) imaging. The probe permits focus adjustment for visualization of tissue morphology at varying depths with improved transverse resolution compared with standard OCT imaging probes. The distal actuation avoids nonuniform scanning motion artifacts that are present with other probe designs and can permit a wider range of imaging speeds. Ultrahigh-resolution endoscopic imaging is demonstrated in a rabbit with <4-microm axial resolution by use of a femtosecond Cr:forsterite laser light source. The micromotor endoscope catheter probe promises to improve OCT imaging performance in future endoscopic imaging applications. 相似文献
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Choi D Hiro-Oka H Furukawa H Yoshimura R Nakanishi M Shimizu K Ohbayashi K 《Optics letters》2008,33(12):1318-1320
We describe high-speed Fourier domain optical coherence tomography (OCT) using optical demultiplexers (ODs) for spectral dispersion. The OD enables separation of a narrow spectral band of 14 GHz (0.11 nm) from a broadband incident light at 256 different frequencies in 25.0 GHz intervals centered at 192.2 THz (1559.8 nm). OCT imaging of 60,000,000 axial scans per second was achieved through parallel signal acquisition using 256 balanced photoreceivers to simultaneously detect all the output signals from the ODs in a Fourier domain OCT system. OCT imaging at a 16 kHz frame rate, 1100 A-lines per frame, 3 mm depth range, and 23 microm resolution was demonstrated using a resonant scanner for lateral scanning. 相似文献
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Munce NR Mariampillai A Standish BA Pop M Anderson KJ Liu GY Luk T Courtney BK Wright GA Vitkin IA Yang VX 《Optics letters》2008,33(7):657-659
A novel flexible scanning optical probe is constructed with a finely etched optical fiber strung through a platinum coil in the lumen of a dissipative polymer. The packaged probe is 2.2 mm in diameter with a rigid length of 6mm when using a ball lens or 12 mm when scanning the fiber proximal to a gradient-index (GRIN) lens. Driven by constant high voltage (1-3 kV) at low current (< 5 microA), the probe oscillates to provide wide forward-viewing angle (13 degrees and 33 degrees with ball and GRIN lens designs, respectively) and high-frame-rate (10-140 fps) operation. Motion of the probe tip is observed with a high-speed camera and compared with theory. Optical coherence tomography (OCT) imaging with the probe is demonstrated with a wavelength-swept source laser. Images of an IR card as well as in vivo Doppler OCT images of a tadpole heart are presented. This optomechanical design offers a simple, inexpensive method to obtain a high-frame-rate forward-viewing scanning probe. 相似文献
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A fiber-optic-bundle-based optical coherence tomography (OCT) probe method is presented. The experimental results demonstrate this multimode optical fiber-bundle-based OCT system can achieve a lateral resolution of 12 microm and an axial resolution of 10 microm with a superluminescent diode source. This novel OCT imaging approach eliminates any moving parts in the probe and has a primary advantage for use in extremely compact and safe OCT endoscopes for imaging internal organs and great potential to be combined with confocal endoscopic microscopy. 相似文献
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水下气泡高速摄影光学系统设计 总被引:2,自引:0,他引:2
为了研究水下气泡的粒径、速度和浓度特性,提出基于高速电荷耦合器件(CCD)的气泡照明和三维摄影光学系统.采用532nm半导体激光器,基于伽利略结构用三个柱面镜设计了厚度1.5mm,宽度44mm的片光源。设计物像距530mm,放大率为0.4,1,2.5倍(×)的摄影光学系统,每组均由共用前组镜和会聚镜组成,中间以平行光中继。通过同步移动片光源和共用前组镜实现60mm×40mm视场内二维高速成像和纵向5mm扫描,具有结构简单、性能可靠的特点。对设计结果进行评价,0.4,1,2.5×成像光学系统在0.707ω,50lp/mm时调制传递函数值分别为0.58,0.55和0.38,能够分辨粒径范围为10~450μm的气泡。 相似文献
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适合于内窥成像的共路型光学相干层析成像系统 总被引:4,自引:1,他引:3
提出了一种采用光纤型迈克耳孙干涉仪进行光程补偿的菲佐型光学相干层析成像(OCT)系统.该系统的传感探头为共路干涉结构,以解决现有内窥光学相干层析成像系统中存在的探头运动导致图像失真、以及更换使用不同探头时需进行色散和偏振态调节等问题.光程补偿和振动干扰实验结果表明,光程补偿方法正确可行,系统对环境干扰不敏感.利用研制的系统对反射镜和近红外卡进行了成像实验,验证了系统的有效性.提出的方法非常适合于内窥成像,并给出了把系统扩展为内窥光学相干层析成像系统的具体实现过程. 相似文献
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An endoscopic optical coherence tomography (OCT) system based on a microelectromechanical mirror to facilitate lateral light scanning is described. The front-view OCT scope, adapted to the instrument channel of a commercial endoscopic sheath, allows real-time cross-sectional imaging of living biological tissue via direct endoscopic visual guidance. The transverse and axial resolutions of the OCT scope are roughly 20 and 10.2mum, respectively. Cross-sectional images of 500x1000 pixels covering an area of 2.9 mmx2.8 mm can be acquired at ~5 frames/s and with nearly 100-dB dynamic range. Applications in thickness measurement and bladder tissue imaging are demonstrated. 相似文献
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微型数字式太阳敏感器光学系统由APS CMOS图像传感器和基于MEMS工艺的小孔阵列式光线引入器组成。图像传感器的分辨率为1024×1024pixel,像素尺寸为10μm×10μm;光线引入器具有微小孔阵列结构,小孔为方形孔,30×30阵列,尺寸为60μm×60μm,间距为250μm。光线引入器采用了MEMS工艺的掩模板制备工艺。针对所设计的光学系统计算了曝光时间,并在此基础上进行了地面成像实验。实验结果表明,光学系统设计合理,保证了敏感器所具有的高精度和大视场。 相似文献
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Intraluminal fiber-optic Doppler imaging catheter for structural and functional optical coherence tomography 总被引:1,自引:0,他引:1
We describe a miniature fiber-optic Doppler imaging catheter for integrated functional and structural optical coherence tomography (OCT) imaging. The Doppler catheter can map blood flow within a vessel as well as image vessel wall structures. A prototype Doppler catheter has been developed and demonstrated for measuring the intraluminal velocity profile in a vessel phantom (conduit). A simple mathematical model is demonstrated to estimate the total flow rate. This estimation technique also enables the spatial range of flow measurements to be extended by approximately two times the normal OCT image-penetration depth. The Doppler OCT catheter could be a powerful device for cardiovascular imaging. 相似文献
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为了实现快速低成本改变光学系统焦距,设计了基于液体透镜的变焦结构光三维成像镜头和微透镜阵列。系统采用7片球面玻璃镜片和1片液体透镜结构, F#为3.2,全视场大小为10 mm,总长180 mm,焦距变化范围54 mm~61 mm。结果表明:该系统能实现投影距离227 mm~256 mm调节,调焦过程中目标表面清晰,细节分辨率高,系统在整个变焦区域内,在40 lp/mm时,全视场MTF优于0.2,系统场曲小于0.2,畸变小于0.2%。柱面微透镜阵列整体尺寸为10 mm×10 mm,周期宽度为1 mm,厚度为1 mm。随着投影距离的增长,光学系统成像质量先上升后下降,在237 mm处成像质量最优,随着投影距离的增加,光学系统的放大倍率增大,光学系统整体相对照度不均匀性小于0.2。 相似文献
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PS(PerfectShuffle)opticalinterconnectioncancomposedvariousopticalinterconnectionnetworks,forexampleΩnetwork.However,itsconver... 相似文献
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A method of N×N sub-array crisscross insertion has been put forward. N×N holographic lens array is used for realizing PS-1 optical interconnection of the 2N×2N element array. The condition for the sub-array interlacing was analyzed. The formula of the PS-1 imaging magnifying power and the imaging distance have been given for both parallel light illumination and divergent light illumination. The results indicated that the formula of the PS-1 imaging magnifying power and imaging distance realized by N×N sub-array crisscross insertion are identical with the results of the PS realized by 2×2 holographic lens array. The experiments prove correctness of the formula. 相似文献
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Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography 总被引:1,自引:0,他引:1
A nonreciprocal fiber-optic interferometer is demonstrated in an optical coherence tomography (OCT) system. The increased power efficiency of this system provides a 4.1-dB advantage over standard Michelson implementations. In addition, a new linear-scanning fiber-optic catheter is demonstrated that avoids the rotary optical junction that is required in circumferential scanning systems. These advancements have permitted the clinical implementation of OCT imaging in the human gastrointestinal tract. 相似文献
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为了同时获取样品的表面和深度信息,研究光学相干层析的成像原理,建立了基于光学相干层析技术的内窥系统,实现了旋转扫描成像,系统的工作波长为1 310 nm,工作带宽为80 nm.理论推导及计算机仿真得到了系统信噪比与干涉仪的分光比、反射率之间的关系并分析了理论分辨率和探测深度.提出外径为5 mm的内窥镜扫描探头,聚焦距离为12 mm,数值孔径NA为0.47,折射率分布常量A=0.218 7.利用微型电机驱动直角棱镜实现扫描,旋转速度为25 rpm,旋转一周得到640个采样点.采用多层盖玻片和洋葱表皮作为样品进行实验分析,得到了盖玻片和洋葱的图像,横向分辨率和纵向分辨率分别为10 μm和15 μm.结果表明,设计的光学相干层析内窥系统能够用于旋转扫描成像,获取更多的组织信息. 相似文献
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Yang VX Mao Y Standish BA Munce NR Chiu S Burnes D Wilson BC Vitkin IA Himmer PA Dickensheets DL 《Optics letters》2006,31(9):1262-1264
An elliptical microelectromechanical system (MEMS) membrane mirror is electrostatically actuated to dynamically adjust the optical beam focus and track the axial scanning of the coherence gate in a Doppler optical coherence tomography (DOCT) system at 8 kHz. The MEMS mirror is designed to maintain a constant numerical aperture of approximately 0.13 and a spot size of approximately 6.7 microm over an imaging depth of 1mm in water, which improves imaging performance in resolving microspheres in gel samples and Doppler shift estimation precision in a flow phantom. The mirror's small size (1.4 mm x 1 mm) will allow integration with endoscopic MEMS-DOCT for in vivo applications. 相似文献
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为了同时获取样品的表面和深度信息,研究光学相干层析的成像原理,建立了基于光学相干层析技术的内窥系统,实现了旋转扫描成像,系统的工作波长为1 310 nm,工作带宽为80 nm.理论推导及计算机仿真得到了系统信噪比与干涉仪的分光比、反射率之间的关系并分析了理论分辨率和探测深度.提出外径为5 mm的内窥镜扫描探头,聚焦距离为12 mm,数值孔径NA为0.47,折射率分布常量A=0.218 7.利用微型电机驱动直角棱镜实现扫描,旋转速度为25 rpm,旋转一周得到640个采样点.采用多层盖玻片和洋葱表皮作为样品进行实验分析,得到了盖玻片和洋葱的图像,横向分辨率和纵向分辨率分别为10 μm和15 μm.结果表明,设计的光学相干层析内窥系统能够用于旋转扫描成像,获取更多的组织信息. 相似文献
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J.B. Eom Y. Kim S.J. Lee E.J. Min S.J. Park B.H. Lee 《Optics Communications》2012,285(21-22):4333-4337
A lensed patch cord probe has been made with a ball lens packaged in a metal cylinder. By simply placing a ball lens directly in front of a fiber patch cord, a compact and potentially disposable sampling probe for optical coherence tomography (OCT) could be implemented. To achieve a sufficiently long working distance and a good transverse resolution simultaneously, the proper ball lens diameter and the distance between the ball lens and the fiber patch cord were investigated. Experimentally, a working distance of up to 5.2 mm, 3 dB bandwidth of 2 mm, and transverse resolution of 16 μm were achieved. With the patch cord probe, a common path swept source OCT system was implemented and used to demonstrate the feasibility as the dedicated probe for dentistry. 相似文献
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光纤型光学相干层析成像系统的研制 总被引:22,自引:7,他引:15
光学相干层析(OCT)成像技术是一新近发展的高分辨力生物医学成像手段,能非侵入性地对活体内部的结构与生理功能进行可视化观察。采用宽带近红外光源,基于迈克耳孙干涉原理和外差探测方法,建立了单模光纤型光学相干层析成像系统,相干地提取从生物体内部返回的深度分辨的弹性散射光信息,并依此构筑了自然状态下活体组织的二维光学相干层析成像图像和三维光学相干层析成像图像。光纤化设计的光学相干层析成像系统紧凑、灵活,便于与光纤导管、内窥镜和其它成像装置的有机结合,以拓展其观察范围和应用领域。 相似文献