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同位素质谱和无机质谱 总被引:2,自引:0,他引:2
本文是《分析试验室》定期评述中“同位素质谱和无机质谱”的第四篇评述,评述的范围是1994年11月至1996年10月我国气体同位素质谱,热电离同位素质谱,加速器质谱,火花源质谱,电感耦合等离子体质谱,辉光放电质谱,同位素稀释质谱,二次离子质谱,激光共振电离子飞行时间质谱,电子探针,质子探针,激光探针和它们在地学,核科学,环境科学,材料学,计理学,医学和生命科学中的应用,引用文献149篇。 相似文献
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本文与本刊1991年专栏评述衔接,评述了1991~1992年10月间我国同位素质谱和无机质谱分析的情况。包括同位素分析、同位素示踪、同位位素稀释、同位素质谱计研制、火花质谱、二次离子质谱、离子探针、等离子体质谱等。资料来源以国内为主,也收集了少量代表学科先进水平的外国文献。参考文献252篇。 相似文献
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N. A. Klyuev 《Journal of Analytical Chemistry》2002,57(6):462-479
The review is devoted to the use of mass spectrometry and chromatography–mass spectrometry in various areas of pharmaceutical chemistry. The role of the above techniques in the structural identification of impurities in drug preparations and in the determination of the biotransformation behavior of pharmaceuticals in human and animal bodies is shown. The inactivation of drugs under the action of external factors (oxidation by atmospheric oxygen and the effects of moisture, heat, and light) is illustrated. The use of various ionization techniques and the spectra of metastable ions for determining the structures of components of biologically active substances are exemplified. 相似文献
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Field desorption (FD) enables mass-spectrometric investigation of large organic molecules without their vaporization. The present state of our theoretical understanding of the ionization of these molecules in the adsorbed state on organic emitters is described. The special problems of the technique and prospective developments in the apparatus for future analytical problems are outlined. The present progress report concentrates on analytical studies of biochemical model compounds and degradation products from environmental chemicals and drugs. The method is particularly suitable for the detection and identification of submicrogram quantities of underivatized polar substances present in complex mixtures or pre-purified extracts from biological materials. 相似文献
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Bamberger C Renz U Bamberger A 《Journal of the American Society for Mass Spectrometry》2011,22(6):1079-1087
Methods to visualize the two-dimensional (2D) distribution of molecules by mass spectrometric imaging evolve rapidly and yield
novel applications in biology, medicine, and material surface sciences. Most mass spectrometric imagers acquire high mass
resolution spectra spot-by-spot and thereby scan the object’s surface. Thus, imaging is slow and image reconstruction remains
cumbersome. Here we describe an imaging mass spectrometer that exploits the true imaging capabilities by ion optical means
for the time of flight mass separation. The mass spectrometer is equipped with the ASIC Timepix chip as an array detector
to acquire the position, mass, and intensity of ions that are imaged by matrix-assisted laser desorption/ionization (MALDI)
directly from the target sample onto the detector. This imaging mass spectrometer has a spatial resolving power at the specimen
of (84 ± 35) μm with a mass resolution of 45 and locates atoms or organic compounds on a surface area up to ~2 cm2. Extended laser spots of ~5 mm2 on structured specimens allows parallel imaging of selected masses. The digital imaging mass spectrometer proves high hit-multiplicity,
straightforward image reconstruction, and potential for high-speed readout at 4 kHz or more. This device demonstrates a simple
way of true image acquisition like a digital photographic camera. The technology may enable a fast analysis of biomolecular
samples in near future. 相似文献
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Temperature-programmed desorption mass spectrometry (TPD MS) is discussed with reference to studies of modified pyrogenic
oxides. Simple theoretical models are presented in order to allow an approximate analytical treatment of TPD MS data. The
formulae for rate constant are presented for first-, second- and third-order reactions. Products of thermal decomposition
of carbonized surface layer are observed and identified. The different pathways of uni- and bimolecular desorption were investigated
by temperature-programmed desorption mass spectrometry. The rate constants of reactions were derived from TPD MS measurements.
Applications of TPD MS to investigation of endocrine disruptors fate and formations on the solid aerosol surface are discussed.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
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Philip Lössl Joost Snijder Albert J. R. Heck 《Journal of the American Society for Mass Spectrometry》2014,25(6):906-917
Over the last two decades, native mass spectrometry (MS) has emerged as a valuable tool to study intact proteins and noncovalent protein complexes. Studied experimental systems range from small-molecule (drug)–protein interactions, to nanomachineries such as the proteasome and ribosome, to even virus assembly. In native MS, ions attain high m/z values, requiring special mass analyzers for their detection. Depending on the particular mass analyzer used, instrumental mass resolution does often decrease at higher m/z but can still be above a couple of thousand at m/z 5000. However, the mass resolving power obtained on charge states of protein complexes in this m/z region is experimentally found to remain well below the inherent instrument resolution of the mass analyzers employed. Here, we inquire into reasons for this discrepancy and ask how native MS would benefit from higher instrumental mass resolution. To answer this question, we discuss advantages and shortcomings of mass analyzers used to study intact biomolecules and biomolecular complexes in their native state, and we review which other factors determine mass resolving power in native MS analyses. Recent examples from the literature are given to illustrate the current status and limitations. Figure
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Pei Su Hang Hu Daisy Unsihuay Di Zhang Dr. Tiziano Dainese Dr. Rosa E. Diaz Jongsu Lee Dr. Don K. Gunaratne Prof. Haiyan Wang Prof. Flavio Maran Prof. Jianguo Mei Prof. Julia Laskin 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2020,132(20):7785-7790
The design of functional interfaces is central to both fundamental and applied research in materials science and energy technology. We introduce a new, broadly applicable technique for the precisely controlled high-throughput preparation of well-defined interfaces containing polyatomic species ranging from small ions to nanocrystals and large protein complexes. The mass-dispersive deposition of ions onto surfaces is achieved using a rotating-wall mass analyzer, a compact device which enables the separation of ions using low voltages and has a theoretically unlimited mass range. We demonstrate an efficient deposition of singly charged Au144(SC4H9)60 ions (33.7 kDa), which opens up exciting opportunities for the structural characterization of nanocrystals and their assemblies using transmission electron microscopy. Our approach also enables the high-throughput deposition of mass-selected ions from multicomponent mixtures, which is of interest to the controlled preparation of surface gradients and rapid screening of molecules in mixtures for a specific property. 相似文献
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食品中胆固醇色谱/质谱/质谱的测定 总被引:3,自引:0,他引:3
确立了用色谱/质谱/质谱测定食品中胆固醇的一种新方法,试样经乙酸乙酯提取后,GC/MS/MS测定分析,以胆固醇分子离子为母离了,以其子离子为定量分析的碎片离子。线性好,回收率高,方法可靠。 相似文献
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《Journal of mass spectrometry : JMS》2002,37(9):1002-1011
In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of mass spectrometry. Each bibliography is divided into 11 sections: 1 Books, Reviews & Symposia; 2 Instrumental Techniques & Methods; 3 Gas Phase Ion Chemistry; 4 Biology/Biochemistry: Amino Acids, Peptides & Proteins; Carbohydrates; Lipids; Nucleic Acids; 5 Pharmacology/Toxicology; 6 Natural Products; 7 Analysis of Organic Compounds; 8 Analysis of Inorganics/Organometallics; 9 Surface Analysis; 10 Environmental Analysis; 11 Elemental Analysis. Within each section, articles are listed in alphabetical order with respect to author (4 Weeks journals ‐ Search completed at 3rd. July 2002) 相似文献
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运用不含手性碳的非对称化合物S-BNP酸(S-phosphorsaeure-(1,1'-binaphthyl-2,2'-diylester))作反应试剂用快原子轰击反应质谱法(FAB-RMS)测定手性化合物的绝对构型.发现非对称手性化合物可与不对称手性化合物在质谱中发生立体选择性反应,S-BNP酸可作为一种新的反应试剂来测定手性化合物的绝对构型. 相似文献
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Meija J 《Analytical and bioanalytical chemistry》2005,381(1):11-12
For the first time this year, we would like to invite you to participate in the Analytical Challenge, which is a series of puzzles to entertain and challenge our readers. We hope that you not only find this feature stimulating but that it provides you with points of further interest for your work and study. And please note: there is a prize to be won (a Springer book from our catalogue up to a value of € 75).These Analytical Challenges are published every two months. Two years ago, we first began with a series of spectroscopy challenges by Ernö Pretsch and Renato Zenobi, which may still be viewed on the Springer chemistry website www.springeronline.com. Mass spectrometry is the topic in the present challenge. Please read on... 相似文献
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