面向应用型人才培养的仪器分析实验教学改革

为实现应用型人才培养目标,在“仪器分析实验”课程教学体系中增加了设计性实验项目,以促进对学生的创新和实践能力的培养。具有针对性的合理选题,注重理论联系实际;倡导启发式教学,结合多媒体教学丰富课堂;建立科学全面的考核评价体系,培养学生创新意识和实践能力。实践教学改革凸显了设计性实验在仪器分析教学当中的重要作用,同时也凸显出此课程教学计划的科学性、教学内容的先进性以及教学手段的连贯性。     

仪器分析课程的教学改革与探索

针对仪器分析课程的基本特点及教学中存在的问题,在教学内容调整、教学方法改革以及考核方式多样化等方面进行了初步尝试。     

仪器分析课程教学内容和教学方式改革的几点思考

结合学科发展趋势和专业特点,针对近年来仪器分析课程教学中存在的问题,初步探讨了教学内容、教学模式和考核评价方式等方面的改革思路,通过更新、完善现代仪器分析化学课程的理论教学内容,提高教学质量,使学生掌握仪器分析的专业基础知识、具备优良的专业素质,同时在教学中还应融入思政元素,实现专业课的育人功能。     

仪器分析课程教学改革与实践

介绍华中农业大学理学院对仪器分析课程教学进行的各项改革和实践。不断创新教学方法和教学手段,提出了“五位一体”的教学新模式和多元化的考核体系。学生的学习兴趣、教学质量和教学效果不断提高。     

国外仪器分析课程内容与教学方法的研究

针对国内仪器分析教学中存在的教材相对陈旧、课程内容未能体现学科的最新发展、缺乏有效的考核评价方式和标准等问题,本文收集了国外部分代表性高校化学专业与仪器分析教学相关的现使用教材和课程体系,通过梳理和比较分析,归纳出其特点,希望能对今后仪器分析课程建设、教学内容完善以及考核评价标准的改革提供有益的借鉴。     

高职“仪器分析及实验”循环进阶教学模式的开发与应用

通过分析"仪器分析"教学内容及教学对象的特点,针对"仪器分析"课程传统教学方法存在的弊端进行改革。从教学体系、教学内容、教学方法等多方面设计"仪器分析及实验"课程,构建出以学生为主体、基于认知规律、多层次阶梯式的教学模式,以提升学生对仪器分析方法的实际应用能力。     

“以学生为中心”的普通化学课程教学模式探索与实践

结合普通化学课程特点及教学实践,深入分析了传统“教师中心”课程教学中普遍存在的问题,阐述了进行“以学生为中心”课程教学改革的必要性。从教学理念、教学内容、教学过程及考核评价等4方面构建了“以学生为中心”的普通化学课程教学体系。提出了通过简约化、项目化、生活化及开放性原则优选整合教学内容,优化了“四环节六步骤”教学过程,完善了多元多维互动教学评价办法。     

慕课视阈下高职“药物合成技术”课程改革的探索与实践

慕课的出现引发了大学教学模式变革。根据“药物合成技术”课程性质、特点及培养目标,坚持企业深度参与和学情分析原则,整合选择适当的教学内容,将其分为基础模块和拓展模块2部分,根据每个模块内容特点,选择不同的教学及组织方法,改进考核评价标准。     

“单晶结构分析实践”课程的教学探索

介绍了为研究生开设“单晶结构分析实践”课程的背景和必要性,阐述了该课程的课程定位、教学内容、教学方法和考核评价体系.实践证明,采用理论与实践并重的课程教学模式,有利于提高学生的综合素养和单晶结构分析能力;针对不同内容采用灵活多样的教学方法,可以激发学生的学习兴趣,调动学生的学习积极性;多模式的过程性考核评价体系有助于提高课程的教学质量.     

仪器分析课程教学探索

从仪器分析课程的特点出发，针对教学内容、教学方法、教学手段等提出一些认识，以期引起教育工作者对仪器分析教学的思考。     

多环芳二酐型聚酯亚胺膜的透气性能

多环芳二酐型聚酯亚胺膜的透气性能李悦生，丁孟贤，徐纪平（浙江大学高分子科学与工程研究所，杭州，３１００２７）（中国科学院长春应用化学研究所）关键词聚醚酰亚胺，聚酯酰亚胺，膜，透气性通常的聚酰亚胺加工性能较差，在芳环二酐的苯环间引入醚键等柔性基团后，其...     

Determination and study on residue and dissipation of benazolin-ethyl and quizalofop-p-ethyl in rape and soil

A QuEChERS (quick, easy, cheap, effective, rugged, and safe) method for the determination of benazolin-ethyl and quizalofop-p-ethyl in rape and soil by high-performance liquid chromatography-tandem mass spectrometry has been developed in this study. The residue and dissipation of benazolin-ethyl and quizalofop-p-ethyl in rape and soil were determined with the developed method. The half-lives of benazolin-ethyl in rape straw and soil were 3.7–5.1 days and 14.3–26.3 days, respectively. The half-lives of quizalofop-p-ethyl in rape straw and soil were 5.0-6.1 days and 0.3–9.7 days, respectively. The residue of benazolin-ethyl and quizalofop-p-ethyl in rapeseed and soil were below the detection limit (i.e., 0.5?mg?kg^?1, the maximum residue level of European Union for quizalofop-p-ethyl).     

微量元素与疾病诊断治疗的研究现状及展望

对国内外微量元素与疾病的关系及其诊断治疗的研究现状及研究动向进行了综述，包括：微量元素与地方病、癌肿、心血管病、糖尿病、眼病、神经系统病等。参考文献72篇。     

Conformations and steric and stacking interactions of trisubstituted ureas and thioureas with alkyl and phenyl groups

The monomeric ν(N—H) vibrations of various trisubstituted ureas of the R₂UPh type and -thioureas of the R₂TUPh type have been studied. The trans—out isomerism in the former and the trans—out—cis isomerism in the latter are discussed from the point of view of steric effect. The monomeric ν(N—H) vibrations of RPhUPh and RPhTUPh are also examined. The single band appearing in the spectrum of both ureas is characteristic of the cis form; this suggests the existence of phenyl—phenyl interaction (the stacking interaction proposed by Galabov et al. [10]). Behavior of ν(N—H) vibrations at several concentrations is shown to be clearly different in the three forms (trans, out and cis). The presence of the cis form is confirmed by solvent effect experiments.     

Ti-V基储氢合金及其氢化物的物相结构与组分优化设计

Ti-V基储氢合金在室温、常压下即可表现出良好的储氢特性,且质量储氢容量明显高于传统AB₅型储氢合金,从而在氢气的精制和回收、运输和储存及热泵等方面有较早的应用。 此外,在混合气体分离、核反应堆中处理氢的同位素、镍氢电池及燃料电池负极材料等方面也得到了广泛的研究与关注。 基于目前Ti-V基储氢合金的研究现状,概述了该类合金的优势、限制性因素(包括成因)及改性手段。 此外,为了进一步理解Ti-V基合金储氢机理、构建合金组分与储氢特性之间的对应关系,本工作重点围绕Ti-V基储氢合金及其氢化物的结构、组分优化设计展开综述,并对其未来研究方向做出展望。     

Ferrocene and ferrocenium modified clays and their styrene and EVA composites

In this work, ferrocene- and ferrocenium-containing salts were employed to modify montmorillonite. X-ray measurements show an increase in the interlayer spacing upon clay modification, which means that the larger and more organophilic cations were inserted into the gallery space of montmorillonite. Attempts to prepare nanocomposites of polystyrene and ethylene vinyl acetate copolymers lead to immiscible systems; the morphology of these systems was elucidated with TEM, XRD and cone calorimetry. The thermal stability of the composites is greater than that of the virgin polymer.     

钒与糖代谢及糖尿病

微量元素钒作为生物体内必需元素，经证实有很重要的生理学功能，与机体糖代谢有十分密切的关系，且能降低糖尿病动物模型的高血糖，极有可能被开发为治疗糖尿病的药物。     

Synthesis and Optical and Redox Properties of Symmetric and Asymmetric BODIPYs

Herein, we present the synthetic route and the photophysical, electrochemical as well as laser properties of novel red‐emitting boron‐dipyrromethenes (BODIPYs) bearing arylethyne moieties. Such functionality is added along the main axis of the chromophore leading to single‐ and double‐substituted derivatives. The relationship between the dye structure and the lasing properties is studied in detail with the help of the photophysical and electrochemical properties as well as quantum mechanical simulations. The asymmetric substitution of the parent dye induces inhomogeneities in the charge distribution, which leads to an overall loss of the fluorescence capacity, mainly in polar media. Such non‐radiative deactivation processes can be softened by decreasing the electron‐donor ability of the substituent or even avoided by symmetrical substitution. Thus, grafting of the arylethyne moieties at the longitudinal axis of the indacene core results in an effective strategy to develop red‐edge BODIPYs with highly efficient and photostable laser emission.     

Synthesis of Tyrosol and Hydroxytyrosol Glycofuranosides and Their Biochemical and Biological Activities in Cell-Free and Cellular Assays

Tyrosol (T) and hydroxytyrosol (HOT) and their glycosides are promising candidates for applications in functional food products or in complementary therapy. A series of phenylethanoid glycofuranosides (PEGFs) were synthesized to compare some of their biochemical and biological activities with T and HOT. The optimization of glycosylation promoted by environmentally benign basic zinc carbonate was performed to prepare HOT α-L-arabino-, β-D-apio-, and β-D-ribofuranosides. T and HOT β-D-fructofuranosides, prepared by enzymatic transfructosylation of T and HOT, were also included in the comparative study. The antioxidant capacity and DNA-protective potential of T, HOT, and PEGFs on plasmid DNA were determined using cell-free assays. The DNA-damaging potential of the studied compounds for human hepatoma HepG2 cells and their DNA-protective potential on HepG2 cells against hydrogen peroxide were evaluated using the comet assay. Experiments revealed a spectrum of different activities of the studied compounds. HOT and HOT β-D-fructofuranoside appear to be the best-performing scavengers and protectants of plasmid DNA and HepG2 cells. T and T β-D-fructofuranoside display almost zero or low scavenging/antioxidant activity and protective effects on plasmid DNA or HepG2 cells. The results imply that especially HOT β-D-fructofuranoside and β-D-apiofuranoside could be considered as prospective molecules for the subsequent design of supplements with potential in food and health protection.