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Wenpei Fan Wenbo Bu Zhen Zhang Bo Shen Hui Zhang Qianjun He Dalong Ni Zhaowen Cui Kuaile Zhao Jiwen Bu Jiulin Du Jianan Liu Jianlin Shi 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2015,127(47):14232-14236
Multifunctional stimuli‐responsive nanotheranostic systems are highly desirable for realizing simultaneous biomedical imaging and on‐demand therapy with minimized adverse effects. Herein, we present the construction of an intelligent X‐ray‐controlled NO‐releasing upconversion nanotheranostic system (termed as PEG‐USMSs‐SNO) by engineering UCNPs with S‐nitrosothiol (R‐SNO)‐grafted mesoporous silica. The PEG‐USMSs‐SNO is designed to respond sensitively to X‐ray radiation for breaking down the S N bond of SNO to release NO, which leads to X‐ray dose‐controlled NO release for on‐demand hypoxic radiosensitization besides upconversion luminescent imaging through UCNPs in vitro and in vivo. Thanks to the high live‐body permeability of X‐ray, our developed PEG‐USMSs‐SNO may provide a new technique for achieving depth‐independent controlled NO release and positioned radiotherapy enhancement against deep‐seated solid tumors. 相似文献
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Dr. Ivan Halasz Andreas Puškarić Dr. Simon A. J. Kimber Patrick J. Beldon Dr. Ana M. Belenguer Frank Adams Dr. Veijo Honkimäki Prof. Robert E. Dinnebier Bhavnita Patel Prof. William Jones Dr. Vjekoslav Štrukil Prof. Tomislav Friščić 《Angewandte Chemie (International ed. in English)》2013,52(44):11665-11665
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Inside Back Cover: New Insights into the Hexaphenylethane Riddle: Formation of an α,o‐Dimer (Angew. Chem. Int. Ed. 13/2015) 下载免费PDF全文
Yasuto Uchimura Dr. Takashi Takeda Dr. Ryo Katoono Prof. Dr. Kenshu Fujiwara Prof. Dr. Takanori Suzuki 《Angewandte Chemie (International ed. in English)》2015,54(13):4125-4125
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Inside Cover: Trimethylaluminum: Bonding by Charge and Current Topology (Angew. Chem. Int. Ed. 46/2015) 下载免费PDF全文
Dr. Hans‐Georg Stammler M. Sc. Sebastian Blomeyer Priv.‐Doz. Dr. Raphael J. F. Berger Prof. Dr. Norbert W. Mitzel 《Angewandte Chemie (International ed. in English)》2015,54(46):13470-13470
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Inside Back Cover: Lability‐Controlled Syntheses of Heterometallic Clusters (Angew. Chem. Int. Ed. 11/2014) 下载免费PDF全文
Dr. Graham N. Newton Dr. Kiyotaka Mitsumoto Rong‐Jia Wei Fumichika Iijima Dr. Takuya Shiga Prof. Dr. Hiroyuki Nishikawa Prof. Dr. Hiroki Oshio 《Angewandte Chemie (International ed. in English)》2014,53(11):3033-3033
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Cover Picture: Plumbonacrite Identified by X‐ray Powder Diffraction Tomography as a Missing Link during Degradation of Red Lead in a Van Gogh Painting (Angew. Chem. Int. Ed. 12/2015) 下载免费PDF全文
Frederik Vanmeert Dr. Geert Van der Snickt Prof. Dr. Koen Janssens 《Angewandte Chemie (International ed. in English)》2015,54(12):3523-3523
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Back Cover: Oxidative Metalation as a Route to Size‐Mismatched Macrocyclic Complexes: Osmium Corroles (Angew. Chem. Int. Ed. 52/2014) 下载免费PDF全文
Dr. Abraham B. Alemayehu Dr. Kevin J. Gagnon Prof. Dr. James Terner Prof. Dr. Abhik Ghosh 《Angewandte Chemie (International ed. in English)》2014,53(52):14612-14612
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Inside Back Cover: Ice Melting to Release Reactants in Solution Syntheses (Angew. Chem. Int. Ed. 13/2018) 下载免费PDF全文
Hehe Wei Dr. Kai Huang Le Zhang Prof. Dr. Binghui Ge Dr. Dong Wang Jialiang Lang Dr. Jingyuan Ma Dr. Da Wang Shuai Zhang Prof. Dr. Qunyang Li Ruoyu Zhang Naveed Hussain Prof. Dr. Ming Lei Prof. Dr. Li‐Min Liu Prof. Dr. Hui Wu 《Angewandte Chemie (International ed. in English)》2018,57(13):3519-3519