共查询到20条相似文献,搜索用时 328 毫秒
1.
Chemistry of Heterocyclic Compounds - The high-energy compound 4,6-diazido-N-(4,6-diazido-1,3,5-triazin-2-yl)-1,3,5-triazin-2-amine was obtained in high yield by azidation of... 相似文献
2.
Tomonari Tanaka Tomonori Wada Masato Noguchi Masaki Ishihara Atsushi Kobayashi Takayuki Ohnuma 《Journal of carbohydrate chemistry》2013,32(8):634-646
A novel sugar adduct, 4,6-dimethoxy-1,3,5-triazin-2-yl β-d-glucosaminide (GlcN-β-DMT), has been prepared by the reaction of d-glucosamine (GlcN) and 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-morpholinium chloride (DMT-MM). The adduct was recognized by exo-β-d-glucosaminidase (GlcNase) from Amycolatopsis orientalis and transferred the GlcN moiety, giving rise to the corresponding glucosaminides. This chemo-enzymatic process was successfully applied to d-galactosamine (GalN). GalN-β-DMT prepared directly from GalN and DMT-MM behaved as an efficient glycosyl donor for transfer of the GalN moiety catalyzed by the same enzyme. The introduction of the 4,6-dimethoxy-1,3,5-triazin-2-yl leaving group to the anomeric center significantly enhanced transglycosylating ability, resulting in the efficient glycosidase-catalyzed synthesis of glycosaminides. 相似文献
3.
Mikolaichuk O. V. Sharoyko V. V. Popova E. A. Protas A. V. Fonin A. V. Anufrikov Yu. A. Malkova A. M. Shmaneva N. T. Ostrovskii V. A. Molchanov O. E. Maistrenko D. N. Semenov K. N. 《Russian Chemical Bulletin》2022,71(5):1050-1056
Russian Chemical Bulletin - ({5-[4,6-Di(aziridin-1-yl)-1,3,5-triazin-2-yl]amino}-2,2-dimethyl-1,3-dioxan-5-yl)-methyl 2-(5-phenyl-2H-tetrazol-2-yl)acetate was synthesized and characterized. The... 相似文献
4.
V. V. Bakharev A. A. Gidaspov E. V. Selezneva I. V. Ul’yankina D. B. Krivolapov I. A. Litvinov O. S. Eltsov 《Chemistry of Heterocyclic Compounds》2011,46(11):1386-1392
The reaction of 6-R-4-methoxy-1,3,5-triazin-2-ylnitroformaldoximes with dimethyl malonate gives the zwitterionic 4-methoxycarbonyl-3-(4-R-6-methoxy-1,3,5-triazin-2-yl)-4,5-dihydroisoxazol-5-ones.
X-ray structural analysis has been carried out on the zwitterionic 4-methoxycarbonyl-3-(4-methoxy-6-piperidino-1,3,5-triazin-2-yl)-4,5-dihydroisoxazol-5-one. 相似文献
5.
Mina Jung Kyung Hyung Lee Prof. Dr. Jun Yeob Lee 《Chemistry (Weinheim an der Bergstrasse, Germany)》2020,26(21):4816-4821
Benzofurocarbazole moieties are commonly used donor structures in the design of thermally activated delayed fluorescence (TADF) emitters. However, only 5 H-benzofuro[3,2-c]carbazole (34BFCz) has been reported and, to the best of our knowledge, no other benzofurocarbazole derivatives have been covered in the literature. In the present study, two further benzofurocarbazole moieties, 12 H-benzofuro[3,2-a]carbazole (12BFCz) and 7 H-benzofuro[2,3-b]carbazole (23BFCz), have been synthesized to investigate the effect of the donor structure on the photophysics and device parameters of TADF emitters. Two benzofurocarbazole-derived TADF emitters, 12-(2-(4,6-diphenyl-1,3,5-triazin-2-yl)phenyl)-12 H-benzofuro[3,2-a]carbazole (o12BFCzTrz) and 7-(2-(4,6-diphenyl-1,3,5-triazin-2-yl)phenyl)-7 H-benzofuro[2,3-b]carbazole (o23BFCzTrz), have been compared with 5-(2-(4,6-diphenyl-1,3,5-triazin-2-yl)phenyl)-5 H-benzofuro[3,2-c]carbazole (oBFCzTrz). The benzofurocarbazole donor structure governs the TADF characteristics, such as charge-transfer property and emission color. The 12BFCz donor has proved to be effective in blue-shifting the emission color, and 34BFCz has proven useful for improving the external quantum efficiency (EQE). The 12BFCz-derived o12BFCzTrz showed blue-shifted color coordinates of (0.159, 0.288), compared to (0.178, 0388) for o23BFCzTrz and (0.169, 0.341) for oBFCzTrz. The 34BFCz-derived oBFCzTrz exhibited an EQE of 22.9 %, compared to 19.2 % for o12BFCzTrz and 21.1 % for o23BFCzTrz. 相似文献
6.
《Tetrahedron: Asymmetry》2005,16(22):3667-3671
Three new substituted BINOL ligands (R)-3-[4,6-bis(dimethylamino)-1,3,5-triazin-2-yl]-1,1′-bi-2-naphthol (R)-1, (R)-3,3′-bis[4,6-bis(dimethylamino)-1,3,5-triazin-2-yl]-1,1′-bi-2-naphthol (R)-2 and 2,4-bis(2,2′-dihydroxy-1,1′-binaphthalen-3-yl)-6-(p-tolyl)-1,3,5-triazine (R,R)-3 have been obtained by directed ortho-lithiation or Suzuki cross-coupling process. Ligand (R)-1 shows improved catalytic properties for the asymmetric diethylzinc addition to aromatic aldehydes. 相似文献
7.
V. V. Bakharev A. A. Ghidaspov D. B. Krivolapov E. V. Mironova I. A. Litvinov 《Chemistry of Heterocyclic Compounds》2006,42(8):1051-1058
2-Amino-4-azido-1,3,5-triazin-6(1H)-ones were synthesized by successive substitution of the trinitromethyl groups in 2-amino-4,6-bis(trinitromethyl)-1,3,5-triazines
under the influence of azide and nitrite ions. Interaction of 2-amino-4-azido-1,3,5-triazin-6(1H)-ones with bases led to the
azido-tetrazole tautomeric conversion give salts of 5-aminotetrazolo[1,5-a]-1,3,5-triazin-7-one.
__________
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1211–1219, August, 2006. 相似文献
8.
Mikhailichenko S. N. Chesnyuk A. A. Konyushkin L. D. Zaplishnyi V. N. 《Russian Chemical Bulletin》2003,52(10):2157-2160
Reactions of (4,6-disubstituted 1,3,5-triazin-2-yl)trimethylammonium chlorides with glycine sodium salt in the presence of Et3N afforded bis(triazin-2-yl) ethers instead of the expected triazinylaminoacetic acids. The structures of the resulting compounds were established by the independent synthesis, spectroscopic data, and X-ray diffraction analysis. 相似文献
9.
Wang Q Haughey SA Sun YM Eremin SA Li ZF Liu H Xu ZL Shen YD Lei HT 《Analytical and bioanalytical chemistry》2011,399(6):2275-2284
A fluorescence polarization immunoassay (FPIA) based on a polyclonal antibody was developed for the determination of melamine
in milk. To obtain an antibody with improved sensitivity and specificity, 6-hydrazinyl-1,3,5-triazine-2,4-diamine was coupled
to bovine serum albumin and used as the immunogen for the rabbit immunization. Three fluorescein-labeled melamine tracers
with different structures and spacer bridges were synthesized. The structural effect of the tracers on the assay characteristics
was investigated. 6-(4,6-Diamino-1,3,5-triazin-2-ylamino)-N-(2-(3-(3′,6′-dihydroxy-3-oxo-2,3-dihydrospiro[indene-1,9′-xanthene]-5-yl)thioureido)ethyl)hexanamide demonstrated better
sensitivity than 5-(2-(4,6-diamino-1,3,5-triazin-2-yl)hydrazinecarbothioamido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid and 3-(4,6-diamino-1,3,5-triazin-2-ylthio)-N-(2-(3-(3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-yl)thioureido)ethyl)propanamide. The limit of detection (10% inhibition) of the FPIA
was 9.3 ng mL-1 and the IC50 (50% inhibition) value was 164.7 ng mL-1. The antibody in the FPIA showed 21.2% cross-reactivity to the fly-killing insecticide cyromazine, but had no cross-reactivity
to other natural structurally related compounds. Recoveries, measured in spiked milk and milk powder samples, ranged from
79.4 to 119.0%. Milk samples fortified with melamine were analyzed by this method and confirmed by high-performance liquid
chromatography–mass spectrometry. Excellent recoveries and correlation with spiked levels were observed, suggesting that this
immunoassay could be applied to the screening of melamine residues in milk and milk powder after a simple dilution procedure.
相似文献
10.
Drew MG Hill C Hudson MJ Iveson PB Madic C Youngs TG 《Dalton transactions (Cambridge, England : 2003)》2004,(2):244-251
The extracting agent 2,6-bis(4,6-di-pivaloylamino-1,3,5-triazin-2-yl)-pyridine (L(5)) in n-octanol was found, in synergy with 2-bromodecanoic acid, to give D(Am)/D(Eu) separation factors (SFs) between 2.4 and 3.7 when used to extract the metal ions from 0.02-0.12 M HNO(3). Slightly higher SFs (4-6) were obtained in the absence of the synergist when the ligand was used to extract Am(III) and Eu(III) from 0.98 M HNO(3). In order to investigate the possible nature of the extracted species crystal structures of L(5) and the complex formed between Yb(III) with 2,6-bis(4,6-di-amino-1,3,5-triazin-2-yl)-pyridine (L(4)) were also determined. The structure of L(5) shows 3 methanol solvent molecules all of which form 2 or 3 hydrogen bonds with triazine nitrogen atoms, amide nitrogen or oxygen atoms, or pyridine nitrogen atoms. However, L(5) is relatively unstable in metal complexation reactions and loses amide groups to form the parent tetramine L(4). The crystal structure of Yb(L(4))(NO(3))(3) shows ytterbium in a 9-coordinate environment being bonded to three donor atoms of the ligand and three bidentate nitrate ions. The solvent extraction properties of L(4) and L(5) are far inferior to those found for the 2,6-bis-(1,2,4-triazin-3-yl)-pyridines (L(1)) which have SF values of ca. 140 and theoretical calculations have been made to compare the electronic properties of the ligands. The electronic charge distribution in L(4) and L(5) is similar to that found in other terdentate ligands such as terpyridine which have equally poor extraction properties and suggests that the unique properties of L(1) evolve from the presence of two adjacent nitrogen atoms in the triazine rings. 相似文献
11.
Beata Kolesińska Katarzyna Kasperowicz Adam Mazur Zbigniew J. Kamiński 《Tetrahedron letters》2010,51(1):20-4513
The concept of a chiral coupling reagent for the enantioselective synthesis of peptides with a predictable configuration and enantiomeric purity from racemic substrates is presented. The reagent was prepared by treatment of strychninium tetrafluoroborate with 2-chloro-4,6-dimethoxy-1,3,5-triazine in the presence of sodium bicarbonate yielding N-(4,6-dimethoxy-1,3,5-triazin-2-yl)strychninium tetrafluoroborate in high yield, which is stable at room temperature, and in a broad range of solvents gave enriched Z-Ala-Phe-OMe (dr from 95/5 to 60/40) in high yield with d-configuration on the alanine residue starting from rac-Z-Ala-OH. 相似文献
12.
E. Yu. Shasheva N. I. Vikrishchuk L. D. Popov S. A. Borodkin 《Russian Journal of Organic Chemistry》2017,53(10):1573-1577
4-(2-Hydroxyphenyl)-1,3,5-triazin-2-ylcyanamides reacted with sodium azide to give N-(tetrazol-5-yl)-1,3,5-triazin-2-amines, and their reaction with allyl bromide afforded allyl(1,3,5-triazin-2-yl)cyanamides. Acetylation of 4-(2-hydroxyphenyl)-1,3,5-triazin-2-amines involved only the amino group with formation of diacetylamino derivatives, whereas the phenolic hydroxy group remained intact. The reaction of triazinamines with 2,5-dimethoxytetrahydrofuran in the presence of P2O5 gave pyrrolyl-substituted triazines. 相似文献
13.
A. V. Shastin T. I. Godovikova B. L. Korsunskii 《Chemistry of Heterocyclic Compounds》2003,39(3):354-356
As a result of nucleophilic substitution of the trinitromethyl groups in 2,4,6-tris(trinitromethyl)-1,3,5-triazine, the corresponding monoazido and diazido derivatives have been synthesized. The reaction of the starting triazine with hydrazine acetate in the presence of trifluoroacetic acid leads to 1-acetyl-2,2-bis[4,6-bis(trinitromethyl)-1,3,5-triazin-2-yl]hydrazine. 相似文献
14.
Bodige S. Ravula P. Gulipalli K. Ch. Endoori S. Cherukumalli P. Koteswara Rao Chandra J. N. Narendra Sharath Seelam N. 《Russian Journal of General Chemistry》2020,90(7):1322-1330
Russian Journal of General Chemistry - A series of novel N-{2-fluoro-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)methyl]phenyl} carboxamide derivatives has been synthesized, and their molecular structures... 相似文献
15.
V. V. Bakharev A. A. Gidaspov E. V. Selezneva V. E. Parfenov I. V. Ulˈyankina I. S. Nazarova Yu. T. Palatova O. S. Elˈtsov 《Chemistry of Heterocyclic Compounds》2012,47(10):1258-1267
Heating 4-R-methoxy-1,3,5-triazin-2-ylnitroformaldoximes with nitriles leads not to the formation of 1,2,4-oxadiazoles but
rather to dimerization of the intermediate 1,3,5-triazinylnitrile oxides to give furoxanes. The reaction of 4-R-6-methoxy-1,3,5-triazin-2-ylnitroformaldoximes
with ammonia and amines gives 1,3,5-triazinylamidoximes, which upon acylation and subsequent intramolecular cyclization yield
(5-R-1,2,4-oxadiazol-3-yl)-1,3,5-triazines. 相似文献
16.
Tanaka T Noguchi M Kobayashi A Shoda S 《Chemical communications (Cambridge, England)》2008,(17):2016-2018
A novel activated glycosidic compound, 4,6-dimethoxy-1,3,5-triazin-2-yl beta-lactoside (DMT-beta-Lac), which can be prepared directly from lactose in water without using any protecting groups, was found to be an efficient glycosyl donor for enzymatic glycosylation catalyzed by an endo-1,4-beta-glucanase. 相似文献
17.
Dissociation enhanced lanthanide fluoroimmunoassay (DELFIA) technique based on EDTA-Eu(3+) derivative biolabels is the most widely used time-resolved luminescence bioassay technique for clinical diagnosis, but its major drawback is that the conventional luminescence enhancement solution of EDTA-Eu(3+) requires UV excitation (<360 nm). In this work, three new visible-light-excited luminescence enhancement solutions are developed and their luminescence response behaviors to EDTA-Eu(3+) are systematically investigated. The new solutions were prepared by co-dissolving a newly synthesized tetradentate β-diketone, 1,2-bis[8'-(1',1',1',2',2',3',3'-heptafluoro-4',6'-hexanedion-6'-yl)-naphth-2'-yl]-benzene (BHHNB), and one of three derivatives of triazine, 2-(N,N-diethylanilin-4-yl)-4,6-bis(3,5-dimethylpyrazol-1-yl)-1,3,5-triazine (DPBT), 2-(N,N-diethylanilin-4-yl)-4,6-bis(3-methylpyrazol-1-yl)-1,3,5-triazine (MPBT) or 2-(N,N-diethylanilin-4-yl)-4,6-bis(pyrazol-1-yl)-1,3,5-triazine (BPT), in a weakly acidic aqueous buffer at pH 3.2 containing 0.1% Triton X-100. These solutions showed sensitive and rapid luminescence responses to non-luminescent EDTA-Eu(3+) by the formation of the ternary Eu(3+) complexes, BHHNB-Eu(3+)-DPBT, BHHNB-Eu(3+)-MPBT and BHHNB-Eu(3+)-BPT. These complexes have long luminescence lifetimes (>500 μs) and a wide excitation wavelength range from UV to visible light with the excitation peaks at 390, 400 and 420 nm, respectively, which enabled the solutions to be used as visible-light-excited luminescence enhancement solutions for the highly sensitive time-resolved luminescence detection of EDTA-Eu(3+). 相似文献
18.
V. V. Bakharev A. A. Gidaspov E. V. Peresedova D. B. Krivolapov E. V. Mironova I. A. Litvinov 《Chemistry of Heterocyclic Compounds》2009,45(9):1075-1080
1,3,5-Triazinylnitrile oxides were prepared in situ from 2-R-4-R′-1,3,5-triazin-6-ylnitroformaldoximes and were treated with
substituted acetylenes to give 3,5-disubstituted isoxazoles. The X-ray data obtained for 5-hydroxymethyl-3-(4′-dimethylamino-2′-methoxy-1,3,5-triazin-6′-yl)isoxazole
is discussed. 相似文献
19.
Steven A. Raw 《Tetrahedron letters》2009,50(8):946-6602
A simple, robust and high-yielding process for the preparation of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium tetrafluoroborate (DMTMM BF4) and hexafluorophosphate (DMTMM PF6) has been developed, which avoids the use of expensive or unusual reagents. 相似文献
20.
Hioki K Kobayashi H Ohkihara R Tani S Kunishima M 《Chemical & pharmaceutical bulletin》2004,52(4):470-472
Weinreb amides were successfully prepared from the corresponding carboxylic acids using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM) in the solvents, methanol, isopropyl alcohol, and acetonitrile, which can solubilize DMT-MM. A variety of carboxylic acids were converted to the corresponding Weinreb amides in excellent yields by simply mixing with DMT-MM and N,O-dimethylhydroxylamine hydrochloride. 相似文献