Synthesis and Characterization of the Terpolymer of Itaconic Acid with Acrylamide and 2-Acrylamido-2-methylpropanesulfonic Acid

The thermal stability of the polymer is of great significance in paper, ceramics and oil industry1. Conventional polymers such as polyanionic cellulose can not meet high temperature limitations2-4. Aggour5-6 and Collette7 etc. have conducted extensive research on synthesis and characterizations of the copolymer or terpolymer containing 2-acrylamido-2-methyl-1-propane sulfonic acid (AMPS). Till now, very few research works have been reported on the terpolymer of itaconic acid (IA), acrylamid…     

Synthesis and Properties of A Novel Triphenylamine Derivative

A novel triphenylamine derivative of 4, 4‘-bis-[2-[4-[N,N-bis-(4-methoxyphenyl-amino)] phenyl-l-yl]-viny1-1-y1]-1, 1‘-biphenyl (DMPAVBI) was synthesized. The chemical structure was confirmed by IR, ^1H NMR spectroscopy and elemental analysis. Its properties were studied by UV-Vis spectroscopy, photoluminescence spectroscopy and cyclic voltammetry methods.     

Synthesis of Cholesterol Derivative with Amino Acid as Hydrophilic Group and the Vesicles Prepared Therefrom

Cholesterolisoneofthemainconstituentsofmembranelipidsandhasbeenconsideredtogovernthemembranefluidityandpermeabilityofsolutes'.Inthecourseofstudyonliposomesconstructedbyphospholipidsasmodelbiomembraneordrugdeliverysystem,itwasalsofoundthatthestabilityofliposomeswasenhancedbyincorporationofcholesterolintothelipidbilayerZ".Allthesepropertiesofcholesterolinmembranechemistryarecausedbyitsuniquesmicture,inwhichtherigidandflatsteroidalringshowsgoodcompatibilitywithlipid.DuetotheeXtraordinaryfijnctio…     

Synthesis, Structure and Characterization of Manganese(Ⅱ) Coordination Polymer with Camphoric Acid and 1,10-Phenanthroline

A novel coordination polymer, Mn(H2O)(CA)(Phen)·H2O(CA=camphoric acid, Phen=1,10-phenanthroline), was synthesized and its crystal structure was determined by single crystal X-ray diffraction. Six-coordinated Mn(Ⅱ) atoms are linked with carboxyl groups from camphoric acid ligands to form infinite one-dimensional chains. These chains are packed by means of hydrogen bonding and π-π stacking, forming a three-dimensional structure. IR, thermogravimetric analysis and magnetic susceptibility data for Mn(H2O)(CA)(Phen)·H2O are given.     

Synthesis,Characterization and Antitumor Activity in Vitro of Cd（Ⅲ）Complex with Chelidamic Acid

A novel complex [Cd4(HCAM)4(H2O)8] of Cd(Ⅲ) withchelidamic acid (H3CAM) was synthesized by the hydrothermal method and characterized with IR and emission spectra.The crystal structure was determined based on single-crystal X-ray diffraction data.It crystallizes in monoclinic,space group C2/c with a=17.538(5),b=12.916(4),c=16.505(7),β=100.690(14)o,V=3674(2) 3,Z=8,C14 H14 Cd2N2O14,Mr=659.07,Dc=2.383 g/cm 3,μ=2.400 mm-1,S=1.000,F(000)=2560,the final R=0.0242 and wR=0.0581 for 3656 observed reflections with I>2σ(I).The inhibition of the complex against K562 and HL60 cells was determined by MTT assay.The results showed that the concentration of complex was positively correlated with inhibitions against K562 and HL60 cell lines,but inhibitory effects are relatively weak.IC 50 concentration of the title complex on K562 and HL60 cells is 15 and 5 μg/mL,respectively.     

Synthesis, Structure and Characterization of Manganese（ Ⅱ ） Coordination Polymer with Camphoric Acid and 1, 10-Phenanthroline

IntroductionThe syntheses of metal-organic coordination poly-mers have been attracting increasing attention owing tothe potential applications of their functional materials incatalysis,non-linear optics,magnetism sensors andmolecular recognition[1—7].Coordination polymers crys-tallized from polyaromatic acids and metal-ions are ofgreat interest for their polymeric structures and porousproperties[8—12].Their network topologies based on mo-lecular building blocks are usually controlled and mod…     

A Novel 5-Fluorouracil Salt of 12-Silicatungstic Acid： Synthesis, Structure Characterization and Antitumor Activity

A novel 5-fluorouracil salt of 12-silicatungstic acid was synthesized and characterized by means of elemental analysis, IR,^1H NMR and ^183W NMR spectra. The antitumor activity and toxicity of the complex have been evaluated both in vitro and in vivo.     

A Fe(Ⅱ) Coordination Polymer Based on 1,10-Phenanthroline Derivative and Oxalic Acid:Synthesis,Structure,and Properties

A Fe-based coordination polymer,[Fe(C₂O_4)_0.5(4-NCP)]_n·2nH₂O (1,4-HNCP=2-(4-carboxyphenyl)-1H-imidazo(4,5-f)-(1,10)phenanthroline,H₂C₂O₄=oxalic acid),was hydrothermally synthesized and characterized by infrared spectrum,elemental analysis,single-crystal X-ray diffraction,power X-ray diffraction,and UV-vis absorption spectrum.Structural analyses reveal that polymer 1 possesses a (4,4)-connected 2D network.In addition,1 shows photocatalytic activity toward the degradation of rhodamine B (RhB) in the presence of H₂O₂ under visible light illumination.     

Synthesis and Characterization of Novel Biodegradable Polyamides Containing α-amino Acid

The polyamides were obtained from 1,6-hexanediamine and diacylchloride which incorporated α -amino acid residues through interfacial polycondensation. High molecular weight (η_inh = 1.05–1.18 dL/g) polymers were produced with high yields. The structure of polyamides was verified by FT-IR and ¹H NMR spectra. They showed a remarkable ability to develop high crystallinity with melting temperatures in the range 117–191°C and was stable up to 350°C under nitrogen. Two methods such as alkali hydrolysis (10% NaOH w/v, 80°C) and enzymatic hydrolysis were employed for assessing the susceptibility of these polyamides to degradation. A preliminary investigation of the 5-fluorouracil (5-FU) release characteristics of these polyamides showed that the release rate increased with increasing water absorption of the polymers.     

A New Type of Biomimetic Model: Design, Synthesis and Characterization of Imidazolium Bis-Estrogen

Biomimeticmoleculessuchasartificialenzpoesandreceptorshavebeenattractinggrowingattention[1].Duetosteroidalplanar,largeandrigidhydrophobicbackbone,anditsnaturalchiralsource,steroid-basedartificialbiomimeticmodelssuchasthebis-androgenandthebis-bileacidhavebeenspeciallyfOcused..[2-5]inrecentyears-HerewerePOrtforthefirsttimeonthedesignandsynthesisofimidazoliumbis-estrogens4a'basanewtyPeofbiomimeticmodel,whichPOssessPOtentialmLiltiplebiomimeticfunctions.Theschemeisout1inedasfollows.Themode1s4a'…     

Synthesis,Characterization and SOD Activities of IP-copper（Ⅱ）-L-amino Acid Complexes

Four new ternary complexes： [Cu（IP）（L-Val）（H2O）]ClO4·1.5H2O（1）, [Cu（IP）（L-Leu）（H2O）]ClO4（2）, [Cu（IP）（L-Tyr）（H2O）]ClO4·H2O（3） and [Cu（IP）（L-Trp）（H2O）]ClO4·1.5H2O（4） have been synthesized and character/zed by elementa/analysis, molar conductivity, infrared absorption spectroscopy, electronic absorption spectroscopy and cyclic voltammetry, where IP=imidazo[4,5-f][1,10] phenanthroline, L-Val=L-valinate, L-Leu=L-leucinate, L-Tyr=L-tyrosinate and L-Trp=L-tryptophanate. Complex 3 was structurally characterized by X-ray diffraction method, which crystallizes in orthorhornbic space group P21212 in a unit cell of dimensions a=3.0567（4） nm, b=0.74079（9） nm, c= 1.06198（13） nm, V=2.4047（5） nm^3, Z=4,μ=0.1084 cm^-1. The SOD-like activities of catalytic disrnutation of superoxide anions （O2^-· ） by the complexes were determined by means of modified nitroblue tetrazolium （NBT） photoreduction. The IC50 values of complexes 1, 2, 3 and 4 are 0.072, 0.147, 0.429 and 0.264 μmol·L^-1, respectively     

Synthesis and Characterization of Manganese Carbonyl Compounds with PNP

Attheendof1930s,ThesynthesisofMn(C6H6)21firstreportedbyH.Gilmanattractedmuchattention.Subsequently,manyneworgano-manganesecompoundshavebeensythesized.Inthe1950s,itwasfoundthatCPMn(CO)3andsomeofitSderivativesaughtactastheantiknockofgasolinetosubstitutetetra-ethylleadwhichisveryharmfultoourenvironment.Thisfindinghasattractedpeople'sinterestinthestudyofthisfield.Inthiswork,weobtainedtwonewcompoundsthroughthesubstitutionreactionbetweenmixeddonorphosphineligand2,6-di(hi-phenylphosphine)pyridme…     

Preparation and Characterization of Molybdotungstoniobogermanic Acid

Recently,thepreparationandpropertiesofheteropolycomplexeshaveincreasinglyattractedattentioninvariousfieldsofchendstIy,especiallyincatalysicapplicationsfortheiruniqueproperties'.Sincel988,thestudiesoffour-baseheteropolycomplexeswiththeKegginstructurehavebeenreported.Asthespecialbifunctionalcatalyticand.-lantisepsispropertyoftheheteropolycomplexescontainingniobium',andsofarthemolybdotungstoniobogermanicheteropolycomplexesinwhichthecentralatomisgermanium,havenotbeenreportedyet,ennea-tungsto-bi-mo…     

Synthesis, Characterization and the Effect of Glucose-lowering of Guanidino Acid Oxovanadium（Ⅳ） Complexes

Two guanidino acid oxovanadium(Ⅳ) complexes have been synthesized. Preliminary tests in vivo have shown that the two title complexes all display lowering glucose activity in vivo to STZ-rats. The effect of glucose-lowering of guanidino acetic acid oxovanadium(Ⅳ) complex in vivo is higher than that of guanidino propanoic acid oxovanadium(Ⅳ) complex.     

Hydrolysis of Cyclic Ureas under Microwave Irradiation: Synthesis and Characterization of 7,8‐Diaminopelargonic Acid

A simple and efficient method for the synthesis of 7,8‐diaminopelargonic acid, a key intermediate in the biotin biosynthesis pathway, is reported. The d‐desthiobiotin powder was dissolved in concentrated hydrochloric acid, and the solution was exposed to microwave radiation of 2.45 GHz for varying lengths of time ranging from 60 s to 2 min. The product thus obtained was characterized by spectroscopic techniques and confirmed through bioassay. Further, the protocol was extended to the synthesis of several diamines from their corresponding cyclic ureas. The results show that the method is generally applicable and not only accelerates the hydrolysis reaction but also offers excellent yields.     

Synthesis, Spectroscopic Properties and Crystal Structural Characterization of a Triphenyltin(Ⅳ) Complex with 5-Bromonicotinic Acid

A novel organotin complex [Ph3Sn(C2H5OH)(OCOC5H3NBr)SnPh3(OCOC5H3NBr)]has been synthesized by the reaction of 5-bromonicotinic acid with triphenyltin hydroxide in ethanol and characterized by elemental analysis, IR and 1H NMR. The crystal structure was determined by X-ray single-crystal diffraction. The crystal belongs to the monoclinic system, space group P21/c with a = 15.564(2), b = 24.975(4), c = 12.2973(19) (A), β = 92.224(2)°, Z = 4, V = 4776.5(13) (A)3, Dc = 1.596g/cm3, μ(MoKα) = 2.765 mm-1, F(000) = 2264, R = 0.0385 and wR = 0.0667. In the molecular structure of the title complex, the tin atoms are five-coordinated in a trigonal bipyramidal geometry.     

Synthesis,Spectroscopic Properties and Crystal Structural Characterization of a Triphenyltin(IV) Complex with 5-Bromonicotinic Acid

1 INTRODUCTION Organotin esters of carboxylic acids are widely used as biocides, fungicides and homogeneous ca- talysts in industry[1～3]. Recently, pharmaceutical pro- perties of organotin esters of carboxylic acids have been investigated for their antitumour activity[4, 5]. Studies on organotin compounds containing car- boxylate ligands with additional donor atoms (e.g. N, O or S) that are available for coordination to the tin atom have revealed that new structural types may lead to di…     

Synthesis and Characterization of Polymeric Acid‐Doped Polyaniline Interpenetrating Polymer Networks

Polyaniline (PANI)/poly(2‐acrylamido‐2‐methylpropane sulfonic acid) (PAMPS) semi‐interpenetrating network polymers (semi‐IPNs) were prepared using the simultaneous method. The formation and properties of the interpenetrating PANI/PAMPS semi‐IPNs were investigated using Fourier transform infrared spectroscopy, X‐ray diffraction, solid‐state ¹³C‐NMR, differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). The interaction of PAMPS with PANI as a polymeric acid dopant was also investigated. These semi‐IPNs had a different microstructure compared to that of pure PANI. Packing structures and several decomposition steps were ordered for each semi‐IPN, while pure PANI exhibits a single amorphous peak and one decomposition step. The NMR spectra show that these peaks broaden and shifted downfield in the semi‐IPNs. A thermal reaction between PANI and PAMPS was observed using DSC and TGA, and the data from the two techniques are in agreement.