共查询到20条相似文献,搜索用时 15 毫秒
1.
Zh. V. Bren' V. I. Usacheva G. D. Palui V. A. Bren' V. I. Minkin 《Chemistry of Heterocyclic Compounds》1977,13(5):498-502
The ionization constants of the conjugate acids of the reaction series 2-(N-arylaminomethylene)-3(2H)-benzo[b]thiophenones,-benzo[b]furanones, and -benzo[b]selenophenones were determined by potentiometric titration in anhydrous acetonitrile. The electronic and vibrational spectroscopic data showed that the protonation center in the molecules of these compounds is the carbonyl oxygen atom. It was established by correlation analysis that N-aryl substituents affect the protonation center primarily via an induction mechanism.Communication XVIII from the series Basicities and structures of azomethines and their structural analogs. See [1] for communication XVII.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. pp. 619–623, May, 1977. 相似文献
2.
以焦性没食子酸、4-羟基苯甲醛和酚为原料, 以邻碘代苯酚与苯乙炔衍生物的Sonogashira偶联及其连串化反应生成苯并呋喃环为关键步骤, 设计合成了一系列2-(2 ,6 -二烷氧基苯基)苯并呋喃衍生物, 并对产物进行了1H NMR, 13C NMR, MS等表征. 相似文献
3.
I. I. Chuev S. M. Aldoshin O. A. Kozina A. D. Dubonosov E. N. Shepelenko V. A. Bren' V. I. Minkin 《Russian Chemical Bulletin》1992,41(12):2230-2233
X-ray structural analysis was used to determine the molecular and crystal structure of 2-(N-benzyl-N-phenylhydrazinoethylidene)-3-(2H)-benzo[b]thiophenone. The crystals are monoclinic, the space group isC2/c,a=16.022(6),b=11.202(3),c=22.111(4) Å, =81.08(3)°, and andZ=8. It was shown that the ability of hydrazones of a similar class to exhibit photochromic properties is a function of the steric stresses in the molecules and their confirmation.Institute of Chemical Physics in Chernogolovka, Russian Academy of Sciences, 142432 Chernogolovka. Translated fromIzvestiya Akademii Nauk, Seriya Khimicheskaya, No. 12, pp. 2805–2809, December, 1992. 相似文献
4.
5.
V. P. Litvinov V. A. Petukhov V. Yu. Mortikov A. F. Vaisburg 《Chemistry of Heterocyclic Compounds》1986,22(6):608-612
A number of new selenolaldimines of benzo [b] furan were synthesized. It was established that they exist in dipolar form with delocalized multiple bonds.See [1] for communication 44.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 774–778, June, 1986. 相似文献
6.
Zusammenfassung Die Synthese der Titelverbindungen erfolgte über die Benzo[b]thiophen-3-essigsäure, deren Chlorid mit Diäthylamin und N-Methylpiperazin zu den entsprechenden N-substituierten Benzo[b]thiophen-3-acetamiden reagierte; diese wurden mit LiAlH4 zu tertiären Aminen reduziert.Die Synthese der homologen 2-Methylverbindungen ging vom 2-Methyl-3-acetyl-benzo[b]thiophen aus: Haloformreaktion gab 2-Methyl-benzo[b]thiophen-3-carbonsäure;Wolff-Umlagerung des entsprechenden Diazomethylketons in Gegenwart von sekundären Aminen lieferte verschiedene N-substituierte 2-Methyl-benzo[b]thiophen-3-acetamide, von denen drei mit LiAlH4 zu tertiären Aminen reduziert wurden.
The title substances were synthesized using benzo[b]thiophene-3-acetic acid as an intermediate, the acid chloride of which reacted with diethylamine and N-methylpiperazine to give the corresponding N-substituted benzo[b]thiophene-3-acetamides; these were reduced by LiAlH4 to tertiary amines.The synthesis of the homologous 2-methyl compounds started from 2-methyl-3-acetyl-benzo[b]thiophene: haloform reaction gave 2-methyl-benzo[b]thiophene-3-carboxylic acid;Wolff-rearrangement of the corresponding diazomethyl ketone in the presence of secondary amines yielded various N-substituted 2-methyl-benzo[b]thiophene-3-acetamides; three of them were reduced by LiAlH4 to tertiary amines.相似文献
7.
微波促进下3-(2-苯并呋喃基)-4-氨基-5-巯基-1,2,4-三唑 总被引:1,自引:0,他引:1
微波辐射条件下, 首先由2-苯并呋喃甲酰肼依次与二硫化碳和水合肼反应合成3-(2-苯并呋喃基)-4-氨基-5-巯基- 1,2,4-三唑, 进一步在微波辐射条件下由4-氨基-5-巯基-1,2,4-三唑分别与芳甲酸/芳氧基乙酸、α-溴代苯乙酮及芳醛反应以较高产率制得了相应的1,2,4-三唑并[3,4-b]-1,3,4-噻二唑、1,2,4-三唑并[3,4-b]-1,3,4-噻二嗪及4-芳亚甲基亚胺基-5-巯基-1,2,4-三唑. 产物结构经IR, 1H NMR, MS及元素分析进行了表征. 相似文献
8.
Zusammenfassung Bromierung von 2-Methyl-3-acetyl-benzo[b]thiophen ergab 2-Methyl-3-bromacetyl-benzo[b]thiophen, das beim Umsetzen mit Dimethylamin, Morpholin und N-Methylpiperazin die entsprechend basisch substituierten 3-Acetylverbindungen lieferte. Diese wurden mit LiAlH4 zu den -Hydroxyverbindungen reduziert.In ähnlicher Weise wurde auch 3-Diäthylaminoacetyl-benzo[b]thiophen dargestellt.
Bromination of 2-methyl-3-acetyl-benzo[b]thiophene gave 2-methyl-3-bromacetyl-benzo[b]thiophene, which reacted with dimethylamine, morpholine and N-methylpiperazine to give the corresponding base-substituted 3-acetyl derivatives. These were reduced by LiAlH4 to the -hydroxy compounds.Similarily 3-diethylaminoacetyl-benzo[b]thiophene was synthesized.相似文献
9.
S. M. Aldoshin L. O. Atovmyan R. F. Trofimova V. A. Bren' V. P. Rybalkin A. é. Lyubarskaya V. I. Minkin 《Russian Chemical Bulletin》1989,38(7):1412-1416
Conclusions It was established by x-ray crystallographic investigation that the inhibition of the photochromism of the nitro derivative (IIb) compared with compounds (I) and (IIa) is due to the difference in the structure of the molecules and to the realization of the low-lying triplet n* state, due to the presence of the p-nitro group. The flattening of the p-nitrobenzoyl fragment and its rotation from the plane of the molecule evidently promote localization of the photoexcitation energy in this conjugated fragment of the molecule and lead to nonradiative deactivation of the excited S1* state by intercombination conversion through the n triplet state and, finally, to a marked decrease in the yields of the fluorescence and the phototransformations.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 7, pp. 1544–1548, July, 1989.The authors are grateful to M. I. Knyazhanskii for assistance in the discussion of the results. 相似文献
10.
11.
Electronic, IR and UV spectroscopy has shown that 2-(N-isatinomethylene)-3(2H)-benzo[b]thiophenone in solution displays photo- and solvatochromism as a result of reversible E Z isomerization, and it readily undergoes alcoholysis of the lactam bond. The resulting aminovinyl ketones exist as mixtures of the thermodynamically stable E- and Z-isomers.For Communication 45, see [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1217–1220, September, 1989. 相似文献
12.
E. N. Shepelenko V. A. Bren' G. E. Andreichkova 《Chemistry of Heterocyclic Compounds》1987,23(8):833-836
Some 2-benzoyl-3-alkoxybenzo[b]thiophenones, 2-[N-aryl(alkyl)aminobenzylidene]-3(2H)-benzo[b]thiophenones, and their N-formyl derivatives have been synthesized. According to their UV, IR, and PMR spectra, these have the aminobenzylideneketone structure.For Communication 39, see [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1043–1046, August, 1987. 相似文献
13.
Hitoshi Takeshita Hiroaki Mametsuka Hideshi Motomura 《Journal of heterocyclic chemistry》1986,23(4):1211-1214
Upon heating at ca. 160°, 2-(2-thienylmethoxy)tropone afforded 3- and 5(2-thienylmethyl)tropolones. Formation of 3,5-bis(2-thienylmethyl)tropolone and unsubstituted tropolone indicated a radical chain mechanism for the thermolysis. 相似文献
14.
Mukunda R. Patekar Vijay J. Medhane Ghanshyam J. Jadhav Mayur J. Thakare Dattatray G. Deshmukh 《Journal of heterocyclic chemistry》2021,58(11):2152-2162
A new series of (s)-1-{3-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmetyl}-3-substituted-urea derivatives have been synthesized and characterized with spectral data, such as IR, NMR and Mass spectroscopies. All compounds are in vitro evaluated for their efficacy as antimicrobial agent against the gram-positive pathogenic strains such as Bacillus subtilis ATCC 6633, Staphylococcus aureus ATCC 25923, Staphylococcus epidermidis ATCC 12228 and Streptococcus pyogens ATCC 8668. Five compounds ( 19k , 19l , 19m , 19n and 19o ) out of 15 compounds showed moderate activity. 相似文献
15.
L. T. Kaulinya L. M. Yagupol'skii N. V. Kondratenko E. P. Vechirko A. É. Berzlnya V. N. Silinya É. É. Liepin'sh M. Yu. Lidak R. A. Zhuk 《Chemistry of Heterocyclic Compounds》1982,18(2):202-205
The synthesis of 2-fluoromethyltetrahydrofuran is described, and it is shown that chlorination of the latter gives 2-chloro-5- and 2-chloro-2-fluoromethyltetrahydrofurans in a ratio of 5:1. 2,4-Bis(trimethylsilyl) derivatives of uracil were alkylated by means of the mixture of -chloro ethers without separation, and a mixture of the cis and trans isomers of 1-(5-fluoromethyltetrahydro-2-furyl)uracils and 1-(2-fluoromethyltetrahydro-2-furyl)uracils were obtained. The reaction products were identified on the basis of the PMR spectra.See [1] for communication 16.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 256–259, February, 1982. 相似文献
16.
Drzewiecka Aleksandra Koziol Anna E. Pena Ruiz Tomas Fernandez Gomez Manuel Struga Marta Kossakowski Jerzy Ostrowska Kinga Lis Tadeusz 《Structural chemistry》2012,23(5):1617-1629
Structural Chemistry - The selected derivatives of the 2- and 3-benzo[b]furancarboxylic acids were synthesized and their structures were studied using the X-ray crystallography and the... 相似文献
17.
18.
David B. Repke Wilfred J. Ferguson Dallas K. Bates 《Journal of heterocyclic chemistry》1977,14(1):71-74
The synthesis of four dialkyl and three eyeloalkyl analogs of psilocin (4, R - CH3), a hallucinogenic principle found in certain fungi, is described. The synthetic route involves four transformations starting with 6,7-dihydroindol-4(5H)one: (1). 相似文献
19.
I. I. Chuev S. M. Aldoshin V. A. Bren' E. N. Shepelenko 《Russian Chemical Bulletin》1995,44(1):99-101
An X-ray investigation of 2-(N,N-diphenylhydrazinoethylidene)-3(2H)-benzo[b]thiophenone was performed at room and low (–80 °C) temperatures. It was established that the structure of this compound in the crystalline state at R-20 °C is intermediate between the ketoenehydrazine and hydroxyhydrazone forms, while at –80 °C the molecular structure is completely transformed to the hydroxyhydrazone form. This confirms the dynamic nature of hydrogen atom disordering in the molecule at 20 °C.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 104–106, January, 1995.This work was financially supported by the Russian Foundation for Basic Research (Project No. 93-03-04355). 相似文献