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1.
Cassandra D. Engeman Lynn Baumgartner Benjamin M. Carr Allison M. Fish John D. Meyerhofer Terre A. Satterfield Patricia A. Holden Barbara Herr Harthorn 《Journal of nanoparticle research》2012,14(3):749
Current research on the nanotechnology industry indicates its downstream expansion at a rapid pace, while toxicological research
and best practices for environmental health and safety are still being developed. Companies that use and/or produce engineered
nanomaterials (ENMs) have enormous potential to influence safe-handling practices for ENMs across the product life cycle.
Knowledge of both industry practices and leaders’ perceptions of risk is vital for understanding how companies will act to
control potential environmental and health risks. This article reports results from a new international survey of nanomaterials
companies in 14 countries. In this survey, company participants reported relatively high levels of uncertainty and/or perceived
risk with regard to ENMs. However, these perspectives were not accompanied by expected risk-avoidant practices or preferences
for regulatory oversight. A majority of companies indicated “lack of information” as a significant impediment to implementing
nano-specific safety practices, but they also reported practices that were inconsistent with widely available guidance. Additionally,
in the absence of safe-handling regulations, companies reported nano-specific health and safety programs that were narrow
in scope. Taken together, these findings indicate that health and safety guidance is not reaching industry. While industry
leaders’ reluctance toward regulation might be expected, their own reported unsafe practices and recognition of possible risks
suggest a more top-down approach from regulators is needed to protect workers and the environment. 相似文献
2.
Jing Wang Christof Asbach Heinz Fissan Tim Hülser Thomas A. J. Kuhlbusch Drew Thompson David Y. H. Pui 《Journal of nanoparticle research》2011,13(4):1373-1387
Nanotechnology has great potential to transform science and industry in the fields of energy, material, environment, and medicine.
At the same time, more concerns are being raised about the occupational health and safety of nanomaterials in the workplace
and the implications of nanotechnology on the environment and living systems. Studies on environmental, health, and safety
(EHS) issues of nanomaterials have a strong influence on public acceptance of nanotechnology and, eventually, affect its sustainability.
Oversight and regulation by government agencies and non-governmental organizations (NGOs) play significant roles in ensuring
responsible and environmentally friendly development of nanotechnology. The EHS studies of nanomaterials can provide data
and information to help the development of regulations and guidelines. We present research results on three aspects of EHS
studies: physico-chemical characterization and measurement of nanomaterials; emission, exposure, and toxicity of nanomaterials;
and control and abatement of nanomaterial releases using filtration technology. Measurement of nanoparticle agglomerates using
a newly developed instrument, the Universal NanoParticle Analyzer (UNPA), is discussed. Exposure measurement results for silicon
nanoparticles in a pilot scale production plant are presented, as well as exposure measurement and toxicity study of carbon
nanotubes (CNTs). Filtration studies of nanoparticle agglomerates are also presented as an example of emission control methods. 相似文献
3.
Nanomedicine is a relatively new field of science and technology. It looks sometimes ill defined and interpretations of that term may vary, especially between Europe and the United States.By interacting with biological molecules, therefore at nanoscale, nanotechnology opens up a vast field of research and application. Interactions between artificial molecular assemblies or nanodevices and biomolecules can be understood both in the extracellular medium and inside the human cells. Operating at nanoscale allows to exploit physical properties different from those observed at microscale such as the volume/surface ratio.The investigated diagnostic applications can be considered for in vitro as well as for in vivo diagnosis. In vitro, the synthesised particles and manipulation or detection devices allow for the recognition, capture, and concentration of biomolecules. In vivo, the synthetic molecular assemblies are mainly designed as a contrast agent for imaging.A second area exhibiting a strong development is “nanodrugs” where nanoparticles are designed for targeted drug delivery. The use of such carriers improves the drug biodistribution, targeting active molecules to diseased tissues while protecting healthy tissue.A third area of application is regenerative medicine where nanotechnology allows developing biocompatible materials which support growth of cells used in cell therapy.The application of nanotechnology to medicine raises new issues because of new uses they allow, for instance: Is the power of these new diagnostics manageable by the medical profession? What means treating a patient without any clinical signs? Nanomedicine can contribute to the development of a personalised medicine both for diagnosis and therapy.There exists in many countries existing regulatory frameworks addressing the basic rules of safety and effectiveness of nanotechnology based medicine, whether molecular assemblies or medical devices. However, there is a need to clarify or to modify these regulations which mobilise many experts.France is a country where the medical development of nanotechnology is significant, like Germany, the United Kingdom or Spain, as regards the European Union. There is an active scientific community and industrial partners of all sizes, even if the technology transfer to industry is not as effective as in North America. 相似文献
4.
This article analyzes nanotechnology as an experiment in democratic deliberation, one that seems motivated both by a desire
to improve deliberative democracy and to protect the technology from undue public interference. However, rather than involving
amplified (overstated) risks, nanotechnology appears to involve attenuated (understated) risks. Results from a 3-year panel
study are presented to illustrate the ways in which citizens form opinions about nanotechnology, supporting the assertion
that public opinion about complex technology can be both reasonable and stable. Nevertheless, the authors also voice concern
that, in the absence of public pressure, risk regulation may not evolve as swiftly as it should to protect both society and
industry. 相似文献
5.
David M. Berube Christopher L. Cummings Jordan H. Frith Andrew R. Binder Robert Oldendick 《Journal of nanoparticle research》2011,13(8):3089-3099
Over the last decade social scientific researchers have examined how the public perceives risks associated with nanotechnology.
The body of literature that has emerged has been methodologically diverse. The findings have confirmed that some publics perceive
nanotechnology as riskier than others, experts feel nanotechnology is less risky than the public does, and despite risks the
public is optimistic about nanotechnology development. However, the extant literature on nanotechnology and risk suffers from
sometimes widely divergent findings and has failed to provide a detailed picture of how the public actually feels about nanotechnology
risks when compared to other risks. This study addresses the deficiencies in the literature by providing a comparative approach
to gauging nanotechnology risks. The findings show that the public does not fear nanotechnology compared to other risks. Out
of 24 risks presented to the participants, nanotechnology ranked 19th in terms of overall risk and 20th in terms of “high
risk.” 相似文献
6.
Vrishali Subramanian Elena Semenzin Danail Hristozov Alex Zabeo Ineke Malsch Eamonn McAlea Finbarr Murphy Martin Mullins Toon van Harmelen Tom Ligthart Igor Linkov Antonio Marcomini 《Journal of nanoparticle research》2016,18(4):89
The significant uncertainties associated with the (eco)toxicological risks of engineered nanomaterials pose challenges to the development of nano-enabled products toward greatest possible societal benefit. This paper argues for the use of risk governance approaches to manage nanotechnology risks and sustainability, and considers the links between these concepts. Further, seven risk assessment and management criteria relevant to risk governance are defined: (a) life cycle thinking, (b) triple bottom line, (c) inclusion of stakeholders, (d) risk management, (e) benefit–risk assessment, (f) consideration of uncertainty, and (g) adaptive response. These criteria are used to compare five well-developed nanotechnology frameworks: International Risk Governance Council framework, Comprehensive Environmental Assessment, Streaming Life Cycle Risk Assessment, Certifiable Nanospecific Risk Management and Monitoring System and LICARA NanoSCAN. A Sustainable Nanotechnology Decision Support System (SUNDS) is proposed to better address current nanotechnology risk assessment and management needs, and makes. Stakeholder needs were solicited for further SUNDS enhancement through a stakeholder workshop that included representatives from regulatory, industry and insurance sectors. Workshop participants expressed the need for the wider adoption of sustainability assessment methods and tools for designing greener nanomaterials. 相似文献
7.
8.
This paper presents the development of nanotechnology between 2000 and 2016 as reflected in the Web of Science papers, United States Patent and Trademark Office (USPTO), World International Property Organization (WIPO) patents, and National Science Foundation (NSF) awards, with a special reference to the United States (US), European Union (EU27), P.R. China, Japan, and South Korea. The field of nanotechnology is branching out into novel scientific and technology platforms, and it is increasingly difficult to separate foundational nanoscale components from divergent application areas. The average global growth rate has been sustained at about 15% for both papers and patents in the selected interval. The growth rates among regions are non-uniform. P.R. China and South Korea have increased faster in both the numbers and quality of their scientific publications, and currently P.R. China has the largest volume of nanotechnology publications and South Korea the most publications per capita in the field of nanotechnology. The US, EU27, and Japan are maintaining leadership in the upstream, better cited, conceptual components of nanotechnology research and development. 相似文献
9.
Longitudinal Nanotechnology Development (1991--2002): National Science Foundation Funding and its Impact on Patents 总被引:3,自引:3,他引:0
Zan Huang Hsinchun Chen Lijun Yan Mihail C. Roco 《Journal of nanoparticle research》2005,7(4-5):343-376
Nanotechnology holds the promise to revolutionize a wide range of products, processes and applications. It is recognized by over sixty countries as critical for their development at the beginning of the 21st century. A significant public investment of over $1 billion annually is devoted to nanotechnology research in the United States. This paper provides an analysis of the National Science Foundation (NSF) funding of nanoscale science and engineering (NSE) and its relationship to the innovation as reflected in the United States Patent and Trade Office (USPTO) patent data. Using a combination of bibliometric analysis and visualization tools, we have identified several general trends, the key players, and the evolution of technology topics in the NSF funding and commercial patenting activities. This study documents the rapid growth of innovation in the field of nanotechnology and its correlation to funding. Statistical analysis shows that the NSF-funded researchers and their patents have higher impact factors than other private and publicly funded reference groups. This suggests the importance of fundamental research on nanotechnology development. The number of cites per NSF-funded inventor is about 10 as compared to 2 for all inventors of NSE-related patents recorded at USPTO, and the corresponding Authority Score is 20 as compared to 1.8. 相似文献
10.
Nanotechnology and the need for risk governance 总被引:10,自引:0,他引:10
After identifying the main characteristics and prospects of nanotechnology as an emerging technology, the paper presents the general risks associated with nanotechnology applications and the deficits of the risk governance process today, concluding with recommendations to governments, industry, international organizations and other stakeholders. The International Risk Governance Council (IRGC) has identified a governance gap between the requirements pertaining to the nano- rather than the micro-/macro- technologies. The novel attributes of nanotechnology demand different routes for risk-benefit assessment and risk management, and at present, nanotechnology innovation proceeds ahead of the policy and regulatory environment. In the shorter term, the governance gap is significant for those passive nanostructures that are currently in production and have high exposure rates; and is especially significant for the several ‘active’ nanoscale structures and nanosystems that we can expect to be on the market in the near future. Active nanoscale structures and nanosystems have the potential to affect not only human health and the environment but also aspects of social lifestyle, human identity and cultural values. The main recommendations of the report deal with selected higher risk nanotechnology applications, short- and long-term issues, and global models for nanotechnology governance. 相似文献
11.
We report data from the first representative national phone survey of Americans' perceptions about nanotechnology (N =1536). Public opinion about nanotechnology is in its infancy, and knowledge about it is quite limited. Yet, Americans' initial reaction to nanotechnology is thus far generally positive, probably rooted in a generally positive view of science overall. Survey respondents expected benefits of nanotechnology to be more prevalent than risks, and they reported feeling hopeful about nanotechnology rather than worried. Their most preferred potential benefit of nanotechnology is new and better ways to detect and treat human diseases, and they identified losing personal privacy to tiny new surveillance devices as the most important potential risk to avoid. The most discouraging aspect to the data is respondents' lack of trust in business leaders to minimize nanotechnology risks to human health. Overall, these data indicate that while Americans do not necessarily presume benefits and the absence of risks, their outlook is much more positive than not. 相似文献
12.
John M. Balbus Karen Florini Richard A. Denison Scott A. Walsh 《Journal of nanoparticle research》2007,9(1):11-22
Nanotechnology, the design and manipulation of materials at the atomic scale, may well revolutionize many of the ways our
society manufactures products, produces energy, and treats diseases. New materials based on nanotechnology are already reaching
the market in a wide variety of consumer products. Some of the observed properties of nanomaterials call into question the
adequacy of current methods for determining hazard and exposure and for controlling resulting risks. Given the limitations
of existing regulatory tools and policies, we believe two distinct kinds of initiatives are needed: first, a major increase
in the federal investment in nanomaterial risk research; second, rapid development and implementation of voluntary standards
of care pending development of adequate regulatory safeguards in the longer term. Several voluntary programs are currently
at various stages of evolution, though the eventual outputs of each of these are still far from clear. Ultimately, effective
regulatory safeguards are necessary to provide a level playing field for industry while adequately protecting human health
and the environment. This paper reviews the existing toxicological literature on nanomaterials, outlines and analyzes the
current regulatory framework, and provides our recommendations, as an environmental non-profit organization, for safe nanotechnology
development. 相似文献
13.
Shirley S. Ho Dietram A. Scheufele Elizabeth A. Corley 《Journal of nanoparticle research》2010,12(8):2703-2715
Using a nationally representative telephone survey of 1,015 adults in the United States, this study examines how value predispositions, communication variables, and perceptions of risks and benefits are associated with public support for federal funding of nanotechnology. Our findings show that highly religious individuals were less supportive of funding of nanotech than less religious individuals, whereas individuals who held a high deference for scientific authority were more supportive of funding of the emerging technology than those low in deference. Mass media use and elaborative processing of scientific news were positively associated with public support for funding, whereas factual scientific knowledge had no significant association with policy choices. The findings suggest that thinking about and reflecting upon scientific news promote better understanding of the scientific world and may provide a more sophisticated cognitive structure for the public to form opinions about nanotech than factual scientific knowledge. Finally, heuristic cues including trust in scientists and perceived risks and benefits of nanotech were found to be associated with public support for nanotech funding. We conclude with policy implications that will be useful for policymakers and science communication practitioners. 相似文献
14.
Longitudinal Patent Analysis for Nanoscale Science and Engineering: Country,Institution and Technology Field 总被引:13,自引:6,他引:7
Huang Zan Chen Hsinchun Yip Alan Ng Gavin Guo Fei Chen Zhi-Kai Roco Mihail C. 《Journal of nanoparticle research》2003,5(3-4):333-363
Nanoscale science and engineering (NSE) and related areas have seen rapid growth in recent years. The speed and scope of development in the field have made it essential for researchers to be informed on the progress across different laboratories, companies, industries and countries. In this project, we experimented with several analysis and visualization techniques on NSE-related United States patent documents to support various knowledge tasks. This paper presents results on the basic analysis of nanotechnology patents between 1976 and 2002, content map analysis and citation network analysis. The data have been obtained on individual countries, institutions and technology fields. The top 10 countries with the largest number of nanotechnology patents are the United States, Japan, France, the United Kingdom, Taiwan, Korea, the Netherlands, Switzerland, Italy and Australia. The fastest growth in the last 5 years has been in chemical and pharmaceutical fields, followed by semiconductor devices. The results demonstrate potential of information-based discovery and visualization technologies to capture knowledge regarding nanotechnology performance, transfer of knowledge and trends of development through analyzing the patent documents. 相似文献
15.
Li Xin Chen Hsinchun Dang Yan Lin Yiling Larson Catherine A. Roco Mihail C. 《Journal of nanoparticle research》2008,10(1):3-22
Nanotechnology research and applications have experienced rapid growth in recent years. We assessed the status of nanotechnology research worldwide by applying bibliographic, content map, and citation network analysis to a data set of about 200,000 nanotechnology papers published in the Thomson Science Citation Index Expanded database (SCI) from 1976 to 2004. This longitudinal study shows a quasi-exponential growth of nanotechnology articles with an average annual growth rate of 20.7% after 1991. The United States had the largest contribution of nanotechnology research and China and Korea had the fastest growth rates. The largest institutional contributions were from the Chinese Academy of Sciences and the Russian Academy of Sciences. The high-impact papers generally described tools, theories, technologies, perspectives, and overviews of nanotechnology. From the top 20 institutions, based on the average number of paper citations in 1976–2004, 17 were in the Unites States, 2 in France and 1 in Germany. Content map analysis identified the evolution of the major topics researched from 1976 to 2004, including investigative tools, physical phenomena, and experiment environments. Both the country citation network and the institution citation network had relatively high clustering, indicating the existence of citation communities in the two networks, and specific patterns in forming citation communities. The United States, Germany, Japan, and China were major citation centers in nanotechnology research with close inter-citation relationships. 相似文献
16.
Vladimir Murashov Stefan Engel Kai Savolainen Brian Fullam Michelle Lee Peter Kearns 《Journal of nanoparticle research》2009,11(7):1587-1591
The Organization for Economic Cooperation and Development (OECD), an intergovernmental organization, is playing a critical
global role in ensuring that emerging technologies, such as nanotechnology, are developed responsibly. This article describes
OECD activities around occupational safety and health of nanotechnology and provides state-of-the-science overview resulting
from an OECD workshop on exposure assessment and mitigation for nanotechnology workplace. 相似文献
17.
Public Attitudes Toward Nanotechnology 总被引:5,自引:5,他引:0
Data from 3909 respondents to an Internet survey questionnaire provide the first insights into public perceptions of nanotechnology. Quantitative analysis of statistics about agreement and disagreement with two statements, one positive and the other negative, reveals high levels of enthusiasm for the potential benefits of nanotechnology and little concern about possible dangers. The respondents mentally connect nanotechnology with the space program, nuclear power, and cloning research, but rate it more favorably. In contrast, they do not associate nanotechnology with pseudoscience, despite its imaginative exploitation by science fiction writers. Qualitative analysis of written comments from 598 respondents indicates that many ideas about the value of nanotechnology have entered popular culture, and it provides material for an additional 108 questionnaire items that can be used in future surveys on the topic. The findings of this exploratory study can serve as benchmarks against which to compare results of future research on the evolving status of nanotechnology in society. 相似文献
18.
Parvin Farshchi Seyed Khatiboleslam Sadrnezhaad Naser Moharram Nejad Mahmood Mahmoodi Leila Ibrahimi Ghavam Abadi 《Journal of nanoparticle research》2011,13(8):3511-3519
Using survey data, public awareness of and attitudes toward nanotechnology are examined in Iran (N = 759). Iran is a developing country with a national nanotechnology action plan for a ten year period starting from 2003
and has been active in the field of research and development of nanotechnology meanwhile. First, the results show that majority
of people are still not familiar with nanotechnology and perceived risks posed by this technology are not considered to be
a lot and most people feel its benefits outweigh the risks. The emotions toward this technology are of a hopeful and positive
nature and this technology is looked upon favorably in Iran. In particular, our results reveals that although the level of
trust is high specially in scientists to communicate the risks with the public, there are a great number who just have some
trust not quite a lot of it. Knowing that it is a hard and time-consuming effort to manage a nation’s view on nanotechnology,
extensive research as well as collaboration with other countries is needed to effectively communicate the risks in time. 相似文献
19.
Ashley A. Anderson Dominique Brossard Dietram A. Scheufele 《Journal of nanoparticle research》2010,12(4):1083-1094
The shift toward online communication in all realms, from print newspapers to broadcast television, has implications for how
the general public consumes information about nanotechnology. The goal of this study is threefold: to investigate who is using
online sources for information and news about science and nanotechnology, to examine what the general public is searching
for online with regards to nanotechnology, and to analyze what they find in online content of nanotechnology. Using survey
data, we find those who report the Internet as their primary source of science and technology news are diverse in age, more
knowledgeable about science and nanotechnology, highly educated, male, and more diverse racially than users of other media.
In a comparison of demographic data on actual visits by online users to general news and science Web sites, science sites
attracted more male, non-white users from the Western region of the United States than news sites did. News sites, on the
other hand, attracted those with a slightly higher level of education. Our analysis of published estimates of keyword searches
on nanotechnology reveals people are turning to the Internet to search for keyword searches related to the future, health,
and applications of nanotechnology. A content analysis of online content reveals health content dominates overall. Comparisons
of content in different types of sites—blogs, government, and general sites—are conducted. 相似文献
20.
As governments around the world begin to implement regulations aimed at controlling nanotechnology, those regulations should
be based upon the best available science, applied as consistently as possible within jurisdictions and, to the extent feasible,
across jurisdictions. These goals would be easier to achieve with the creation of an international nanoscience advisory board.
Such a body could be modeled on similar international scientific advisory bodies for other issues, such as the Intergovernmental
Panel on Climate Change (IPCC) and the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services. Such
a body should also take into account lessons learned from these similar organizations. An international nanoscience advisory
board could assist regulatory bodies by providing a central source of accurate scientific information about the risks and
benefits of nanotechnology, including relevant uncertainties, rather than having each regulatory body make these determinations
independently. An international nanoscience advisory board could facilitate harmonization within and between jurisdictions
by involving the top experts in the field to produce a centralized knowledge base for regulatory decisions. While an international
nanoscience advisory board presents many potential benefits, it also faces significant difficulties, which are best illustrated
by examining the history and challenges of existing international science advisory bodies. 相似文献