共查询到20条相似文献,搜索用时 31 毫秒
1.
Mohammad Anary-Abbasinejad Fereshteh Nejad-Shahrokhabadi 《Phosphorus, sulfur, and silicon and the related elements》2020,195(8):660-665
AbstractA three-component reaction between barbituric/thiobarbituric acid, phosphines, and dialkyl acetylenedicarboxylates in dry acetonitrile led to the formation of barbiturate/thiobarbiturate-functionalized stable zwitterionic salts in a one-pot process. When trialkyl phosphites were used instead of phosphines, barbiturate/thiobarbiturate-functionalized phosphonates were obtained in good yields. 相似文献
2.
V. A. Kuropatov V. K. Cherkasov G. K. Fukin G. A. Abakumov 《Russian Chemical Bulletin》2011,60(11):2291-2295
A reaction of 3,6-di(tert-butyl)-4-chloro-1,2-benzoquinone with disubstituted N,N-dithiocarbamates leads to zwitterionic compounds containing 2-iminio-1,3-dithiole ring annulated to the quinone skeleton. These products reversibly add acids, giving salts of the corresponding catechols; they form complexes with copper involving oxygen atoms, as well. 相似文献
3.
T.S. Khlebnicova V.G. Isakova A.V. Baranovsky E.V. Borisov F.A. Lakhvich 《Journal of fluorine chemistry》2006,127(12):1564-1569
A one-pot synthesis of 2-perfluoroalkanoylcyclohexane-1,3-diones via C-acylation of cyclohexane-1,3-diones with N-perfluoroacylimidazole as an acylating agent is reported. A reaction was examined with isolated N-trifluoroacetylimidazole and with N-perfluoroacylimidazoles generated in situ from perfluorocarboxylic acid anhydrides or perfluorocarboxylic acids. 相似文献
4.
Shapi A. Siddiqui 《Tetrahedron》2005,61(14):3539-3546
An improved and rapid one-pot synthesis of 2,4,5-triaryl imidazoles in a room temperature ionic liquid is described, which does not need any added catalyst. Different ionic liquids based on 1-n-butyl and 1,3-di-n-butyl imidazolium salts were screened and their efficacy in terms of acidity and polarity have been correlated with yields and reaction period. The one-pot methodology resulting in excellent isolated yields in short reaction times is characterized by simple work up procedures and efficient recovery and recycling of the ionic liquid, which acts as a promoter. 相似文献
5.
A new one-pot synthesis of 1,3-aminols by direct reduction of β-enamino ketones, formed in situ by reaction of easily available β-dicarbonyl compounds, with anilines were described. In the case of aliphatic amines such as benzyl amine, n-butyl amine and β-hydroxy ethyl amine, the corresponding 1,3-minols were not obtained. In fact, the β-enamino ketone formed was failed to accomplish further reduction to 1,3-aminol. This approach is the most direct available method for the synthesis of 1,3-aminols. 相似文献
6.
Ahmad Shaabani Mozhdeh Seyyedhamzeh Ali Maleki Maryam Behnam Fahimeh Rezazadeh 《Tetrahedron letters》2009,50(24):2911-4167
A one-pot four-component reaction of an aliphatic or aromatic amine, diketene, an aromatic aldehyde and 1,3-diphenyl-1H-pyrazol-5-amine in the presence of p-toluenesulfonic acid as a catalyst has been developed. In this reaction, a new class of fully substituted pyrazolo[3,4-b]pyridine-5-carboxamide derivatives is produced under mild reaction conditions and in good yields at ambient temperature. 相似文献
7.
A one-pot three-component process for the synthesis of highly functionalized 2,3-dihydrofurans from 1,3-dicarbonyl compounds, aromatic aldehydes, and N-phenacylpyridinium bromides has been developed. Benzylidene 1,3-dicarbonyl compounds could be generated in situ from aromatic aldehydes and 1,3-dicarbonyl compounds and then reacted smoothly with N-phenacylpyridinium bromides to produce 2,3-dihydrofurans in moderate to good yields. Piperidine/acetonitrile is the optimal condition for this process. To increase the efficiency of this reaction, this one-pot process was also conducted solvent-free under classical heating conditions and grinding conditions. 相似文献
8.
Recyclable ionic Brönsted acid was prepared in nearly quantitative yield by reacting 1-butylimidazole with an equimolar amount of 1,3-propanesultone, followed by treatment with an equimolar amount of trifluoromethanesulfonic acid. The ionic Brönsted acid-catalyzed direct benzylation, allylation and propargylation of 1,3-dicarbonyl compounds with various alcohols in ionic liquid [N-ethyl-N-methyl imidazolium trifluoromethanesulfonate (EMIOTf)], at 100 °C for 3 h proceeded smoothly to give the corresponding products in good to excellent yields without the use of any hazardous or volatile solvents and without any by-product such as salts. Furthermore, tandem benzylation-cyclization-dehydration of 1,3-dicarbonyl compounds to give functionalized 4H-chromenes was also achieved in this catalytic reaction. 相似文献
9.
F. Matloubi Moghaddam H. Saeidian Z. Mirjafary A. Sadeghi 《Journal of the Iranian Chemical Society》2009,6(2):317-324
A one-pot four-component reaction of aldehydes, ethyl acetoacetate/5,5-dimethyl-1,3-cyclohexanedione, ethyl acetoacetate and ammonium acetate in the presence of 10 mol% of ZnO as a heterogeneous catalyst for the synthesis of corresponding 1,4- dihydropyridine and polyhydroquinoline derivatives via the Hantzsch condensation is described. The present methodology offers several advantages such as simple procedure, excellent yields, and short reaction time. 相似文献
10.
Mazaahir Kidwai Anwar Jahan Ritika Chauhan Neeraj Kumar Mishra 《Tetrahedron letters》2012,53(14):1728-1731
A new green protocol has been developed for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones via one-pot, three-component condensation reaction of aromatic aldehydes with 1,3-dicarbonyl compounds and phthalhydrazide using reusable dodecylphosphonic acid (DPA) as heterogeneous solid acid catalyst under solvent-free conditions. This protocol provides a novel and improved method for obtaining 2H-indazolo[2,1-b]phthalazine-triones in terms of good yields with little catalyst loading. 相似文献
11.
A simple, efficient procedure for the preparation of phospho sulfonic acid PO(OSO3H)3 as a Brønsted acidic and recoverable heterogeneous catalyst is described, used for the one-pot synthesis of aryl-14H-dibenzo[a,j]xanthenes and 1,8-dioxo-octahydro-xanthenes. A cost-effective, simple and convenient procedure for the synthesis of aryl-14H-dibenzo[a,j]xanthenes was developed via a one-pot condensation from substituted benzaldehydes and β-naphthol under solvent-free conditions. The one-pot condensation of substituted benzaldehydes and 5,5-dimethyl-1,3-cyclohexanedione (dimedone) under solvent-free conditions leads to 1,8-dioxo-octahydro-xanthenes. These protocols afford a number of advantages, such as: excellent yields, very short reaction times, easy procedure, simple methodology and ease of preparation and regeneration of the catalyst. 相似文献
12.
Aleksandra Minić Jovana P. Bugarinović Anka Pejović Danijela Ilić Komatina Goran A. Bogdanović Ivan Damljanović Dragana Stevanović 《Tetrahedron letters》2018,59(38):3499-3502
A simple one-pot synthesis of new ferrocene-containing 1,3-thiazinan-2-imines from 3-arylamino-1-ferrocenylpropan-1-ols and phenyl isothiocyanate has been developed. The key intermediate β-hydroxy thioureas were generated in situ using ultrasound irradiation and subsequent cyclization was achieved by the addition of acetic acid. The scope of the reaction towards various 3-arylamino-1-ferrocenylpropan-1-ols has been explored and the corresponding 3-aryl-6-ferrocenyl-N-phenyl-1,3-thiazinan-2-imines were obtained in moderate to high yields (52–90%). 相似文献
13.
A simple synthesis of 2-(alkylamino)-5-{alkyl[(2-oxo-2H-chromen-3-yl)carbonyl]amino}-3,4-furandicarboxylates via a one-pot multi-component reaction is described. The reactive 1:1 zwitterionic intermediate generated from the addition of isocyanides to dialkyl acetylenedicarboxylates was trapped at room temperature by coumarin-3-carboxylic acids prepared in situ from a 2-hydroxy aromatic aldehyde and Meldrum’s acid to afford the title compounds in good to excellent yields. 相似文献
14.
Maksim V. Dmitriev Tatyana V. Salnikova Pavel S. Silaichev Andrey N. Maslivets 《Tetrahedron letters》2017,58(1):67-70
A new methodology for the synthesis of spiro[indeno[1,2-b]quinoline-10,3′-pyrrole] derivatives via a Hantzsch-type reaction has been developed. This process involves the one-pot, three-component reaction of a 1H-pyrrole-2,3-dione, an aminocyclohexenone and 1,3-indanedione in acetic acid at reflux. Operationally simple, metal-free reaction conditions, simplicity of product isolation and good yields are key advantages of this methodology. 相似文献
15.
Girijesh Kumar Verma Gaurav ShuklaAnugula Nagaraju Abhijeet SrivastavaMaya Shankar Singh 《Tetrahedron》2014
An operationally simple and efficient one-pot straightforward method for the construction of 1,3-thiazolidin-4-ones has been developed by cyclocondensation of β-ketothioamides and an in situ generated acid anhydride from α-halocarboxylic acid in the presence of DCC at room temperature. The attractive features of this strategy include metal-free mild reaction conditions, short reaction time, and efficacy of forming consecutive C–S and C–N bonds and one ring in a single synthetic operation. Noteworthy, a Z-stereochemistry was observed for the exocyclic α-oxoketene moiety at 2-position of 1,3-thiazolidine ring. 相似文献
16.
A novel, one-pot, three-component synthesis of 4H-pyrido[1,2-a]pyrimidines is described. The reactive 1:1 zwitterionic intermediate, formed by the addition of isocyanides to dialkyl acetylenedicarboxylates, was trapped by N-(2-pyridyl)amides to produce the title compounds under mild reaction conditions in good yields. 相似文献
17.
18.
The unprecedented isoquinolinium zwitterionic salts with an unusual C-4 substitution pattern were efficiently prepared via the multicomponent reaction of in situ formed N-benzylisoquinolinium bromide with aromatic aldehydes and cyclic 1,3-dicarbonyl compounds. 相似文献
19.
Zhiguo Song Lianli Liu Yang Wang Xiaohu Sun 《Research on Chemical Intermediates》2012,38(3-5):1091-1099
A wide range of mono- and disubstituted 2,3-dihydroquinazolin-4(1H)-ones were synthesized via a one-pot three components condensation of isatoic anhydride, aldehydes, and ammonium salts or primary amines in the presence of aluminum methanesulfonate in EtOH/H2O solution. The catalyst is reusable and could be recycled for several runs without any distinct decrease in its efficiency. A plausible mechanism for this one-pot three components reaction was proposed. 相似文献
20.
Subhasis Samai 《Tetrahedron letters》2009,50(50):7096-402
A simple and efficient synthesis of 4-aryl-4,5-dihydro-1H-indeno[1,2-b]pyridine derivatives has been achieved via a four-component cyclocondensation of 1,3-indanedione, aromatic aldehydes, β-ketoesters and ammonium acetate in one-pot in the absence of catalyst and solvent at room temperature on grinding. The present approach offers several advantages such as shorter reaction times, higher yields, low cost, simple work-up and easy purification. 相似文献